Leonard Petrucelli

Also affiliated with University of Miami, Jacksonville College, WinnMed, Mayo Clinic in Florida, Indiana University – Purdue University Indianapolis

MedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 2%percentile

3.9Author DataRank

Indexed papers

3in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 3 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium

Alzheimer s & Dementia(2020)10.1002/alz.12033

Top 8%

2.6DataRank

Top 8%169 citations

Danielle Brushaber, Jeremy A. Syrjanen, Walter K. Kremers, Julie A. Fields, Leah K. Forsberg +80 more

Papers

Driven by 99 papers — median percentile 88. Top paper: “Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium”.

Utility of the global CDR® plus NACC FTLD rating and development of scoring rules: Data from the ARTFL/LEFFTDS Consortium

Alzheimer s & Dementia(2020)10.1002/alz.12033

Top 8%

2.6DataRank

Top 8%169 citations

Danielle Brushaber, Jeremy A. Syrjanen, Walter K. Kremers, Julie A. Fields, Leah K. Forsberg +80 more

Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration

Neurology(2021)10.1212/wnl.0000000000011848

N/A

1.7DataRank · unranked

108 citations

Ping Wang, Adam M. Staffaroni, Carolin Heller, Yann Cobigo, Amy Wolf +88 more

Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort

Alzheimer s & Dementia(2020)10.1002/alz.12046

Top 16%

1.3DataRank

Top 16%45 citations

P. Wang, Katya Rascovsky, Alon Wolf, Brian S. Appleby, Jessica Bove +73 more

Poly(GR) and poly(GA) in cerebrospinal fluid as potential biomarkers for C9ORF72-ALS/FTD

Nature Communications(2022)10.1038/s41467-022-30387-4

N/A

1.1DataRank · unranked

54 citations

Denitza Raitcheva, Daniel A. Bartlett, Mercedes Prudencio, Diane McKenna‐Yasek, Catherine Douthwright +12 more

TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A

Nature(2022)10.1038/s41586-022-04424-7

N/A

0.957DataRank · unranked

589 citations

Mercedes Prudencio, Yuka Koike, Sarat C. Vatsavayai, Garam Kım, Fred Harbinski +30 more

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

Cell(2020)10.1016/j.cell.2020.01.027

N/A

0.909DataRank · unranked

427 citations

Christina E. Lee, Yari Carlomagno, Mukesh Kumar, Duc M. Duong, Hendrik Wesseling +11 more

Staging TDP-43 pathology in Alzheimer’s disease

Acta Neuropathologica(2014)10.1007/s00401-013-1211-9

N/A

0.890DataRank · unranked

377 citations

Melissa E. Murray, Jennifer L. Whitwell, Joseph E. Parisi, Leonard Petrucelli, Clifford R. Jack +3 more

TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia

Science Translational Medicine(2024)10.1126/scitranslmed.adf9735

N/A

0.889DataRank · unranked

51 citations

Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W. Todd, Ying Hao +31 more

Prognostic clinical and biological markers for amyotrophic lateral sclerosis disease progression: validation and implications for clinical trial design and analysis

EBioMedicine(2024)10.1016/j.ebiom.2024.105323

N/A

0.856DataRank · unranked

46 citations

Eric A. Macklin, Andrea Malaspina, Mary‐Louise Rogers, Eran Hornstein, Vittoria Lombardi +25 more

Cellular and pathological heterogeneity of primary tauopathies

Molecular Neurodegeneration(2021)10.1186/s13024-021-00476-x

N/A

0.819DataRank · unranked

234 citations

Shanu F. Roemer, Leonard Petrucelli, Dennis W. Dickson, Dah‐eun Chloe Chung

p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)

Cell(2021)10.1016/j.cell.2020.12.025

N/A

0.774DataRank · unranked

173 citations

Zohar Shipony, Rodrigo Lopez-Gonzalez, Lisa Nakayama, Yong‐Jie Zhang, Julien Couthouis +22 more

