David A. Fidock

Also affiliated with Institut Pasteur, University of Dallas, Columbia University Irving Medical Center, Office of Infectious Diseases, CNR de la Résistance aux Antibiotiques, Division of Parasitic Diseases and Malaria, Columbia University

MedicineComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Papers

Driven by 74 papers. Top paper: “Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea”.

Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea

New England Journal of Medicine(2023)10.1056/nejmoa2210956

N/A

5.4DataRank · unranked

206 citations

Lucien Platon, Araia Berhane, Barbara H. Stokes, Marian Warsame, Pascal Campagne +11 more

A Phase 1, Placebo-controlled, Randomized, Single Ascending Dose Study and a Volunteer Infection Study to Characterize the Safety, Pharmacokinetics, and Antimalarial Activity of the Plasmodium Phosphatidylinositol 4-Kinase Inhibitor MMV390048

Clinical Infectious Diseases(2020)10.1093/cid/ciaa368

N/A

1.6DataRank · unranked

56 citations

Cristina Donini, Stephan Chalon, John Woodford, Louise Marquart, Katharine A. Collins +6 more

Emergence and clonal expansion of in vitro artemisinin-resistant Plasmodium falciparum kelch13 R561H mutant parasites in Rwanda

Nature Medicine(2020)10.1038/s41591-020-1005-2

N/A

1.0DataRank · unranked

865 citations

Eric Legrand, Barbara H. Stokes, Jean-Louis Mangala Ndikumana, Marian Warsame, Noella Umulisa +13 more

Molecular Mechanisms of Drug Resistance in Plasmodium falciparum Malaria

Annual Review of Microbiology(2020)10.1146/annurev-micro-020518-115546

N/A

0.869DataRank · unranked

328 citations

Sachel Mok, David A. Fidock, Kathryn J. Wicht

Antimalarial drug discovery: progress and approaches

Nature Reviews Drug Discovery(2023)10.1038/s41573-023-00772-9

N/A

0.818DataRank · unranked

232 citations

Kathryn J. Wicht, Kelly Chibale, Jeremy N. Burrows, David A. Fidock, Elizabeth A. Winzeler +1 more

Artemisia annua L. extracts inhibit the in vitro replication of SARS-CoV-2 and two of its variants

Journal of Ethnopharmacology(2021)10.1016/j.jep.2021.114016

N/A

0.727DataRank · unranked

126 citations

Yiming Huang, David A. Fidock, Stephen J. Polyak, Jessica Wagoner, Melissa J. Towler +2 more

A G358S mutation in the Plasmodium falciparum Na+ pump PfATP4 confers clinically-relevant resistance to cipargamin

Nature Communications(2022)10.1038/s41467-022-33403-9

N/A

0.624DataRank · unranked

63 citations

Jinxin V. Pei, James E. O. Rosling, Vandana Thathy, Dongdi Li, Yi Xue +26 more

Mutation in the Plasmodium falciparum BTB/POZ Domain of K13 Protein Confers Artemisinin Resistance

Antimicrobial Agents and Chemotherapy(2021)10.1128/aac.01320-21

N/A

0.538DataRank · unranked

35 citations

Romain Coppée, Barbara H. Stokes, Nina F. Gnädig, Karamoko Niaré, Jean-Michel Augereau +4 more

Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

Nature Communications(2023)10.1038/s41467-023-36921-2

N/A

0.524DataRank · unranked

32 citations

Charisse Flerida A. Pasaje, Robert L. Summers, Pamela Magistrado-Coxen, Kyra A. Schindler, Victoriano Corpas‐López +25 more

Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages

PLoS Pathogens(2022)10.1371/journal.ppat.1010926

N/A

0.515DataRank · unranked

30 citations

Sachel Mok, Tarrick Qahash, Tomas Yeo, Jade Bath, Lindsey Orchard +6 more

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

Science Advances(2023)10.1126/sciadv.adi2364

N/A

0.510DataRank · unranked

29 citations

Tomas Yeo, Davin Hong, Melanie J. Shears, Leila S. Ross, Kurt E. Ward +19 more

Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites

Scientific Reports(2021)10.1038/s41598-021-81486-z

N/A

0.489DataRank · unranked

25 citations

Richard T. Eastman, Kathryn J. Wicht, Daniel J. Jansen, Daniel C. Talley, Benjamin A. Sigmon +25 more

