Tomas Yeo

Also affiliated with Columbia University Irving Medical Center, CNR de la Résistance aux Antibiotiques, Columbia University

MedicineComputer ScienceBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 27 papers. Top paper: “A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin”.

A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin

Nature Communications(2022)10.1038/s41467-022-33403-9

N/A

0.624DataRank · unranked

63 citations

Jinxin V. Pei, James E. O. Rosling, Vandana Thathy, Dongdi Li, Yi Xue +26 more

Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

Nature Communications(2023)10.1038/s41467-023-36921-2

N/A

0.524DataRank · unranked

32 citations

Charisse Flerida A. Pasaje, Robert L. Summers, Pamela Magistrado-Coxen, Kyra A. Schindler, Victoriano Corpas‐López +25 more

Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages

PLoS Pathogens(2022)10.1371/journal.ppat.1010926

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0.515DataRank · unranked

30 citations

Sachel Mok, Tarrick Qahash, Tomas Yeo, Jade Bath, Lindsey Orchard +6 more

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Science Advances(2023)10.1126/sciadv.adi2364

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0.510DataRank · unranked

29 citations

Tomas Yeo, Davin Hong, Melanie J. Shears, Leila S. Ross, Kurt E. Ward +19 more

Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites

Scientific Reports(2021)10.1038/s41598-021-81486-z

N/A

0.489DataRank · unranked

25 citations

Richard T. Eastman, Kathryn J. Wicht, Daniel J. Jansen, Daniel C. Talley, Benjamin A. Sigmon +25 more

Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum

ACS Infectious Diseases(2023)10.1021/acsinfecdis.3c00310

N/A

0.477DataRank · unranked

13 citations

Kurt E. Ward, Ryan K. Muir, Stephanie Kabeche, Euna Yoo, Tomas Yeo +11 more

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission

Science Advances(2024)10.1126/sciadv.adq1383

N/A

0.241DataRank · unranked

4 citations

Antima Gupta, Laura Drought, Avnish Patel, John Okombo, Mariëtte van der Watt +42 more

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.02.543338

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0DataRank · unranked

5 citations

Tomas Yeo, Davin Hong, Melanie J. Shears, Leila S. Ross, Kurt E. Ward +17 more

Covalent macrocyclic proteasome inhibitors mitigate resistance in Plasmodium falciparum

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.03.547579

N/A

0DataRank · unranked

0 citations

Kurt E. Ward, Ryan T. Muir, Stephanie Kabeche, Euna Yoo, Tomas Yeo +11 more

Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance

Science(2024)10.1126/science.adk9893

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0DataRank · unranked

26 citations

Karla P. Godinez‐Macias, Daisy Chen, John Okombo, Vandana Thathy, Xiu Cheng +43 more

Plasmodium falciparum African PfCRT Mutant Isoforms Conducive to Piperaquine Resistance Are Infrequent and Impart a Major Fitness Cost

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae617

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0DataRank · unranked

6 citations

Tomas Yeo, Kyra A. Schindler, Jin Yong Jeon, Talia S. Bloxham, Jennifer L. Small-Saunders +3 more

Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116921

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0DataRank · unranked

5 citations

W.-G. Su, William Nguyen, Katie Loi, Kate E. Jarman, Jocelyn Sietsma Penington +28 more

Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets

Cell chemical biology(2024)10.1016/j.chembiol.2024.07.006

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0DataRank · unranked

4 citations

Sunil Kumar Narwal, Stephanie Kabeche, Daniel Abegg, Vandana Thathy, Fiona Hackett +11 more

Quinoxaline-Based Anti-Schistosomal Compounds Have Potent Anti-Malarial Activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.23.590861

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0DataRank · unranked

2 citations

Gilda Padalino, Tomas Yeo, Andrea Brancale, David A. Fidock, Karl F. Hoffmann +2 more

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.11.575224

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0DataRank · unranked

0 citations

Sunil Kumar Narwal, Stephanie Kabeche, Daniel Abegg, Fiona Hackett, Tomas Yeo +10 more

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.27.615529

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0DataRank · unranked

0 citations

Sachel Mok, Tomas Yeo, Melanie J. Shears, Jin H. Jeon, Sunil Kumar Narwal +23 more

Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity

PLoS Pathogens(2025)10.1371/journal.ppat.1012216

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0DataRank · unranked

5 citations

Gilda Padalino, Edem Adika, John Okombo, Tomas Yeo, Andrea Brancale +4 more

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

Angewandte Chemie International Edition(2025)10.1002/anie.202425206

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0DataRank · unranked

6 citations

Dina Coertzen, Kathryn J. Wicht, Virginia Franco Hidalgo, Charisse Flerida A. Pasaje, Luiz C. Godoy +29 more

Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistance

Research Square(2025)10.21203/rs.3.rs-7697517/v1

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0DataRank · unranked

0 citations

John Okombo, Tolla Ndiaye, Tarrick Qahash, Igor M. R. Moura, Eva Gil‐Iturbe +24 more

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

Cell chemical biology(2020)10.1016/j.chembiol.2020.04.001

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0DataRank · unranked

91 citations

James M. Murithi, Charisse Flerida A. Pasaje, Sonja Ghidelli‐Disse, Louis Dwomoh, Megan J. Bird +26 more

Shared Binding Site but Divergent Resistance Profiles Uncover Novel Resistance Mechanisms in Plasmodium HSP90 Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.30.684657

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0DataRank · unranked

0 citations

Amanda K. Lukens, Mariana Laureano de Souza, Alex Foy, Jason Hsiao, Tolla Ndiaye +18 more

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00173

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0DataRank · unranked

47 citations

Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey I. Gerasyuto, Sreekanth Kokkonda +39 more

The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

Cell chemical biology(2021)10.1016/j.chembiol.2021.06.006

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0DataRank · unranked

30 citations

Ioanna Deni, Charisse Flerida A. Pasaje, John Okombo, Jessica L. Bridgford, Nina F. Gnädig +28 more

P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.27.428390

N/A

0DataRank · unranked

0 citations

Kelly Rubiano, Satish K. Dhingra, Sachel Mok, Judith Straimer, Nina F. Gnädig +26 more

Plasmodium falciparum K13 mutations in Africa and Asia present varying degrees of artemisinin resistance and an elevated fitness cost in African parasites

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.05.425445

N/A

0DataRank · unranked

0 citations

Kelly Rubiano, Satish K. Dhingra, Sachel Mok, Judith Straimer, Nina F. Gnädig +26 more

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

Nature Communications(2022)10.1038/s41467-022-29688-5

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0DataRank · unranked

41 citations

Patrick A.M. Jansen, Catalina Barceló, Justin Munro, Julie M.J. Verhoef, Charisse Flerida A. Pasaje +40 more

Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome

Cell chemical biology(2023)10.1016/j.chembiol.2023.03.002

N/A

0DataRank · unranked

29 citations

Barbara H. Stokes, Kurt E. Ward, Kate J. Fairhurst, Charisse Flerida A. Pasaje, Tomas Yeo +21 more