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

Science Translational Medicine(2024)10.1126/scitranslmed.adg7162

N/A

0.769DataRank · unranked

168 citations

Yue Qi, Anna‐Leigh Brown, Oscar G. Wilkins, Colleen Bereda, Cédric Belair +46 more

Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD

Cell Reports(2021)10.1016/j.celrep.2021.109581

N/A

0.673DataRank · unranked

88 citations

Wei Shao, Tiffany W. Todd, Jimei Tong, Mei Yue, Shunsuke Koga +9 more

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36

Neuron(2020)10.1016/j.neuron.2020.04.011

N/A

0.655DataRank · unranked

78 citations

Tania F. Gendron, Nisha Raj, María García-Murias, Anwesha Banerjee, Ryan H. Purcell +30 more

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders

Cell Reports Medicine(2022)10.1016/j.xcrm.2022.100607

N/A

0.641DataRank · unranked

71 citations

Michael G. Heckman, Launia J. White, Austin M. Veire, Otto Pedraza, Alexander R. Burch +77 more

Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation

Acta Neuropathologica Communications(2020)10.1186/s40478-020-01079-1

N/A

0.604DataRank · unranked

55 citations

Yari Carlomagno, Jonathon Sens, Silvia S. Kang, Tanner Jensen, Aishe Kurti +16 more

Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia

Acta Neuropathologica(2024)10.1007/s00401-024-02688-z

N/A

0.596DataRank · unranked

52 citations

Aaron Held, Katherine Dorfman, Joon Sung, Catherine Song, Amey S. Kavuturu +9 more

ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion

Nature Methods(2022)10.1038/s41592-022-01458-7

N/A

0.590DataRank · unranked

50 citations

Maxwell A. Bertolero, Sudipto Dolui, Matthew Cieslak, Kristin Murtha, Erica B. Baller +94 more

Tau and neurofilament light‐chain as fluid biomarkers in spinocerebellar ataxia type 3

European Journal of Neurology(2022)10.1111/ene.15373

N/A

0.590DataRank · unranked

50 citations

Mercedes Prudencio, Gilbert Thomas‐Black, Nita Solanky, Karen Jansen‐West, Rana Hanna Al‐Shaikh +22 more

Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.01.23.525149

N/A

0.550DataRank · unranked

38 citations

Yue Qi, Anna‐Leigh Brown, Oscar G. Wilkins, Colleen Bereda, Cédric Belair +41 more

Cryo-EM structures of pathogenic fibrils and their impact on neurodegenerative disease research

Neuron(2024)10.1016/j.neuron.2024.05.012

N/A

0.524DataRank · unranked

32 citations

Naeyma N. Islam, Casey Cook, Thomas R. Caulfield, Leonard Petrucelli, Tiffany W. Todd

Long-read targeted sequencing uncovers clinicopathological associations forC9orf72-linked diseases

Brain(2021)10.1093/brain/awab006

N/A

0.524DataRank · unranked

32 citations

Ross A. Aleff, Jazmyne L. Jackson, NiCole A. Finch, Matthew Baker, Tania F. Gendron +17 more

Evidence of cerebellar TDP-43 loss of function in FTLD-TDP

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01408-6

N/A

0.500DataRank · unranked

27 citations

Tania F. Gendron, Yuka Koike, Mei Yue, Yuping Song, Jennifer M. Kachergus +14 more

A blood–brain penetrant RNA-targeted small molecule triggers elimination of r(G 4 C 2 ) exp in c9ALS/FTD via the nuclear RNA exosome

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2210532119

N/A

0.477DataRank · unranked

23 citations

Samantha M. Meyer, Rita Fuerst, Yuquan Tong, Yue Li, Raphael I. Benhamou +11 more

Shared brain transcriptomic signature in TDP-43 type A FTLD patients with or without GRN mutations