Covalent Macrocyclic Proteasome Inhibitors Mitigate Resistance in Plasmodium falciparum

ACS Infectious Diseases(2023)10.1021/acsinfecdis.3c00310

N/A

0.477DataRank · unranked

13 citations

Kurt E. Ward, Ryan K. Muir, Stephanie Kabeche, Euna Yoo, Tomas Yeo +11 more

Identification of potent and reversible piperidine carboxamides that are species-selective orally active proteasome inhibitors to treat malaria

Cell chemical biology(2024)10.1016/j.chembiol.2024.07.001

N/A

0.425DataRank · unranked

16 citations

Suraksha Gahalawat, S. Ray, Nhi Ho, Yan Han, Kurt E. Ward +29 more

Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission

Science Advances(2024)10.1126/sciadv.adq1383

N/A

0.241DataRank · unranked

4 citations

Antima Gupta, Laura Drought, Avnish Patel, John Okombo, Mariëtte van der Watt +42 more

A recombinant expression system for the Plasmodium falciparum proteasome enables structural analysis of its assembly and the design of selective inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.08.13.670186

N/A

0.208DataRank · unranked

3 citations

Hanxiao Zhang, Liam Urich, Elany Barbosa da Silva, Cesar Hoffmann da Silva, Jehad Almaliti +10 more

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

Research Square(2024)10.21203/rs.3.rs-5412515/v1

N/A

0.104DataRank · unranked

1 citations

Daisy Chen, John Wallis, Miles G. Siegel, Anna Adam, Selina Bopp +44 more

Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series

Journal of Medicinal Chemistry(2021)10.1021/acs.jmedchem.1c00173

N/A

0DataRank · unranked

47 citations

Xiaoyi Deng, Shawn Watts, Goran Krilov, Aleksey I. Gerasyuto, Sreekanth Kokkonda +39 more

MalDA, Accelerating Malaria Drug Discovery

Trends in Parasitology(2021)10.1016/j.pt.2021.01.009

N/A

0DataRank · unranked

118 citations

Sabine Ottilie, Eva S. Istvan, Karla P. Godinez‐Macias, Amanda K. Lukens, Beatriz Baragaña +18 more

Artemisia annua L. hot-water extracts show potent activity in vitro against Covid-19 variants including delta

Journal of Ethnopharmacology(2021)10.1016/j.jep.2021.114797

N/A

0DataRank · unranked

33 citations

Yaoxing Huang, David A. Fidock, Melissa J. Towler, Pamela J. Weathers, Manoj S. Nair

The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

Cell chemical biology(2021)10.1016/j.chembiol.2021.06.006

N/A

0DataRank · unranked

30 citations

Ioanna Deni, Charisse Flerida A. Pasaje, John Okombo, Jessica L. Bridgford, Nina F. Gnädig +28 more

Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That is Reversed by Proteasome Inhibition

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.24.256842

N/A

0DataRank · unranked

0 citations

Barbara H. Stokes, Dana Aghabi, Matt Bogyo, David A. Fidock, Andrew P. Waters +1 more

Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes

International Journal for Parasitology(2021)10.1016/j.ijpara.2020.10.011

N/A

0DataRank · unranked

18 citations

T. R. Santha Kumar, Philipp P. Henrich, Larissa Laine, Gavin Blackburn, Achuthanunni Chokkathukalam +11 more

Hemozoin Promotes Lung Inflammation via Host Epithelial Activation

mBio(2021)10.1128/mbio.02399-20

N/A

0DataRank · unranked

8 citations

David A. Fidock, Alice Prince, Shivang S. Shah

P. falciparum K13 mutations present varying degrees of artemisinin resistance and reduced fitness in African parasites

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.27.428390

N/A

0DataRank · unranked

0 citations

Kelly Rubiano, Satish K. Dhingra, Sachel Mok, Judith Straimer, Nina F. Gnädig +26 more

