Christian M. Metallo

Also affiliated with University of California San Diego, La Jolla Bioengineering Institute

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 5%percentile

0.447Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

A Perturbation Cell Atlas of Human Induced Pluripotent Stem Cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.03.621734

Top 42%

0.447DataRank

Top 42%8 citations

Yesh Doctor, Amir Dailamy, Antoine Forget, Yi-Hung Lee, Becky Chinn +18 more

Papers

Driven by 63 papers — median percentile 29. Top paper: “Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis”.

Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis

Nature(2024)10.1038/s41586-024-08131-3

N/A

0.914DataRank · unranked

35 citations

Brenneth Stevens, Miguel Rendas, Harry Kane, Evan B. Lynch, Britta Kunkemoeller +14 more

Enhanced SREBP2-driven cholesterol biosynthesis by PKCλ/ι deficiency in intestinal epithelial cells promotes aggressive serrated tumorigenesis

Nature Communications(2023)10.1038/s41467-023-43690-5

N/A

0.881DataRank · unranked

30 citations

Juan F. Linares, Anxo Martínez-Ordóñez, Ángeles Durán, Tania Cid-Diaz, Hiroto Kinoshita +21 more

Fructose stimulated de novo lipogenesis is promoted by inflammation

Nature Metabolism(2020)10.1038/s42255-020-0261-2

N/A

0.866DataRank · unranked

320 citations

Giuseppe Di, Saskia Reibe, Darren C. Henstridge, Courtney R. Green, Alison Vrbanac +21 more

Insulin-regulated serine and lipid metabolism drive peripheral neuropathy

Nature(2023)10.1038/s41586-022-05637-6

N/A

0.778DataRank · unranked

178 citations

Jivani M. Gengatharan, Katie Frizzi, Grace H. McGregor, Cameron Martino, Gibraan Rahman +17 more

1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells

Journal of Lipid Research(2022)10.1016/j.jlr.2022.100281

N/A

0.752DataRank · unranked

27 citations

Ramya S. Kuna, Grace H. McGregor, Sanika Khare, Jivani M. Gengatharan, Thangaselvam Muthusamy +2 more

TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation

Cell Metabolism(2020)10.1016/j.cmet.2020.10.010

N/A

0.728DataRank · unranked

127 citations

Shannon M. Reilly, Mohammad Abu-Odeh, Anne N. Murphy, Sushil K. Mahata, Jinyu Zhang +7 more

Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy

European Heart Journal(2022)10.1093/eurheartj/ehac305

N/A

0.641DataRank · unranked

71 citations

Timon Seeger, Arne A.N. Bruyneel, Vittavat Termglinchan, Emma Monte, Esther W. Lim +17 more

The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62

Cell Reports(2022)10.1016/j.celrep.2022.110792

N/A

0.639DataRank · unranked

70 citations

Tania Cid-Diaz, Ángeles Durán, Marta Osrodek, Anxo Martínez-Ordóñez, Miguel Reina‐Campos +9 more

RalA controls glucose homeostasis by regulating glucose uptake in brown fat

Proceedings of the National Academy of Sciences(2018)10.1073/pnas.1801050115

N/A

0.601DataRank · unranked

54 citations

Morgan Dragan, Claudia Cordon, Shannon M. Reilly, Chao-Wei Hung, Wenmin Xia +11 more

Impaired branched-chain amino acid (BCAA) catabolism during adipocyte differentiation decreases glycolytic flux

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.108004

N/A

0.460DataRank · unranked

9 citations

Lynn M. Alaeddine, Karl A. Wessendorf-Rodriguez, Rory Turner, Merve Elmastas, Justin D. Hover +6 more

A Perturbation Cell Atlas of Human Induced Pluripotent Stem Cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.03.621734

Top 42%

0.447DataRank

Top 42%8 citations

Yesh Doctor, Amir Dailamy, Antoine Forget, Yi-Hung Lee, Becky Chinn +18 more

Divergent amino acid and sphingolipid metabolism in patients with inherited neuro-retinal disease