Brain(2021)10.1093/brain/awab437

N/A

0.464DataRank · unranked

21 citations

Ligia Mateiu, Matthew Baker, Mariely DeJesus‐Hernandez, Cristina T. Vicente, NiCole A. Finch +15 more

TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD

Nature Neuroscience(2025)10.1038/s41593-025-02096-w

N/A

0.442DataRank · unranked

18 citations

Kelly A. Marshall, Peter Harley, Jacob R. Mann, Francesco Alessandrini, Carlos G. Vanoye +32 more

TDP-43-associated atrophy in brains with and without frontotemporal lobar degeneration

NeuroImage Clinical(2022)10.1016/j.nicl.2022.102954

N/A

0.425DataRank · unranked

16 citations

Peter R. Martin, Nirubol Tosakulwong, Melissa E. Murray, Leonard Petrucelli, Matthew L. Senjem +11 more

Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2123487119

N/A

0.360DataRank · unranked

10 citations

Kevin D. Meyer, Marián Hruška-Plocháň, Ricardos Tabet, Chao-Zong Lee, Ananya Ray-Soni +39 more

TDP-43 pathology induces CD8 + T cell activation through cryptic epitope recognition

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.22.660773

N/A

0.346DataRank · unranked

8 citations

Matteo Zanovello, Steven Lingyang Kong, Vidur J. Saigal, Anna‐Leigh Brown, Valentina Turchetti +34 more

ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.12.571327

N/A

0.312DataRank · unranked

7 citations

Cory A. Weller, Syed Nisar Hussain Shah, Nicholas L. Johnson, Ying Hao, Jessica Roberts +15 more

Aβ Puts the Alpha in Synuclein

Neuron(2020)10.1016/j.neuron.2020.01.001

N/A

0.292DataRank · unranked

6 citations

Leonard Petrucelli, Casey Cook

Endolysosomal dysfunction impairs proteostasis and induces neurodegeneration in vivo

iScience(2025)10.1016/j.isci.2025.113460

N/A

0.165DataRank · unranked

2 citations

Ellen A. Albagli, Karen Jansen‐West, Lillian M. Daughrity, Jimei Tong, Anxhela Hysi +17 more

Methylome analysis of FTLD patients with TDP-43 pathology identifies epigenetic signatures specific to pathological subtypes

Molecular Neurodegeneration(2025)10.1186/s13024-025-00869-2

N/A

0.104DataRank · unranked

1 citations

Tejasvi Niranjan, Elise Coopman, Júlia Faura, Sara Alidadiani, Claudia Schrauwen +44 more

The endolysosomal pathway and ALS/FTD

Trends in Neurosciences(2023)10.1016/j.tins.2023.09.004

N/A

0DataRank · unranked

38 citations

Wei Shao, Yong‐Jie Zhang, Leonard Petrucelli, Tiffany W. Todd

Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia

Neuron(2023)10.1016/j.neuron.2022.12.027

N/A

0DataRank · unranked

30 citations

Huihui Dai, So Yoen Choi, Karen Jansen‐West, Alexis S. Zajicek, Luke Daly +4 more

Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions

Cell Reports(2023)10.1016/j.celrep.2023.112822

N/A

0DataRank · unranked

28 citations

Yanwei Wu, Wei Shao, Tania F. Gendron, Sophie J. F. van der Spek, Grigorii Sultanakhmetov +20 more

CRISPR interference to evaluate modifiers of C9ORF72-mediated toxicity in FTD

Frontiers in Cell and Developmental Biology(2023)10.3389/fcell.2023.1251551

N/A

0DataRank · unranked

3 citations

Desiree Zanetti Alepuz, Yuka Koike, Mei Yue, Jimei Tong, Pinghu Liu +17 more

Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old

Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad105

N/A

0DataRank · unranked

8 citations

Hiroaki Sekiya, Shunsuke Koga, Rodolfo G. Gatto, Monica Castanedes Casey, Nha Trang Thu Pham +11 more