Plasmodium falciparum K13 mutations in Africa and Asia present varying degrees of artemisinin resistance and an elevated fitness cost in African parasites

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.01.05.425445

N/A

0DataRank · unranked

0 citations

Kelly Rubiano, Satish K. Dhingra, Sachel Mok, Judith Straimer, Nina F. Gnädig +26 more

Plasmodium falciparum resistance to artemisinin-based combination therapies

Current Opinion in Microbiology(2022)10.1016/j.mib.2022.102193

N/A

0DataRank · unranked

123 citations

David A. Fidock, Jessica L. Bridgford, Kurt E. Ward

Lipoic acid biosynthesis is essential for Plasmodium falciparum transmission and influences redox response and carbon metabolism of parasite asexual blood stages

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.17.099630

N/A

0DataRank · unranked

1 citations

T. R. Santha Kumar, Philipp P. Henrich, Larissa Laine, Gavin Blackburn, Achuthanunni Chokkathukalam +10 more

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

Nature Communications(2022)10.1038/s41467-022-29688-5

N/A

0DataRank · unranked

41 citations

Patrick A.M. Jansen, Catalina Barceló, Justin Munro, Julie M.J. Verhoef, Charisse Flerida A. Pasaje +40 more

Integrative Genetic Manipulation of Plasmodium cynomolgi Reveals Multidrug Resistance-1 Y976F Associated With Increased In Vitro Susceptibility to Mefloquine

The Journal of Infectious Diseases(2022)10.1093/infdis/jiac469

N/A

0DataRank · unranked

26 citations

Peter Christensen, Annie Racklyeft, Satish K. Dhingra, Adeline C. Y. Chua, Caroline Remmert +13 more

Mutant PfCRT Can Mediate Piperaquine Resistance in African Plasmodium falciparum With Reduced Fitness and Increased Susceptibility to Other Antimalarials

The Journal of Infectious Diseases(2022)10.1093/infdis/jiac365

N/A

0DataRank · unranked

34 citations

Jennifer L. Small-Saunders, Laura M. Hagenah, Sachel Mok, David A. Fidock, Kathryn J. Wicht

Evidence for the early emergence of piperaquine-resistant Plasmodium falciparum malaria and modeling strategies to mitigate resistance

PLoS Pathogens(2022)10.1371/journal.ppat.1010278

N/A

0DataRank · unranked

32 citations

Laura M. Hagenah, Kathryn J. Wicht, Satish K. Dhingra, Ioanna Deni, Jonathan Kim +9 more

Expansion of a Specific Plasmodium falciparum PfMDR1 Haplotype in Southeast Asia with Increased Substrate Transport

mBio(2020)10.1128/mbio.02093-20

N/A

0DataRank · unranked

35 citations

Miguel Silva, Vitória Baptista, Vandana Thathy, Rita Silva-Pedrosa, Diana Granja +5 more

Keystone Malaria Symposium 2022: a vibrant discussion of progress made and challenges ahead from drug discovery to treatment

Trends in Parasitology(2022)10.1016/j.pt.2022.06.005

N/A

0DataRank · unranked

4 citations

Laura M. Hagenah, Elizabeth A. Ashley, Kelly Chibale, David A. Fidock, Mariko Kanai

The Plasmodium falciparum protein PfMRP1 functions as an influx ABC transporter

Research Square(2022)10.21203/rs.3.rs-1210682/v1

N/A

0DataRank · unranked

2 citations

Carla Calçada, Nuno S. Osório, Vitória Baptista, Vandana Thathy, Miguel C. Teixeira +5 more

Structure-Based Screening of Plasmodium berghei Glutathione S-Transferase Identifies CB-27 as a Novel Antiplasmodial Compound

Frontiers in Pharmacology(2020)10.3389/fphar.2020.00246

N/A

0DataRank · unranked

14 citations

Daisy D. Colón-López, Joel Vega-Rodríguez, Alice Dupin, David A. Fidock, Abel Baerga‐Ortiz +4 more