Molecular Metabolism(2023)10.1016/j.molmet.2023.101716

N/A

0.442DataRank · unranked

18 citations

Roberto Bonelli, Brendan R. E. Ansell, Simone Tzaridis, Michal K. Handzlik, Grace H. McGregor +12 more

iPSC–derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function

Journal of Clinical Investigation(2023)10.1172/jci163771

N/A

0.385DataRank · unranked

12 citations

Brendan R. E. Ansell, Sarah Giles, Regis Fallon, Sarah Harkins‐Perry, Takayuki Nagasaki +15 more

Daily running enhances molecular and physiological circadian rhythms in skeletal muscle

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.10.19.346015

N/A

0.269DataRank · unranked

5 citations

Drew Duglan, Megan Vaughan, Michal K. Handzlik, Weiwei Fan, Ruth T. Yu +11 more

Inter-organelle crosstalk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.09.24.509326

N/A

0.241DataRank · unranked

4 citations

Avi Kumar, Hector M. Galvez, Karl A. Wessendorf-Rodriguez, Courtney R. Green, Grace H. McGregor +5 more

Lipid availability influences the metabolic maturation of human pluripotent stem cell-derived cardiomyocytes

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.03.14.991927

N/A

0.241DataRank · unranked

4 citations

Mehmet G. Badur, Sean Spiering, Ajit S. Divakaruni, Noah Meurs, Michael S. Yu +5 more

NaCT ( SLC13A5 ) facilitates citrate import and metabolism under nutrient-limited conditions

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.08.439058

N/A

0.208DataRank · unranked

3 citations

Thekla Cordes, Anna Thalacker‐Mercer, Ana M. Pajor, Anne N. Murphy, Christian M. Metallo +1 more

Impaired BCAA catabolism during adipocyte differentiation decreases glycolytic flux

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.05.27.493780

N/A

0.165DataRank · unranked

2 citations

Karl A. Wessendorf-Rodriguez, Rory Turner, Justin D. Hover, Anne N. Murphy, Christian M. Metallo +2 more

Quantifying acyl-chain diversity in isobaric compound lipids containing monomethyl branched-chain fatty acids

Journal of Lipid Research(2024)10.1016/j.jlr.2024.100677

N/A

0.165DataRank · unranked

2 citations

Matthew J. Kolar, Grace H. McGregor, Andrew T. Nelson, Martina Wallace, Christian M. Metallo +1 more

Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.09.434648

N/A

0DataRank · unranked

0 citations

Daniella McDonald, Amir Dailamy, Yan Wu, Thekla Cordes, Kun Zhang +4 more

Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.08.451710

N/A

0DataRank · unranked

0 citations

Ariane Pessentheiner, Sean C. Purcell, Courtney R. Green, Natalie DeForest, Karl Willert +5 more

Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages

Nature Metabolism(2022)10.1038/s42255-022-00565-1

N/A

0DataRank · unranked

115 citations

Antonia Henne, Mario Lauterbach, Eike Geißmar, Fabian Nikolka, Celia Kho +20 more

Acetate reprograms gut microbiota during alcohol consumption

Nature Communications(2022)10.1038/s41467-022-31973-2

N/A

0DataRank · unranked

100 citations

Lívia S. Zaramela, Bei Gao, Mallory Embree, Janna Tarasova, Seth J. Parker +14 more

Microbiota control of maternal behavior regulates early postnatal growth of offspring

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.02.130682

N/A

0DataRank · unranked

2 citations

Martina Wallace, Jivani M. Gengatharan, Annalee Fürst, Lars Bode, Christian M. Metallo +2 more

Non-targeted metabolomics identifies erythronate accumulation in cancer cells

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.12.04.519010

N/A

0DataRank · unranked

2 citations

Mark A. Keibler, Wentao Dong, Jenny Ghelfi, Thekla Cordes, Tamara Kanashova +8 more

