Arun K. Ghosh

ChemistryMedicineImmunology and MicrobiologyBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

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Papers

Driven by 48 papers. Top paper: “A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication”.

A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

Nature Communications(2021)10.1038/s41467-021-20900-6

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0.792DataRank · unranked

196 citations

Nobuyo Higashi‐Kuwata, Hironori Hayashi, Srinivasa Rao Allu, Jakka Raghavaiah, Haydar Bulut +18 more

Synthesis of amide derivatives for electron deficient amines and functionalized carboxylic acids using EDC and DMAP and a catalytic amount of HOBt as the coupling reagents

Tetrahedron Letters(2020)10.1016/j.tetlet.2020.152719

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0.646DataRank · unranked

73 citations

Dana Shahabi, Arun K. Ghosh

Chloropyridinyl Esters of Nonsteroidal Anti-Inflammatory Agents and Related Derivatives as Potent SARS-CoV-2 3CL Protease Inhibitors

Molecules(2021)10.3390/molecules26195782

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0.406DataRank · unranked

14 citations

Dana Shahabi, Monika Yadav, Satish Kovela, Brandon J. Anson, Emma K. Lendy +8 more

A structure-guided taxonomicbased approach to the design of broad-spectrum coronavirus protease inhibitors

Acta Crystallographica Section A Foundations and Advances(2021)10.1107/s010876732109485x

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0.104DataRank · unranked

1 citations

Sarah E. St. John, Emma K. Lendy, Brandon J. Anson, Mackenzie E. Chapman, Arun K. Ghosh +1 more

An enzymatic route to the synthesis of tricyclic fused hexahydrofuranofuran P2-Ligand for a series of highly potent HIV-1 protease inhibitors

Tetrahedron Letters(2024)10.1016/j.tetlet.2024.155013

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0.104DataRank · unranked

1 citations

Ashish Sharma, Somayeh Ghazi, Arun K. Ghosh

Highly Diastereoselective Intramolecular Asymmetric Oxidopyrylium-olefin [5 + 2] Cycloaddition and Synthesis of 8-Oxabicyclo[3.2.1]oct-3-enone Containing Ring Systems

The Journal of Organic Chemistry(2021)10.1021/acs.joc.1c00600

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0DataRank · unranked

17 citations

Monika Yadav, Arun K. Ghosh

Spliceostatins and Derivatives: Chemical Syntheses and Biological Properties of Potent Splicing Inhibitors

Journal of Natural Products(2021)10.1021/acs.jnatprod.1c00100

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0DataRank · unranked

17 citations

Jennifer L. Mishevich, Melissa S. Jurica, Arun K. Ghosh

Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PRS17

Biochemical and Biophysical Research Communications(2021)10.1016/j.bbrc.2021.05.094

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0DataRank · unranked

8 citations

Daniel W. Kneller, Arun K. Ghosh, Irene T. Weber, Johnson Agniswamy

Herboxidiene Features That Mediate Conformation-Dependent SF3B1 Interactions to Inhibit Splicing

ACS Chemical Biology(2021)10.1021/acschembio.0c00965

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0DataRank · unranked

12 citations

Srinivasa Rao Allu, Patricia Mendez, Guddeti Chandrashekar Reddy, Hannah M. Maul-Newby, Arun K. Ghosh +2 more

U2 snRNA structure is influenced by SF3A and SF3B proteins but not by SF3B inhibitors

PLoS ONE(2021)10.1371/journal.pone.0258551

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0DataRank · unranked

4 citations

Meredith Stevers, Arun K. Ghosh, Melissa S. Jurica, Veronica K. Urabe

Design and synthesis of herboxidiene derivatives that potently inhibit in vitro splicing

Organic & Biomolecular Chemistry(2021)10.1039/d0ob02532a

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0DataRank · unranked

5 citations

Srinivasa Rao Allu, Guddeti Chandrashekar Reddy, Adriana López, Patricia Mendez, Melissa S. Jurica +1 more

Beyond darunavir: recent development of next generation HIV-1 protease inhibitors to combat drug resistance

Chemical Communications(2022)10.1039/d2cc04541a

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0DataRank · unranked

24 citations

Irene T. Weber, Hiroaki Mitsuya, Arun K. Ghosh

Fluorine Modifications Contribute to Potent Antiviral Activity against Highly Drug-Resistant HIV-1 and Favorable Blood-Brain Barrier Penetration Property of Novel Central Nervous System-Targeting HIV-1 Protease Inhibitors In Vitro

