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Assessment of biased agonism at the A3 adenosine receptor using β-arrestin and miniGαi recruitment assays

Biochemical Pharmacology(2020)10.1016/j.bcp.2020.113934Source: DataRank Database

Assessment of biased agonism at the A3 adenosine receptor using β-arrestin and miniGαi recruitment assays is a research paper published in Biochemical Pharmacology (2020). On theSindex it has a DataRank of 0. It has been cited 43 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access43 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 2.94)OA: bronzeTopics (68)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Dilip K. Tosh ORCID,Zhan‐Guo Gao ORCID,Kenneth A. Jacobson ORCID,Christophe P. Stove ORCID,Eline Pottie ORCID

Live enrichment

PubMed:32224136 PMC:PMC7382964 OpenAlex:https://openalex.org/W3013047209

Intramural NIH HHS

Grant: Z01 DK031117

Intramural NIH HHS

Grant: Z99 DK999999

Intramural NIH HHS

Grant: ZIA DK031117

National Institutes of Health

Grant: 1ZIADK031117-26

Development Of Drugs Acting At Adenosine Receptors

Fonds Wetenschappelijk Onderzoek

National Institute of Diabetes and Digestive and Kidney Diseases

FWCI

2.94

Citation Percentile

0.9%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

bronzeLicense: Elsevier TDM

journalhttps://ars.els-cdn.com/content/image/1-s2.0-S0006295220301623-ga1_lrg.jpg

publisherhttps://ars.els-cdn.com/content/image/1-s2.0-S0006295220301623-ga1_lrg.jpg

publisherhttps://api.elsevier.com/content/article/PII:S0006295220301623?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0006295220301623?httpAccept=text/plain

journalhttps://doi.org/10.1016/j.bcp.2020.113934

Fields of Study

Adenosine and Purinergic SignalingReceptor Mechanisms and SignalingPharmacological Receptor Mechanisms and Effects0301 basic medicine0303 health sciences03 medical and health sciencesAdenosineAdenosine A3 Receptor AgonistsDrug Evaluation, PreclinicalFlow CytometryGTP-Binding Protein alpha SubunitsHEK293 CellsHumansLigandsLuminescent MeasurementsReceptor, Adenosine A3Signal TransductionStructure-Activity RelationshipTransduction, GeneticTransfectionbeta-Arrestin 2

MeSH Terms

beta-Arrestin 2AdenosineDrug Evaluation, PreclinicalFlow CytometryHumansLigandsLuminescent MeasurementsStructure-Activity RelationshipTransduction, GeneticTransfectionSignal TransductionReceptor, Adenosine A3GTP-Binding Protein alpha SubunitsHEK293 CellsAdenosine A3 Receptor Agonists

Keywords

BioassayReceptorG protein-coupled receptorPharmacologyBiologyProtein-fragment complementation assayAdenosine receptorComputational biologyChemistryComplementationBiochemistryAgonistPhenotypeGeneticsStructure-activity relationshipBiased SignalingA(3) Adenosine ReceptorΒ-arrestin2AdenosineReceptor, Adenosine A3Drug Evaluation, PreclinicalFlow CytometryLigandsTransfectionbeta-Arrestin 2GTP-Binding Protein alpha SubunitsHEK293 CellsAdenosine A3 Receptor AgonistsTransduction, GeneticLuminescent MeasurementsHumansSignal Transduction

Sustainable Development Goals

SDG 0: Good health and well-being