Investigating the Pathogenic Interplay of Alpha-Synuclein, Tau, and Amyloid Beta in Lewy Body Dementia: Insights from Viral-Mediated Overexpression in Transgenic Mouse Models

Biomedicines(2023)10.3390/biomedicines11102863

N/A

0DataRank · unranked

4 citations

Suelen L. Boschen, Aishe Kurti, Monica Castanedes Casey, Virginia Phillips, John Denis Fryer +6 more

First families with spinocerebellar ataxia type 7 in Poland

Neurologia i Neurochirurgia Polska(2023)10.5603/pjnns.a2023.0037

N/A

0DataRank · unranked

3 citations

Rana Hanna Al‐Shaikh, Mercedes Prudencio, Leonard Petrucelli, Anna Sułek, Krzysztof Bernatowicz +3 more

Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.07.544135

N/A

0DataRank · unranked

4 citations

Indranil Malik, Xiexiong Deng, Amy Krans, Karen Jansen‐West, Elizabeth M.H. Tank +6 more

Inflammasome mediated neuronal-microglial crosstalk: a therapeutic substrate of the familial C9orf72 variant of frontotemporal dementia/amyotrophic lateral sclerosis

Research Square(2023)10.21203/rs.3.rs-2420211/v1

N/A

0DataRank · unranked

0 citations

Chad Smith, Eun‐Jeong Yang, Ruth Iban‐Arias, Tatsunori Oguchi, Maria Sebastian-Valverde +10 more

HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases

Molecular Neurodegeneration(2024)10.1186/s13024-024-00718-8

N/A

0DataRank · unranked

29 citations

Lillian M. Daughrity, Ellen A. Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen‐West +20 more

Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats

Nucleic Acids Research(2024)10.1093/nar/gkae137

N/A

0DataRank · unranked

20 citations

Amy Krans, Indranil Malik, Xiexiong Deng, Evrim Yildirim, Sinem Ovunc +9 more

Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion

Acta Neuropathologica(2024)10.1007/s00401-024-02720-2

N/A

0DataRank · unranked

8 citations

Mariely DeJesus‐Hernandez, Shulan Tian, Sofia Pereira das Neves, Richard Crook, NiCole A. Finch +15 more

ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics

Genomics Proteomics & Bioinformatics(2024)10.1093/gpbjnl/qzae083

N/A

0DataRank · unranked

8 citations

Cory A. Weller, Syed Islamuddin Shah, Nicholas L. Johnson, Ying Hao, Paige Jarreau +19 more

Gene-Specific Effects on Brain Volume and Cognition of TMEM106B in Frontotemporal Lobar Degeneration

Neurology(2024)10.1212/wnl.0000000000209832

N/A

0DataRank · unranked

7 citations

Eliana Marisa Ramos, Nick Corriveau‐Lecavalier, Vijay K. Ramanan, John Kornak, Carly Mester +50 more

Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43

PLoS ONE(2024)10.1371/journal.pone.0298080

N/A

0DataRank · unranked

6 citations

Tiffany W. Todd, Wei Shao, Caroline J. Jones, Kexin Huang, Lillian M. Daughrity +9 more

TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.22.575730

N/A

0DataRank · unranked

25 citations

Anastasiia Lovchykova, Tetsuya Akiyama, Chang Liu, Caiwei Guo, Vidhya Maheswari Jawahar +7 more

Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration

Research Square(2024)10.21203/rs.3.rs-4103685/v1

N/A

0DataRank · unranked

8 citations

Adam M. Staffaroni, Eric B. Dammer, Erik C. B. Johnson, Emily W. Paolillo, Amy B. Wise +63 more

