Celia A. Schiffer

University of Massachusetts Chan Medical School

MedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 49 papers. Top paper: “Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit”.

Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit

The Journal of Infectious Diseases(2021)10.1093/infdis/jiab305

N/A

2.2DataRank · unranked

41 citations

James M. Anderson, Annaliesa S. Anderson, David Baker, Jay Bradner, Kyle R. Brimacombe +37 more

Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations

Immunity(2021)10.1016/j.immuni.2021.07.008

N/A

0.863DataRank · unranked

314 citations

Yiska Weisblum, Christopher O. Barnes, Fabian Schmidt, Dennis Schaefer-Babajew, Zijun Wang +23 more

Inhibiting HTLV-1 Protease: A Viable Antiviral Target

ACS Chemical Biology(2021)10.1021/acschembio.0c00975

N/A

0.483DataRank · unranked

24 citations

M. Henes, Nathaniel Talledge, L.N. Rusere, K. Kosovrasti, E.A. Nalivaika +6 more

Unique structural solution from a VH3-30 antibody targeting the hemagglutinin stem of influenza A viruses

Nature Communications(2021)10.1038/s41467-020-20879-6

N/A

0.449DataRank · unranked

19 citations

Derrick Deming, G.J. Lockbaum, Nattapol Attatippaholkun, Maliwan Kamkaew, Shurong Hou +7 more

Allosteric quinoxaline-based inhibitors of the flavivirus NS2B/NS3 protease

Bioorganic Chemistry(2022)10.1016/j.bioorg.2022.106269

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0.442DataRank · unranked

18 citations

Desaboini Nageswara Rao, Colby Johnson, Ala M. Shaqra, E.A. Nalivaika, Aria Jordan +4 more

Mucosal nanobody IgA as inhalable and affordable prophylactic and therapeutic treatment against SARS-CoV-2 and emerging variants

Frontiers in Immunology(2022)10.3389/fimmu.2022.995412

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0.442DataRank · unranked

18 citations

Fiachra Humphries, Roxie C. Girardin, Aaron Wallace, Monir Ejemel, Alla Amcheslavsky +17 more

Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state

Nature Communications(2022)10.1038/s41467-022-34752-1

N/A

0.425DataRank · unranked

16 citations

Adam K. Hedger, Wazo Myint, Vanivilasini Balachandran, Jonathan K. Watts, Celia A. Schiffer +2 more

HIV-1 protease inhibitors with a P1 phosphonate modification maintain potency against drug-resistant variants by increased interactions with flap residues

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115501

N/A

0.416DataRank · unranked

15 citations

L.N. Rusere, M. Henes, K. Kosovrasti, Desaboini Nageswara Rao, E. Spielvogel +7 more

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance

Journal of Molecular Biology(2022)10.1016/j.jmb.2022.167503

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0.416DataRank · unranked

15 citations

Desaboini Nageswara Rao, Sang V. Vo, M. Henes, K. Kosovrasti, Ashley N. Matthew +7 more

Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets

Nucleic Acids Research(2024)10.1093/nar/gkae1217

N/A

0.297DataRank · unranked

5 citations

Jing Zeng, Pengpeng Liu, My Anh Nguyen, Diego Suchenski Loustaunau, Daniel E. Bauer +4 more

Structural Analysis of Inhibitor Binding to Enterovirus-D68 3C Protease

Viruses(2025)10.3390/v17010075

N/A

0.273DataRank · unranked

4 citations

Ala M. Shaqra, Akbar Ali, Neşe Kurt Yılmaz, Celia A. Schiffer, Vincent Azzolino

Elucidating the Substrate Envelope of Enterovirus 68-3C Protease: Structural Basis of Specificity and Potential Resistance

Viruses(2024)10.3390/v16091419

N/A

0.259DataRank · unranked

4 citations

Ala M. Shaqra, Akbar Ali, Neşe Kurt Yılmaz, Celia A. Schiffer, Vincent Azzolino

Next generation APOBEC3 inhibitors: optimally designed for potency and nuclease stability