Plasmodium berghei K13 Mutations Mediate In Vivo Artemisinin Resistance That Is Reversed by Proteasome Inhibition

mBio(2020)10.1128/mbio.02312-20

N/A

0DataRank · unranked

24 citations

Barbara H. Stokes, Dana Aghabi, Matt Bogyo, David A. Fidock, Andrew P. Waters +1 more

Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway

Nature Communications(2020)10.1038/s41467-020-15440-4

N/A

0DataRank · unranked

57 citations

Frances Rocamora, Danushka S. Marapana, Nina F. Gnädig, Sabine Ottilie, Madeline R. Luth +21 more

Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome

Cell chemical biology(2023)10.1016/j.chembiol.2023.03.002

N/A

0DataRank · unranked

29 citations

Barbara H. Stokes, Kurt E. Ward, Kate J. Fairhurst, Charisse Flerida A. Pasaje, Tomas Yeo +21 more

Genetic screens reveal a central role for heme metabolism in artemisinin susceptibility

Nature Communications(2020)10.1038/s41467-020-18624-0

N/A

0DataRank · unranked

77 citations

Saima Sidik, Boryana Petrova, Nina F. Gnädig, John Okombo, Alice L Herneisen +6 more

Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target

Science Translational Medicine(2023)10.1126/scitranslmed.adc9249

N/A

0DataRank · unranked

27 citations

Francisco M. Guerra, Matthew Abraham, Kuo‐Sen Huang, Frances Rocamora, Haoshuang Zhao +22 more

Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13

PLoS Pathogens(2020)10.1371/journal.ppat.1008482

N/A

0DataRank · unranked

89 citations

Barbara H. Stokes, Rachel L. Edwards, Gavreel Kalantarov, Kim C. Heimsch, Michal Kuderjavy +9 more

Determinants of piperaquine-resistant malaria in South America

The Lancet Infectious Diseases(2023)10.1016/s1473-3099(23)00564-9

N/A

0DataRank · unranked

8 citations

David A. Fidock, Sachel Mok

Mapping the genomic landscape of multidrug resistance in Plasmodium falciparum and its impact on parasite fitness

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.02.543338

N/A

0DataRank · unranked

5 citations

Tomas Yeo, Davin Hong, Melanie J. Shears, Leila S. Ross, Kurt E. Ward +17 more

Covalent macrocyclic proteasome inhibitors mitigate resistance in Plasmodium falciparum

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.07.03.547579

N/A

0DataRank · unranked

0 citations

Kurt E. Ward, Ryan T. Muir, Stephanie Kabeche, Euna Yoo, Tomas Yeo +11 more

Towards next-generation treatment options to combat Plasmodium falciparum malaria

Nature Reviews Microbiology(2024)10.1038/s41579-024-01099-x

N/A

0DataRank · unranked

49 citations

David A. Fidock, John Okombo

Urgent action is needed to confront artemisinin partial resistance in African malaria parasites

Nature Medicine(2024)10.1038/d41591-024-00028-y

N/A

0DataRank · unranked

40 citations

Roly Gosling, Rosario Martinez-Vega, Khalid B. Beshir, Jeffrey A. Bailey, John Chimumbwa +14 more

tRNA modification reprogramming contributes to artemisinin resistance in Plasmodium falciparum

Nature Microbiology(2024)10.1038/s41564-024-01664-3

N/A

0DataRank · unranked

30 citations

Ameya Sinha, Talia S. Bloxham, Laura M. Hagenah, Guangxin Sun, Peter R. Preiser +3 more

Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance

Science(2024)10.1126/science.adk9893

N/A

0DataRank · unranked

26 citations

Karla P. Godinez‐Macias, Daisy Chen, John Okombo, Vandana Thathy, Xiu Cheng +43 more