Symptomatic progression of frontotemporal dementia with the TARDBP I383V variant

Neurocase(2024)10.1080/13554794.2024.2354540

N/A

0DataRank · unranked

0 citations

D. Carter, Eliana Marisa Ramos, Joie Molden, Kaitlin Smith, Francesca Dino +16 more

Studying C9orf72 dipeptide repeat polypeptide aggregation using an analytical ultracentrifuge equipped with fluorescence detection

Analytical Biochemistry(2024)10.1016/j.ab.2024.115720

N/A

0DataRank · unranked

0 citations

Nicole R. Cunningham, Jeanne M. Quinn, Danielle R. Jacobsen, F. Jay Garcia, S. Galindo +5 more

TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

Nature Neuroscience(2025)10.1038/s41593-025-02049-3

N/A

0DataRank · unranked

29 citations

Anastasiia Lovchykova, Tetsuya Akiyama, Stephanie L. Rayner, Vidhya Bharathi, Chang Liu +8 more

TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in amyotrophic lateral sclerosis and frontotemporal dementia

Journal of Clinical Investigation(2025)10.1172/jci182088

N/A

0DataRank · unranked

24 citations

Ya Cui, Sebastian Michels, Michael R. Colwin, Cameron Stockford, Wenbin Ye +19 more

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders

Molecular Neurodegeneration(2025)10.1186/s13024-025-00821-4

N/A

0DataRank · unranked

19 citations

Linn Öijerstedt, Michael G. Heckman, Launia J. White, Hilary W. Heuer, Argentina Lario Lago +37 more

Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS

Cell(2025)10.1016/j.cell.2025.07.045

N/A

0DataRank · unranked

9 citations

Mingee Chung, Sabrina A. Stratton, Chang Hee Han, Woo Jae Kim, Udit Sheth +28 more

TDP‐43 Cryptic RNAs in Perry Syndrome: Differences across Brain Regions and TDP‐43 Proteinopathies

Movement Disorders(2025)10.1002/mds.30104

N/A

0DataRank · unranked

11 citations

Jesús González Bejarano, Anand Narayan, Lillian M. Daughrity, Candela Maroto Cidfuentes, Madison M. Reeves +18 more

Evaluating Glial Fibrillary Acidic Protein and Neurofilament Light as Potential Biomarkers for Spinocerebellar Ataxia 7

International Journal of Molecular Sciences(2025)10.3390/ijms26115070

N/A

0DataRank · unranked

6 citations

Karen Jansen‐West, Audrey Strongosky, Zoe Parrales, Judith A. Dunmore, Yuping Song +9 more

Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers

Annals of Clinical and Translational Neurology(2025)10.1002/acn3.70170

N/A

0DataRank · unranked

2 citations

Stephanie A. Chu, Suvi Häkkinen, Liwen Zhang, David McFall, Jonathan D. Rohrer +41 more

CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice

Science Translational Medicine(2025)10.1126/scitranslmed.adq3551

N/A

0DataRank · unranked

3 citations

Xiying Wang, Jie Pan, Danish Khan, Sopida Pimcharoen, Yong‐Jie Zhang +7 more

Integrative multiomic analysis links TDP-43-driven splicing defects to cascading proteomic disruption of ALS/FTD pathways

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.29.679403

N/A

0DataRank · unranked

2 citations

Zhengde Liu, Keyana Blake, Yue Qi, Sasha Rollinson, Sahba Seddighi +13 more

U7 small nuclear RNA splice-switching therapeutics for STMN2 and UNC13A in Amyotrophic Lateral Sclerosis

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.11.26.690143

N/A

0DataRank · unranked

1 citations

Travis E. Solomon, Sarah Pickles, Peter Harley, Michela Barioglio, Christoph Schweingruber +16 more

Cryptic intronic transcriptional initiation generates efficient endogenous mRNA templates for C9orf72-associated RAN translation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.27.650888

N/A

0DataRank · unranked

0 citations

Katelyn M. Green, Bradley Crone, Jessica A. Switzenberg, Elizabeth M.H. Tank, Amy Krans +8 more