Antimicrobial Agents and Chemotherapy(2022)10.1128/aac.01715-21

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0DataRank · unranked

9 citations

Ravikiran S. Yedidi, Pedro Miguel Salcedo-Gómez, Hironori Hayashi, Kazuya Hasegawa, Cuthbert D. Martyr +3 more

Design, Synthesis and X‐Ray Structural Studies of Potent HIV‐1 Protease Inhibitors Containing C‐4 Substituted Tricyclic Hexahydro‐Furofuran Derivatives as P2 Ligands

ChemMedChem(2022)10.1002/cmdc.202200058

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0DataRank · unranked

6 citations

Satish Kovela, Ashish Sharma, Dana Shahabi, Ajay K. Ghosh, Denver R. Hopkins +11 more

Total Syntheses of the Proposed Structure of Iriomoteolide-1a, -1b and Synthesis of Three Derivatives for Structural Studies

Marine Drugs(2022)10.3390/md20100587

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0DataRank · unranked

6 citations

Hao Yuan, Arun K. Ghosh

HIV-1 protease with 10 lopinavir and darunavir resistance mutations exhibits altered inhibition, structural rearrangements and extreme dynamics

Journal of Molecular Graphics and Modelling(2022)10.1016/j.jmgm.2022.108315

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0DataRank · unranked

6 citations

Yuan-Fang Wang, Daniel W. Kneller, Andrey Kovalevsky, Arun K. Ghosh, Robert W. Harrison +2 more

Convergent synthesis of (+)-carambolaflavone A, an antidiabetic agent using a bismuth triflate-catalyzed C -aryl glycosylation

Organic & Biomolecular Chemistry(2022)10.1039/d2ob00038e

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0DataRank · unranked

4 citations

William L. Robinson, John Gulliver, Hannah M. Simpson, Arun K. Ghosh

Highly diastereoselective asymmetric syn-aldol reactions of (R)-(N-tosyl)phenylalaninol propionate-derived titanium enolate and bidentate aromatic and aliphatic aldehydes

Tetrahedron Letters(2022)10.1016/j.tetlet.2022.153954

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0DataRank · unranked

1 citations

John P. Gulliver, Arun K. Ghosh

A convenient synthesis of (3S,3aR,5R,7aS,8S)-Hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-ol, a high-affinity nonpeptidyl ligand for highly potent HIV-1 protease inhibitors

Tetrahedron Letters(2022)10.1016/j.tetlet.2022.154161

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0DataRank · unranked

1 citations

Shivaji B. Markad, Arun K. Ghosh

SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads

Bioorganic & Medicinal Chemistry Letters(2023)10.1016/j.bmcl.2023.129489

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0DataRank · unranked

12 citations

Dana Shahabi, Mackenzie E.C. Imhoff, Satish Kovela, Ashish Sharma, Shin-ichiro Hattori +4 more

Development of a new class of potent and highly selective G protein-coupled receptor kinase 5 inhibitors and structural insight from crystal structures of inhibitor complexes

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115931

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0DataRank · unranked

12 citations

Amol D. Sonawane, Manda Rajesh, Ranjith Kumar Gadi, J.J.G. Tesmer, Arun K. Ghosh +1 more

Synthesis of optically active SARS-CoV-2 Mpro inhibitor drug nirmatrelvir (Paxlovid): an approved treatment of COVID-19

Organic & Biomolecular Chemistry(2023)10.1039/d3ob00653k

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0DataRank · unranked

8 citations

Monika Yadav, Arun K. Ghosh

Evaluation of darunavir-derived HIV-1 protease inhibitors incorporating P2′ amide-derivatives: Synthesis, biological evaluation and structural studies

Bioorganic & Medicinal Chemistry Letters(2023)10.1016/j.bmcl.2023.129168

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0DataRank · unranked

8 citations

Dana Shahabi, Maya Kipfmiller, Ajay K. Ghosh, Megan Johnson, Yuan-Fang Wang +5 more

Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological evaluation

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115385

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0DataRank · unranked

5 citations

Jennifer L. Mishevich, Satish Kovela, Ryan Shaktah, Ajay K. Ghosh, Megan Johnson +9 more