Hepatic serine and lipid metabolism drive diabetic peripheral neuropathy

Research Square(2022)10.21203/rs.3.rs-1189916/v1

N/A

0DataRank · unranked

0 citations

Michal K. Handzlik, Jivani M. Gengatharan, Katie Frizzi, Grace H. McGregor, Cameron Martino +14 more

Collagen remodeling dictates pancreatic cancer bioenergetics and outcome through DDR1 activation or degradation

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.04.02.486837

N/A

0DataRank · unranked

0 citations

Fei Yang, Rao Fu, Brittney Trinh, Nina Sun, Junlai Liu +16 more

Divergent amino acid and sphingolipid metabolism in patients with inherited neuro-retinal disease

medRxiv(2022)10.1101/2022.11.09.22281993

N/A

0DataRank · unranked

0 citations

Roberto Bonelli, Brendan R. E. Ansell, Simone Tzaridis, Michal K. Handzlik, Grace H. McGregor +12 more

Cryptochromes Suppress HIF1α in Muscles

iScience(2020)10.1016/j.isci.2020.101338

N/A

0DataRank · unranked

37 citations

Martina Wallace, Michal K. Handzlik, Alanna B. Chan, Christian M. Metallo, Katja Lamia +1 more

Sources and Sinks of Serine in Nutrition, Health, and Disease

Annual Review of Nutrition(2023)10.1146/annurev-nutr-061021-022648

N/A

0DataRank · unranked

59 citations

Christian M. Metallo, Michal K. Handzlik

Inter-organelle cross-talk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

Science Advances(2023)10.1126/sciadv.adf0138

N/A

0DataRank · unranked

57 citations

Avi Kumar, Karl A. Wessendorf-Rodriguez, Hector M. Galvez, Courtney R. Green, Grace H. McGregor +5 more

Statins Limit Coenzyme Q Synthesis and Metabolically Synergize with MEK Inhibition in Pancreatic Tumors

Cancer Research(2020)10.1158/0008-5472.can-19-3415

N/A

0DataRank · unranked

19 citations

Christian M. Metallo, Thekla Cordes

Nutrient regulation of the islet epigenome controls adaptive insulin secretion

Journal of Clinical Investigation(2023)10.1172/jci165208

N/A

0DataRank · unranked

25 citations

Fenfen Liu, Austin R. Harrington, Johanna Y. Fleischman, Martina Wallace, Francesca Mulas +17 more

PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression

Cancer Cell(2020)10.1016/j.ccell.2020.05.018

N/A

0DataRank · unranked

154 citations

Masayuki Sugimoto, Esperanza Arias, Hiroaki Kasashima, Thekla Cordes, Juan F. Linares +14 more

Stable Isotope-Assisted Untargeted Metabolomics Identifies ALDH1A1-Driven Erythronate Accumulation in Lung Cancer Cells

Biomedicines(2023)10.3390/biomedicines11102842

N/A

0DataRank · unranked

6 citations

Mark A. Keibler, Wentao Dong, Jenny Ghelfi, Thekla Cordes, Tamara Kanashova +8 more

Glycocalyx engineering with heparan sulfate mimetics attenuates Wnt activity during adipogenesis to promote glucose uptake and metabolism

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.104611

N/A

0DataRank · unranked

7 citations

Ariane Pessentheiner, Sean C. Purcell, Courtney R. Green, Natalie DeForest, Karl Willert +5 more

Supplementary Data from Establishment of Patient-Derived Succinate Dehydrogenase–Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response

INDIGO (University of Illinois at Chicago)(2023)10.1158/1078-0432.22482656.v1

Top 100%

0DataRank

Top 100%0 citations

Shruti Bhargava, Avi Kumar, Adam M. Burgoyne, Chih‐Min Tang, Hyunho Yoon +17 more

Data from Establishment of Patient-Derived Succinate Dehydrogenase–Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response

(2023)10.1158/1078-0432.c.6530975.v1

N/A

0DataRank · unranked

0 citations

Shruti Bhargava, Avi Kumar, Adam M. Burgoyne, Chih‐Min Tang, Hyunho Yoon +17 more