Targeted plasma proteomics uncover novel proteins associated with KIF5A -linked SPG10 and ALS spectrum disorders

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.29.651203

N/A

0DataRank · unranked

0 citations

Arun K. Boddapati, Barbara Risi, Pablo Iruzubieta, Antonio Orlacchio, Roberto Fernández‐Torrón +14 more

Targeted plasma proteomics uncover proteins associated with KIF5A-linked SPG10 and ALS spectrum disorders

Human Genetics and Genomics Advances(2025)10.1016/j.xhgg.2025.100498

N/A

0DataRank · unranked

0 citations

Arun K. Boddapati, Barbara Risi, Pablo Iruzubieta, Antonio Orlacchio, Roberto Fernández‐Torrón +15 more

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony-Stimulating Factor-1 Receptor-Related Disorders

medRxiv(2025)10.1101/2025.09.12.25335644

N/A

0DataRank · unranked

0 citations

Madison Reeves, Karen Jansen‐West, Judith A. Dunmore, Yuping Song, Audrey Strongosky +9 more

Analysis of the splicing landscape of the frontal cortex in FTLD-TDP reveals subtype specific patterns and cryptic splicing

Acta Neuropathologica(2025)10.1007/s00401-025-02901-7

N/A

0DataRank · unranked

6 citations

Bavo Heeman, Cyril Pottier, Matthew Baker, Mariely DeJesus‐Hernandez, Fahri Küçükali +23 more

Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

Journal of Clinical Investigation(2020)10.1172/jci139741

N/A

0DataRank · unranked

258 citations

Jack Humphrey, Sarah Pickles, Anna‐Leigh Brown, Sarah E. Hill, Jennifer M. Kachergus +47 more

Reduced C9ORF72 function exacerbates gain of toxicity from ALS/FTD-causing repeat expansion in C9orf72

Nature Neuroscience(2020)10.1038/s41593-020-0619-5

N/A

0DataRank · unranked

235 citations

Jie Jiang, Tania F. Gendron, Melissa McAlonis‐Downes, Lu-Lin Jiang, Amy E. Taylor +13 more

Plasma neurofilament light predicts mortality in patients with stroke

Science Translational Medicine(2020)10.1126/scitranslmed.aay1913

N/A

0DataRank · unranked

93 citations

Mohammed K. Badi, Michael G. Heckman, Karen Jansen‐West, George K. Vilanilam, Patrick W. Johnson +16 more

Astrocyte-derived clusterin suppresses amyloid formation in vivo

Molecular Neurodegeneration(2020)10.1186/s13024-020-00416-1

N/A

0DataRank · unranked

68 citations

Jonathon Sens, Silvia S. Kang, Kelsey E. Baker, Taylor J. Berry, Aishe Kurti +8 more

Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers

Molecular Neurodegeneration(2020)10.1186/s13024-020-0359-8

N/A

0DataRank · unranked

53 citations

NiCole A. Finch, Matthew Baker, Jennifer M. Kachergus, Mariely DeJesus‐Hernandez, K.L. Pereira +11 more

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

Cell Reports(2020)10.1016/j.celrep.2020.107616

N/A

0DataRank · unranked

48 citations

Zachary T. McEachin, Jeannie Chew, Alexander R. Burch, Karen Jansen‐West, Jimei Tong +18 more

Structural Features of Small Molecules Targeting the RNA Repeat Expansion That Causes Genetically Defined ALS/FTD

ACS Chemical Biology(2020)10.1021/acschembio.0c00049

N/A

0DataRank · unranked

20 citations

Kye Won Wang, Jessica A. Bush, Shruti Choudhary, Jonathan L. Chen, Jared T. Baisden +6 more

Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

Molecular Neurodegeneration(2020)10.1186/s13024-020-00369-5

N/A

0DataRank · unranked

33 citations

Alireza Baradaran‐Heravi, Aruna D. Balgi, Xiujuan Wu, Tyler D. Yan, Steve Arns +12 more