Nucleic Acids Research(2025)10.1093/nar/gkaf234

N/A

0.241DataRank · unranked

4 citations

Wazo Myint, Jeong Min Lee, Diego Suchenski Loustaunau, Vanivilasini Balachandran, Ala M. Shaqra +5 more

FcRn-enhancing mutations lead to increased and prolonged levels of the HIV CCR5-blocking monoclonal antibody leronlimab in the fetuses and newborns of pregnant rhesus macaques

mAbs(2024)10.1080/19420862.2024.2406788

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0.241DataRank · unranked

4 citations

Gabriela M. Webb, Helen L. Wu, Jason S. Reed, Jennifer Watanabe, Jodie L. Usachenko +6 more

HIV-1 VIF and human APOBEC3G interaction directly observed through molecular specific labeling using a new dual promotor vector

Journal of Magnetic Resonance(2022)10.1016/j.jmr.2022.107230

N/A

0.208DataRank · unranked

3 citations

Celia A. Schiffer, Hiroshi Matsuo, Wazo Myint

Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.08.15.504001

N/A

0.208DataRank · unranked

3 citations

Adam K. Hedger, Wazo Myint, Vanivilasini Balachandran, Jonathan K. Watts, Celia A. Schiffer +2 more

Covariation of amino acid positions in HIV-1 protease

UNC Libraries(2021)10.17615/md4d-fr74

N/A

0DataRank · unranked

1 citations

Noah G. Hoffman, Ronald Swanstrom, Celia A. Schiffer

Deciphering the Molecular Mechanism of HCV Protease Inhibitor Fluorination as a General Approach to Avoid Drug Resistance

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.30.470632

N/A

0DataRank · unranked

0 citations

Desaboini Nageswara Rao, Sang V. Vo, M. Henes, K. Kosovrasti, Ashley N. Matthew +7 more

A Sensitive Assay Using a Native Protein Substrate for Screening HIV-1 Maturation Inhibitors Targeting the Protease Cleavage Site between the Matrix and Capsid

UNC Libraries(2021)10.17615/tsh0-3j89

N/A

0DataRank · unranked

0 citations

William P. Janzen, Celia A. Schiffer, Sook Kyung Lee, Ronald Swanstrom, Nancy Cheng +2 more

Dual Inhibitors of Main Protease (MPro) and Cathepsin L as Potent Antivirals against SARS-CoV2

Journal of the American Chemical Society(2022)10.1021/jacs.2c04626

N/A

0DataRank · unranked

56 citations

Yongzhi Chen, G.J. Lockbaum, Sudeshna Sen, Sauradip Chaudhuri, Archie C. Reyes +9 more

Structure of the catalytically active APOBEC3G bound to a DNA oligonucleotide inhibitor reveals tetrahedral geometry of the transition state

Research Square(2022)10.21203/rs.3.rs-1964780/v1

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0DataRank · unranked

2 citations

Adam K. Hedger, Wazo Myint, Vanivilasini Balachandran, Jonathan K. Watts, Celia A. Schiffer +2 more

Bacterial pattern recognition in C. elegans by a nuclear hormone receptor

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.07.12.499718

N/A

0DataRank · unranked

0 citations

Samantha Y. Tse, Qiu Yu J. Huang, Celia A. Schiffer, Read Pukkila-Worley, Nicholas Peterson

Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans

Immunity(2023)10.1016/j.immuni.2023.01.027

N/A

0DataRank · unranked

41 citations

Samantha Y. Tse, Qiuyu Judy Huang, Khursheed A. Wani, Celia A. Schiffer, Read Pukkila-Worley +1 more

Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance

eLife(2023)10.7554/elife.80328

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0DataRank · unranked

23 citations

Sook-Kyung Lee, Shuntai Zhou, G.J. Lockbaum, M. Henes, Amy Sondgeroth +7 more

Selection of HIV-1 for resistance to fifth-generation protease inhibitors reveals two independent pathways to high-level resistance