Total Synthesis of Neuroprotective Agents, (+)-Lycibarbarine A and (−)-Lycibarbarine B

The Journal of Organic Chemistry(2023)10.1021/acs.joc.3c00749

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0DataRank · unranked

4 citations

M.J. Harper, William L. Robinson, Arun K. Ghosh

Four decades of continuing innovations in the development of antiretroviral therapy for HIV/AIDS: Progress to date and future challenges

Global Health & Medicine(2023)10.35772/ghm.2023.01013

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0DataRank · unranked

40 citations

Arun K. Ghosh

Control of Biofilm Formation by an Agrobacterium tumefaciens Pterin-Binding Periplasmic Protein Conserved Among Pathogenic Bacteria

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.18.567607

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0DataRank · unranked

0 citations

Justin L. Eagan, Nathan Feirer, Kaleb Boswinkle, G. Minasov, L. Shuvalova +7 more

BACE1 inhibitor drugs for the treatment of Alzheimer's disease: Lessons learned, challenges to overcome, and future prospects†

Global Health & Medicine(2024)10.35772/ghm.2024.01033

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0DataRank · unranked

22 citations

Arun K. Ghosh

Exploration of P1 and P4 modifications of nirmatrelvir: Design, synthesis, biological evaluation, and X-ray structural studies of SARS-CoV-2 Mpro inhibitors

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116132

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0DataRank · unranked

15 citations

Monika Yadav, Iddum Satyanarayana, Somayeh Ghazi, Emma K. Lendy, Uttara Jayashankar +8 more

Control of biofilm formation by an Agrobacterium tumefaciens pterin-binding periplasmic protein conserved among diverse Proteobacteria

Proceedings of the National Academy of Sciences(2024)10.1073/pnas.2319903121

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0DataRank · unranked

7 citations

Justin L. Eagan, Nathan Feirer, Kaleb Boswinkle, G. Minasov, L. Shuvalova +7 more

SF3B1 thermostability as an assay for splicing inhibitor interactions

Journal of Biological Chemistry(2024)10.1016/j.jbc.2024.108135

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0DataRank · unranked

5 citations

Guddeti Chandrashekar Reddy, Bruno Melillo, Benjamin F. Cravatt, Arun K. Ghosh, Melissa S. Jurica +1 more

Design, synthesis, and X-ray structural studies of a series of highly potent, selective, and drug-like G protein-coupled receptor kinase 5 inhibitors

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.117024

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0DataRank · unranked

6 citations

Yueyi Chen, Ranjith Kumar Gadi, Amol Sonawane, Sandali Piladuwa Gamage, J.J.G. Tesmer +1 more

Design of substituted tetrahydrofuran derivatives for HIV-1 protease inhibitors: synthesis, biological evaluation, and X-ray structural studies

Organic & Biomolecular Chemistry(2024)10.1039/d4ob00506f

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0DataRank · unranked

2 citations

Daniel Lee, Ashish Sharma, Megan Johnson, Ajay K. Ghosh, Yuan-Fang Wang +6 more

Syntheses of optically active monapterin, 7,8-dihydromonapterin, and 5,6,7,8-tetrahydromonapterin from l -xylose

RSC Advances(2024)10.1039/d4ra07179d

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0DataRank · unranked

1 citations

Ashish Sharma, Satish Nagam, Clay Fuqua, Arun K. Ghosh

Potent, Selective, and Drug‐Like G Protein‐Coupled Receptor Kinase 5 and 6 Inhibitors: Design, Synthesis, and X‐Ray Structural Studies

ChemMedChem(2025)10.1002/cmdc.202500257

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0DataRank · unranked

4 citations

Ranjith Kumar Gadi, Yueyi Chen, Sandali Piladuwa Gamage, Kathryn P. McCauley, J.J.G. Tesmer +1 more

Potent and selective G protein-coupled receptor kinase 5 inhibitors: Design, synthesis, evaluation, and X-ray structural studies

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.118393

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0DataRank · unranked

1 citations

Manda Rajesh, Ranjith Kumar Gadi, Yueyi Chen, Natalie M. Galvan, J.J.G. Tesmer +1 more