A Complex Containing HNRNPA2B1 and N 6 -methyladenosine Modified Transcripts Mediates Actions of Toxic Tau Oligomers

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.12.03.409334

N/A

0DataRank · unranked

0 citations

Weiwei Lin, Cheng Zhang, Mamta Verma, Julian Kwan, Emily van Vliet +16 more

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

UNC Libraries(2020)10.17615/6qag-q019

N/A

0DataRank · unranked

0 citations

Adeela Kamal, Dennis W. Dickson, Francis Burrows, N. Stanley Nahman, Natalia Klosak +11 more

CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity

UNC Libraries(2020)10.17615/cxmw-2656

N/A

0DataRank · unranked

0 citations

Christopher A. Ross, Haibing Jiang, Leonard Petrucelli, Cam Patterson, Rachel Bailey +9 more

Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy

Molecular Cell(2021)10.1016/j.molcel.2021.07.038

N/A

0DataRank · unranked

194 citations

Weiwei Lin, Cheng Zhang, Peter E.A. Ash, Mamta Verma, Julian Kwan +21 more

TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2014188118

N/A

0DataRank · unranked

161 citations

Shuwen Lei, Jenifer E. Shattuck, Samantha Boudeau, Yari Carlomagno, Maria Medalla +12 more

Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19

Science Translational Medicine(2021)10.1126/scitranslmed.abi7643

N/A

0DataRank · unranked

84 citations

Young Erben, Christopher P. Marquez, Karen Jansen‐West, Camila Franco-Mesa, Michael G. Heckman +16 more

Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G 4 C 2 ) repeat expansion in vitro and in vivo ALS models

Science Translational Medicine(2021)10.1126/scitranslmed.abd5991

N/A

0DataRank · unranked

80 citations

Haruo Aikawa, Rita Fuerst, Yue Li, Andrei Ursu, Samantha M. Meyer +19 more

The AD tau core spontaneously self-assembles and recruits full-length tau to filaments

Cell Reports(2021)10.1016/j.celrep.2021.108843

N/A

0DataRank · unranked

59 citations

Sireesha Manne, Michael DeTure, Mercedes Prudencio, Yong‐Jie Zhang, Rana Hanna Al‐Shaikh +12 more

Deep vein thrombosis and pulmonary embolism among hospitalized coronavirus disease 2019–positive patients predicted for higher mortality and prolonged intensive care unit and hospital stays in a multisite healthcare system

Journal of Vascular Surgery Venous and Lymphatic Disorders(2021)10.1016/j.jvsv.2021.03.009

N/A

0DataRank · unranked

47 citations

Camila Franco-Mesa, Péter Gloviczki, William M. Stone, Alfredo Quinones-Hinojoas, Andrew J. Meltzer +30 more

A Small Molecule Exploits Hidden Structural Features within the RNA Repeat Expansion That Causes c9ALS/FTD and Rescues Pathological Hallmarks

ACS Chemical Neuroscience(2021)10.1021/acschemneuro.1c00470

N/A

0DataRank · unranked

24 citations

Jared T. Baisden, Jessica A. Bush, Amirhossein Taghavi, Shruti Choudhary, Yong‐Jie Zhang +5 more

Application of a bioinformatic pipeline to RNA-seq data identifies novel virus-like sequence in human blood

G3 Genes Genomes Genetics(2021)10.1093/g3journal/jkab141

N/A

0DataRank · unranked

8 citations

Patrick Gonzales, Thomas J. LaRocca, Yuping Song, Joanne Wuu, Michael Benatar +6 more

TDP-43 represses cryptic exon inclusion in FTD/ALS gene UNC13A

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.02.438213

N/A

0DataRank · unranked

20 citations

Mercedes Prudencio, Yuka Koike, Sarat C. Vatsavayai, Garam Kım, Fred Harbinski +22 more