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

Cell chemical biology(2020)10.1016/j.chembiol.2020.04.001

N/A

0DataRank · unranked

91 citations

James M. Murithi, Charisse Flerida A. Pasaje, Sonja Ghidelli‐Disse, Louis Dwomoh, Megan J. Bird +26 more

A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants

PLoS Pathogens(2024)10.1371/journal.ppat.1012627

N/A

0DataRank · unranked

8 citations

Gustavo Capatti Cassiano, Luis Carlos Salazar Alvarez, John Okombo, Juliana Calit, Diana Fontinha +12 more

Plasmodium falciparum African PfCRT Mutant Isoforms Conducive to Piperaquine Resistance Are Infrequent and Impart a Major Fitness Cost

The Journal of Infectious Diseases(2024)10.1093/infdis/jiae617

N/A

0DataRank · unranked

6 citations

Tomas Yeo, Kyra A. Schindler, Jin Yong Jeon, Talia S. Bloxham, Jennifer L. Small-Saunders +3 more

Drug-induced stress mediates Plasmodium falciparum ring-stage growth arrest and reduces in vitro parasite susceptibility to artemisinin

Microbiology Spectrum(2024)10.1128/spectrum.03500-23

N/A

0DataRank · unranked

6 citations

Didier Leroy, David A. Fidock, Didier Ménard, Lucien Platon

Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b

European Journal of Medicinal Chemistry(2024)10.1016/j.ejmech.2024.116921

N/A

0DataRank · unranked

5 citations

W.-G. Su, William Nguyen, Katie Loi, Kate E. Jarman, Jocelyn Sietsma Penington +28 more

Mixed alkyl/aryl phosphonates identify metabolic serine hydrolases as antimalarial targets

Cell chemical biology(2024)10.1016/j.chembiol.2024.07.006

N/A

0DataRank · unranked

4 citations

Sunil Kumar Narwal, Stephanie Kabeche, Daniel Abegg, Vandana Thathy, Fiona Hackett +11 more

Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria

Nature(2020)10.1038/s41586-020-2220-1

N/A

0DataRank · unranked

95 citations

Alok Das Mohapatra, Anup Jnawali, Jenna Zuromski, Ambrish Jha, Gerald Cham-Kpu +28 more

Quinoxaline-Based Anti-Schistosomal Compounds Have Potent Anti-Malarial Activity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.23.590861

N/A

0DataRank · unranked

2 citations

Gilda Padalino, Tomas Yeo, Andrea Brancale, David A. Fidock, Karl F. Hoffmann +2 more

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.11.575224

N/A

0DataRank · unranked

0 citations

Sunil Kumar Narwal, Stephanie Kabeche, Daniel Abegg, Fiona Hackett, Tomas Yeo +10 more

Plasmodium falciparum quinine resistance is multifactorial and includes a role for the drug/metabolite transporters PfCRT and DMT1

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.09.27.615529

N/A

0DataRank · unranked

0 citations

Sachel Mok, Tomas Yeo, Melanie J. Shears, Jin H. Jeon, Sunil Kumar Narwal +23 more

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

npj Drug Discovery.(2025)10.1038/s44386-025-00006-5

N/A

0DataRank · unranked

11 citations

Daisy Chen, John Wallis, Miles G. Siegel, Anna Adam, Selina Bopp +44 more

Plasmodium falciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity

Cell chemical biology(2025)10.1016/j.chembiol.2025.06.003

N/A

0DataRank · unranked

9 citations

Tiantian Jiang, Lushun Wang, Monica J. Bohmer, Subhoja Chakraborty, John Okombo +32 more

Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity

PLoS Pathogens(2025)10.1371/journal.ppat.1012216

N/A

0DataRank · unranked

5 citations

Gilda Padalino, Edem Adika, John Okombo, Tomas Yeo, Andrea Brancale +4 more

Novel Inhibitors of Plasmodium Phosphatidylinositol 4-kinase IIIβ with Low Propensity for Resistance: Life Cycle Stage Activity and In Vivo Efficacy in a Humanized Mouse Malaria Infection Model