EGFR + lung adenocarcinomas coopt alveolar macrophage metabolism and function to support EGFR signaling and growth

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.04.15.536974

N/A

0DataRank · unranked

0 citations

Thekla Cordes, Ziyan Xu, Kacie A. Traina, Camila Robles-Oteíza, Deborah Ayeni +10 more

Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis

Cell Metabolism(2024)10.1016/j.cmet.2024.10.016

N/A

0DataRank · unranked

40 citations

Michal K. Handzlik, Zoya Y Chih, Maureen L. Ruchhoeft, Patrick Secrest, Ethan L. Ashley +5 more

Bempedoic acid suppresses diet-induced hepatic steatosis independently of ATP-citrate lyase

Cell Metabolism(2024)10.1016/j.cmet.2024.10.014

N/A

0DataRank · unranked

35 citations

Ramya S. Kuna, Laura V. Pinheiro, Phuong Nguyen, Jaclyn E. Welles, Jack M. Drummond +17 more

Extracellular serine and glycine are required for mouse and human skeletal muscle stem and progenitor cell function

Molecular Metabolism(2020)10.1016/j.molmet.2020.101106

N/A

0DataRank · unranked

71 citations

Jamie Blum, Esther W. Lim, Michal K. Handzlik, Ern Hwei Hannah Fong, Anthony C. Ko +10 more

EGFR-Driven Lung Adenocarcinomas Co-opt Alveolar Macrophage Metabolism and Function to Support EGFR Signaling and Growth

Cancer Discovery(2024)10.1158/2159-8290.cd-23-0434

N/A

0DataRank · unranked

34 citations

Thekla Cordes, Ziyan Xu, Ramya S. Kuna, Kacie A. Traina, Camila Robles-Oteíza +13 more

Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress

Nature Metabolism(2024)10.1038/s42255-024-01143-3

N/A

0DataRank · unranked

30 citations

Camila Martínez Calejman, John D. Haley, Miranda E. Kelly, Huawei Li, Maria Gaughan +22 more

Serine and glycine physiology reversibly modulate retinal and peripheral nerve function

Cell Metabolism(2024)10.1016/j.cmet.2024.07.021

N/A

0DataRank · unranked

19 citations

Regis Fallon, Caleb Bates, Yoichiro Ideguchi, Takayuki Nagasaki, Michal K. Handzlik +14 more

Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria

Science Advances(2024)10.1126/sciadv.adl0389

N/A

0DataRank · unranked

18 citations

Alice Ma, Timothy M. Moore, Dane M. Wolf, Nicole L. Yang, Peter Tran +18 more

Protocol to generate human liver spheroids to study liver fibrosis induced by metabolic stress

STAR Protocols(2024)10.1016/j.xpro.2024.103111

N/A

0DataRank · unranked

18 citations

Wonseok Lee, Xiao Liu, Haeum Jang, Sadatsugu Sakane, Raquel Carvalho‐Gontijo Weber +6 more

Tracing insights into de novo lipogenesis in liver and adipose tissues

Seminars in Cell and Developmental Biology(2020)10.1016/j.semcdb.2020.02.012

N/A

0DataRank · unranked

95 citations

Christian M. Metallo, Martina Wallace

Serine restriction alters sphingolipid diversity to constrain tumour growth

Nature(2020)10.1038/s41586-020-2609-x

N/A

0DataRank · unranked

315 citations

Thekla Cordes, Michal K. Handzlik, Le You, Esther W. Lim, Jivani M. Gengatharan +7 more

Metabolic Deficiencies Underlie Plasmacytoid Dendritic Cell Exhaustion After Viral Infection

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.28.582551

N/A

0DataRank · unranked

3 citations

Yeara Jo, Mónica Macal, Ziyan Fang, Fawziyah S. Khatri, Alicia L Codrington +11 more

Metabolic deficiencies underlie reduced plasmacytoid dendritic cell IFN-I production following viral infection