Potent HIV‑1 protease inhibitors containing oxabicyclo octanol-derived P2-ligands: Design, synthesis, and X‑ray structural studies of inhibitor-HIV-1 protease complexes

Bioorganic & Medicinal Chemistry Letters(2025)10.1016/j.bmcl.2025.130109

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0DataRank · unranked

3 citations

Monika Yadav, Ashish Sharma, Megan Johnson, Ajay K. Ghosh, Rangu Prasad +5 more

TiCl4-Mediated Diastereoselective Tandem Reactions of Functionalized Keto Esters and Dihydrofurans: Synthesis of Substituted Tricyclic Hexahydro-2H-benzocycloheptafurans

The Journal of Organic Chemistry(2025)10.1021/acs.joc.5c00381

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0DataRank · unranked

2 citations

Tristan John McDonald, Nilanjana Chakraborty, Arun K. Ghosh

TiCl4-Promoted Intramolecular Friedel–Crafts Cyclization of α-Keto-phenylbutanoates: Synthesis of Substituted Indane and Indene Derivatives

Synlett(2025)10.1055/a-2698-1214

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0DataRank · unranked

1 citations

Tristan John McDonald, Arun K. Ghosh

Design, synthesis, evaluation and X-ray structural studies of potent HIV-1 protease inhibitors containing substituted oxaspirocyclic carbamates as the P2 ligands

European Journal of Medicinal Chemistry(2025)10.1016/j.ejmech.2025.117880

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0DataRank · unranked

0 citations

Ryan Shaktah, Ajay K. Ghosh, Megan Johnson, Dipendra Bhandari, Masayuki Amano +4 more

Diastereoselective intramolecular oxidopyrylium–alkene [5 + 2]-cycloaddition of substrates with a β-chiral center on alkene tethers: synthesis of 8-oxabicyclo-[3.2.1]-octenone heterocycles

Organic & Biomolecular Chemistry(2025)10.1039/d5ob01429h

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0DataRank · unranked

0 citations

Denver R. Hopkins, Arun K. Ghosh

High-Throughput Cardiac Hypertrophy Phenotyping Supports Lead Optimization of GRK5 Inhibitors

ACS Medicinal Chemistry Letters(2025)10.1021/acsmedchemlett.5c00528

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0DataRank · unranked

0 citations

Anca Remes, Carmen Carrillo García, Amol Sonawane, Ranjith Kumar Gadi, Arun K. Ghosh +4 more

Drug Development and Medicinal Chemistry Efforts toward SARS‐Coronavirus and Covid‐19 Therapeutics

ChemMedChem(2020)10.1002/cmdc.202000223

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0DataRank · unranked

316 citations

Margherita Brindisi, Dana Shahabi, Mackenzie E. Chapman, Andrew D. Mesecar, Arun K. Ghosh

Catalytic function and substrate specificity of alpha and beta coronavirus papain-like proteases: targeting human NL63, SARS-CoV and SARS-CoV-2 (Covid-19) with designed inhibitors

Biophysical Journal(2022)10.1016/j.bpj.2021.11.1792

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0DataRank · unranked

0 citations

Courtney M. Daczkowski, Arun K. Ghosh, Andrew D. Mesecar, Mackenzie E. Chapman

Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity

Scientific Reports(2020)10.1038/s41598-020-65993-z

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0DataRank · unranked

82 citations

Shin‐ichiro Hattori, Hiromi Aoki-Ogata, Hironori Hayashi, Debananda Das, Manabu Aoki +6 more

GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

mBio(2020)10.1128/mbio.01833-20

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0DataRank · unranked

79 citations

Nobuyo Higshi-Kuwata, Jakka Raghavaiah, Debananda Das, Haydar Bulut, David A. Davis +11 more

The Chiron Approach to (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol, a Key Subunit of HIV-1 Protease Inhibitor Drug, Darunavir

The Journal of Organic Chemistry(2020)10.1021/acs.joc.0c02396

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0DataRank · unranked

14 citations

Shivaji B. Markad, William L. Robinson, Arun K. Ghosh

A Mouse Model for Betacoronavirus Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant

Carolina Digital Repository (University of North Carolina at Chapel Hill)(2020)10.17615/dwgs-ep23

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3 citations

Eric Donaldson, Arun K. Ghosh, Robin Gopal, Trevor Scobey, Maria Zambon +14 more