Journal of Medicinal Chemistry(2025)10.1021/acs.jmedchem.5c01417

N/A

0DataRank · unranked

3 citations

Mmakwena M. Mmonwa, Dina Coertzen, Liezl Krugmann, Nicolaas Salomane, Meta Leshabane +18 more

Identification of α-Azacyclic Acetamide-Based Inhibitors of P. falciparum Na + Pump ( Pf ATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening

ACS Infectious Diseases(2025)10.1021/acsinfecdis.5c00436

N/A

0DataRank · unranked

3 citations

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong +13 more

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

Angewandte Chemie International Edition(2025)10.1002/anie.202425206

N/A

0DataRank · unranked

6 citations

Dina Coertzen, Kathryn J. Wicht, Virginia Franco Hidalgo, Charisse Flerida A. Pasaje, Luiz C. Godoy +29 more

Gametocyte production and transmission fitness of African and Asian Plasmodium falciparum isolates with differential susceptibility to artemisinins

Antimicrobial Agents and Chemotherapy(2025)10.1128/aac.01930-24

N/A

0DataRank · unranked

1 citations

Chiara Andolina, Jordache Ramjith, Rianne Stoter, Jan C. van Gemert, Wouter Graumans +11 more

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity Against the Human Malaria Parasite Plasmodium falciparum via Polypharmacological Inhibition of Pf Ark1 and Hemozoin Formation

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.17.664511

N/A

0DataRank · unranked

4 citations

John G. Woodland, Larnelle F. Garnie, Henrico Langeveld, Dale Taylor, Luiz C. Godoy +24 more

Identification of α-azacyclic acetamide-based inhibitors of P. falciparum Na + pump ( Pf ATP4) with fast-killing asexual blood-stage antimalarial activity by phenotypic screening

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.05.20.655166

N/A

0DataRank · unranked

0 citations

Leah S. Imlay, Vandana Thathy, Kate J. Fairhurst, Adele M. Lehane, Aloysus K. Lawong +13 more

Convergent Evolution of Artemisinin and Chloroquine Resistance in Ethiopian Plasmodium falciparum Parasites

Open MIND(2025)10.12688/verixiv.1201.1

N/A

0DataRank · unranked

0 citations

Leen N. Vanheer, Mengst Engdaw, Dawit Hailu Alemayehu, Jimma Dinsa Deressa, Bethlehem Adnew +36 more

Collateral hypersensitivity between ZY19489 and piperaquine neutralizes PfCRT-mediated drug efflux and Plasmodium falciparum resistance

Research Square(2025)10.21203/rs.3.rs-7697517/v1

N/A

0DataRank · unranked

0 citations

John Okombo, Tolla Ndiaye, Tarrick Qahash, Igor M. R. Moura, Eva Gil‐Iturbe +24 more

Shared Binding Site but Divergent Resistance Profiles Uncover Novel Resistance Mechanisms in Plasmodium HSP90 Inhibitors

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.30.684657

N/A

0DataRank · unranked

0 citations

Amanda K. Lukens, Mariana Laureano de Souza, Alex Foy, Jason Hsiao, Tolla Ndiaye +18 more

Assessing risks of Plasmodium falciparum resistance to select next-generation antimalarials

Trends in Parasitology(2021)10.1016/j.pt.2021.04.006

N/A

0DataRank · unranked

118 citations

Benjamin Blasco, Jeremy N. Burrows, Timothy N. C. Wells, David A. Fidock, Didier Leroy +1 more

Local emergence in Amazonia of Plasmodium falciparum k13 C580Y mutants associated with in vitro artemisinin resistance

eLife(2020)10.7554/elife.51015

N/A

0DataRank · unranked

186 citations

Horace Cox, Angela M. Early, Sachel Mok, Yassamine Lazrek, Jeanne-Céleste Paquet +11 more

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Cell chemical biology(2021)10.1016/j.chembiol.2021.07.010

N/A

0DataRank · unranked

82 citations

Charisse Flerida A. Pasaje, João Pedro Pisco, Josefine Striepen, Madeline R. Luth, Krittikorn Kümpornsin +29 more