Nature Communications(2025)10.1038/s41467-025-56603-5

N/A

0DataRank · unranked

17 citations

Yeara Jo, Carolina Chiale, Mónica Macal, Ziyan Fang, Fawziyah S. Khatri +11 more

In vivo itaconate tracing reveals degradation pathway and turnover kinetics

Nature Metabolism(2025)10.1038/s42255-025-01363-1

N/A

0DataRank · unranked

11 citations

Alexander T. Williams, Alfredo Lucas, Mack B. Reynolds, Emeline Joulia, Maureen L. Ruchhoeft +5 more

Enhancing cardiac serine biosynthesis mitigates the progression of dilated cardiomyopathy in mice

Metabolism(2025)10.1016/j.metabol.2025.156395

N/A

0DataRank · unranked

3 citations

Anne‐Maj Samuelsson, Nikë Bharucha, Xueyi Li, Rohin Ramchandani, Rachel Baum +8 more

1-Deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.13.652513

N/A

0DataRank · unranked

2 citations

Nicolas-Frédéric Lipp, Olivia Seidel, Riya Varma, Aurélie Laguerre, Kristina Solorio-Kirpichyan +10 more

Targeting serine dehydratase supports amino acid homeostasis and skin repair

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.23.683531

N/A

0DataRank · unranked

1 citations

Ethan L. Ashley, Patrick Tseng, Citlalic Arechiga, Yuqiong Liang, Aurélie Laguerre +12 more

A Small Molecule Fluorogenic Probe for the Detection of Sphingosine in Living Cells

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.06.27.175661

N/A

0DataRank · unranked

0 citations

Neel Mittal, Esther W. Lim, Christian M. Metallo, Neal K. Devaraj, Andrew K. Rudd

Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes

Cell Reports(2020)10.1016/j.celrep.2020.107925

N/A

0DataRank · unranked

409 citations

Wesley L. McKeithan, Arne A.N. Bruyneel, Sean Spiering, Larissa Hörmann, Bärbel Ulmer +24 more

Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

Cancer Cell(2021)10.1016/j.ccell.2021.02.016

N/A

0DataRank · unranked

221 citations

Fei Yang, Rao Fu, Xin Li, Randall P. French, Evangeline Mose +15 more

Itaconate Alters Succinate and Coenzyme A Metabolism via Inhibition of Mitochondrial Complex II and Methylmalonyl-CoA Mutase

Metabolites(2021)10.3390/metabo11020117

N/A

0DataRank · unranked

78 citations

Christian M. Metallo, Thekla Cordes

NaCT/SLC13A5 facilitates citrate import and metabolism under nutrient-limited conditions

Cell Reports(2021)10.1016/j.celrep.2021.109701

N/A

0DataRank · unranked

62 citations

Thekla Cordes, Anna Thalacker‐Mercer, Ana M. Pajor, Anne N. Murphy, Christian M. Metallo +1 more

Microbiota control of maternal behavior regulates early postnatal growth of offspring

Science Advances(2021)10.1126/sciadv.abe6563

N/A

0DataRank · unranked

33 citations

Andre Mu, Martina Wallace, Jivani M. Gengatharan, Annalee Fürst, Lars Bode +3 more

Progressive alterations in amino acid and lipid metabolism correlate with peripheral neuropathy in Polg D257A mice

Science Advances(2021)10.1126/sciadv.abj4077

N/A

0DataRank · unranked

23 citations

Michal K. Handzlik, Elijah Trefts, Jivani M. Gengatharan, Carlos M. Pondevida, Reuben J. Shaw +2 more

Charting oncogenicity of genes and variants across lineages via multiplexed screens in teratomas

iScience(2021)10.1016/j.isci.2021.103149

N/A

0DataRank · unranked

4 citations

Daniella McDonald, Amir Dailamy, Yan Wu, Thekla Cordes, Kun Zhang +4 more

Christian M. Metallo

Indexed papers

Top data-sharing exemplar

Papers