Deletion of the Ubiquitin Ligase CHIP Leads to the Accumulation, But Not the Aggregation, of Both Endogenous Phospho- and Caspase-3-Cleaved Tau Species

UNC Libraries(2021)10.17615/vm3k-rq43

N/A

0DataRank · unranked

0 citations

Mei Yue, Christopher B. Eckman, Judith Dunmore, Chris W. Lee, Dennis W. Dickson +11 more

Temporal order of clinical and biomarker changes in familial frontotemporal dementia

Nature Medicine(2022)10.1038/s41591-022-01942-9

N/A

0DataRank · unranked

138 citations

Melanie Quintana, Barbara Wendelberger, Hilary W. Heuer, Lucy L. Russell, Yann Cobigo +95 more

Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy

Molecular Neurodegeneration(2022)10.1186/s13024-022-00585-1

N/A

0DataRank · unranked

48 citations

Deepak Chhangani, Melissa C. Wren, Courtney L. Smith, Jannifer H. Lee, Xingli Li +23 more

Cracking the cryptic code in amyotrophic lateral sclerosis and frontotemporal dementia: Towards therapeutic targets and biomarkers

Clinical and Translational Medicine(2022)10.1002/ctm2.818

N/A

0DataRank · unranked

28 citations

Yuka Koike, Leonard Petrucelli, Aaron D. Gitler, Tetsuya Akiyama

Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins

Science Translational Medicine(2022)10.1126/scitranslmed.abq3215

N/A

0DataRank · unranked

23 citations

Quinlan T. Mewborne, Amandeep Girdhar, Udit Sheth, Alyssa N. Coyne, Ritika Punathil +23 more

Plasma PolyQ-ATXN3 Levels Associate With Cerebellar Degeneration and Behavioral Abnormalities in a New AAV-Based SCA3 Mouse Model

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.863089

N/A

0DataRank · unranked

13 citations

Tiffany W. Todd, Lillian M. Daughrity, Mei Yue, Jimei Tong, Yari Carlomagno +11 more

Race affects adverse outcomes of deep vein thrombosis, pulmonary embolism, and acute kidney injury in coronavirus disease 2019 hospitalized patients

Journal of Vascular Surgery Venous and Lymphatic Disorders(2022)10.1016/j.jvsv.2022.05.019

N/A

0DataRank · unranked

7 citations

Christopher P. Marquez, Mercedes Prudencio, Susana Fortich, Tania Gendron, Devang Sanghavi +8 more

HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2021.809942

N/A

0DataRank · unranked

6 citations

Yari Carlomagno, Tiffany W. Todd, Caroline Y. Jones, Mercedes Prudencio, Lillian M. Daughrity +16 more

Comprehensive preclinical evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9ORF72 disease

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.13.475329

N/A

0DataRank · unranked

0 citations

Kevin D. Meyer, Marián Hruška-Plocháň, Ricardos Tabet, Chao-Zong Lee, Ananya Ray-Soni +39 more

Microglial REV-ERBα regulates inflammation and lipid droplet formation to drive tauopathy in male mice

Nature Communications(2023)10.1038/s41467-023-40927-1

N/A

0DataRank · unranked

80 citations

Julie Dimitry, Jong Hee Song, Minsoo Son, Patrick W. Sheehan, Melvin W. King +6 more

TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A

PLoS Biology(2023)10.1371/journal.pbio.3002028

N/A

0DataRank · unranked

75 citations

Sarah Pickles, Virginia Estades Ayuso, Karen Jansen‐West, Yue Qi, Ziyi Li +9 more

TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

Molecular Neurodegeneration(2023)10.1186/s13024-023-00646-z

N/A

0DataRank · unranked

62 citations

Sarah Pickles, Tiffany W. Todd, Mei Yue, Karen Jansen‐West, Yuping Song +12 more

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