UNC Libraries(2023)10.17615/k6f6-8629

N/A

0DataRank · unranked

0 citations

Amy Sondgeroth, Akbar Ali, E. Spielvogel, M. Henes, Sook-Kyung Lee +7 more

FruitFire: a luciferase based on a fruit fly metabolic enzyme

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.30.547126

N/A

0DataRank · unranked

0 citations

Jacqueto Zephyr, Markus‐Frederik Bohn, Celia A. Schiffer, Stephen C. Miller, Spencer T. Adams

Increasing intracellular dNTP levels improves prime editing efficiency

Nature Biotechnology(2024)10.1038/s41587-024-02405-x

N/A

0DataRank · unranked

29 citations

Karthikeyan Ponnienselvan, Thomas Nyalile, Sarah Oikemus, Anya T. Joynt, Sukanya Iyer +18 more

Next generation APOBEC3 inhibitors: Optimally designed for potency and nuclease stability

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.05.611238

N/A

0DataRank · unranked

3 citations

Wazo Myint, Jeong Min Lee, Diego Suchenski-Loustaunau, Vanivilasini Balachandran, Ala M. Shaqra +5 more

Direct delivery of stabilized Cas-embedded base editors achieves efficient and accurate editing of clinically relevant targets

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.08.579528

N/A

0DataRank · unranked

1 citations

Jing Zeng, Pengpeng Liu, My Anh Nguyen, Diego Suchenski Loustaunau, Daniel E. Bauer +4 more

Efficient convergent synthesis of 1,3-diazepinone nucleosides by ring-closing metathesis and direct glycosylation

RSC Advances(2024)10.1039/d4ra07318e

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0DataRank · unranked

0 citations

Jonathan Findell, Dinesh S. Barak, Celia A. Schiffer, Jonathan K. Watts, Akbar Ali +1 more

HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation

Nature Communications(2025)10.1038/s41467-025-60984-y

N/A

0DataRank · unranked

2 citations

Kazuhiro Matsuoka, Bakar A. Hassan, Rodolfo Ghirlando, Vanivilasini Balachandran, Ting-Hua Chen +6 more

Fluorinated HIV-1 protease inhibitors containing chiral hydroxyethylbenzene and indanol as P2′ ligands with potent activity against drug-resistant variants

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.118510

N/A

0DataRank · unranked

1 citations

E. Spielvogel, Desaboini Nageswara Rao, L.N. Rusere, Ala M. Shaqra, G.J. Lockbaum +6 more

A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction

Nature Communications(2020)10.1038/s41467-020-18058-8

N/A

0DataRank · unranked

185 citations

Qi Li, Shurong Hou, Zachary A. Schiller, Julia A. Tree, Aaron Wallace +20 more

Structural Analysis of Inhibitor Binding to the Feline Enteric Coronavirus (FECV) Main Protease

Viruses(2025)10.3390/v17111506

N/A

0DataRank · unranked

0 citations

Stephanie Moquin, Dustin Dovala, Jagroop Kaur, Neşe Kurt Yılmaz, Ala M. Shaqra +2 more

Crystal Structure of a Soluble APOBEC3G Variant Suggests ssDNA to Bind in a Channel that Extends between the Two Domains

Journal of Molecular Biology(2020)10.1016/j.jmb.2020.10.020

N/A

0DataRank · unranked

18 citations

Wazo Myint, Krista A. Delviks‐Frankenberry, Shurong Hou, Tapan Kanai, Vanivilasini Balachandran +7 more

Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere

Journal of Medicinal Chemistry(2020)10.1021/acs.jmedchem.0c00529

N/A

0DataRank · unranked

7 citations

G.J. Lockbaum, M. Henes, Sook-Kyung Lee, E. Spielvogel, Desaboini Nageswara Rao +7 more

Optimizing the refinement of merohedrally twinned P61 HIV-1 protease–inhibitor cocrystal structures

Acta Crystallographica Section D Structural Biology(2020)10.1107/s2059798320001989

N/A

0DataRank · unranked

1 citations

Florian Leidner, William E. Royer, Neşe Kurt Yılmaz, Celia A. Schiffer, G.J. Lockbaum

IgA MAb blocks SARS-CoV-2 Spike-ACE2 interaction providing mucosal immunity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.15.096719

N/A

0DataRank · unranked

27 citations

Qi Li, Shurong Hou, Zachary A. Schiller, Aaron Wallace, Alla Amcheslavsky +12 more

CryoEM Structure of CtBP2 Confirms Tetrameric Architecture

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.06.027573

N/A

0DataRank · unranked

0 citations

M. Michael Dcona, Xiaovan Deng, Dipankar Bandyopadhyay, Steven R. Grossman, Celia A. Schiffer +2 more

Deciphering complex mechanisms of resistance and loss of potency through coupled molecular dynamics and machine learning.

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.08.139105

N/A

0DataRank · unranked

0 citations

Neşe Kurt Yılmaz, Celia A. Schiffer, Florian Leidner

A Direct Interaction with RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In Vitro

UNC Libraries(2020)10.17615/0jjd-ap39

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0DataRank · unranked

0 citations

Ronald Swanstrom, Debra A. Ragland, Celia A. Schiffer, Sook-Kyung Lee

Development of a Novel Screening Strategy Designed to Discover a New Class of HIV Drugs

UNC Libraries(2020)10.17615/71vw-7m95

N/A

0DataRank · unranked

0 citations

Nancy Cheng, Mel Reichman, Celia A. Schiffer, William P. Janzen, Emily A. Hull-Ryde +3 more

Context Surrounding Processing Sites Is Crucial in Determining Cleavage Rate of a Subset of Processing Sites in HIV-1 Gag and Gag-Pro-Pol Polyprotein Precursors by Viral Protease

UNC Libraries(2020)10.17615/7mdb-fa43

N/A

0DataRank · unranked

0 citations

Ronald Swanstrom, Madhavi Kolli, Marc Potempa, Celia A. Schiffer, Sook Kyung Lee +1 more

Viral proteases: Structure, mechanism and inhibition

The Enzymes(2021)10.1016/bs.enz.2021.09.004

N/A

0DataRank · unranked

91 citations

Neşe Kurt Yılmaz, Celia A. Schiffer, Jacqueto Zephyr

Structural basis of substrate specificity in human cytidine deaminase family APOBEC3s

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100909

N/A

0DataRank · unranked

31 citations

Jeong Min Lee, Wazo Myint, Hiroshi Matsuo, Neşe Kurt Yılmaz, Celia A. Schiffer +1 more

Interactions of APOBEC3s with DNA and RNA

Current Opinion in Structural Biology(2021)10.1016/j.sbi.2020.12.004

N/A

0DataRank · unranked

21 citations

Shurong Hou, Celia A. Schiffer, Hiroshi Matsuo, Atanu Maiti

NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP)

Journal of Biological Chemistry(2021)10.1016/j.jbc.2021.100351

N/A

0DataRank · unranked

13 citations

Celia A. Schiffer, William E. Royer, Jeffry C. Nichols

Analyses of HIV proteases variants at the threshold of viability reveals relationships between processing efficiency and fitness

Virus Evolution(2021)10.1093/ve/veab103

N/A

0DataRank · unranked

7 citations

Julia M. Flynn, David Mavor, Celia A. Schiffer, Daniel N. Bolon, Gily Schneider-Nachum

Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.07.434227

N/A

0DataRank · unranked

48 citations

Yiska Weisblum, Christopher O. Barnes, Fabian Schmidt, Dennis Schaefer-Babajew, Julio C. C. Lorenzi +23 more