Suresh V. Ambudkar

Also affiliated with Cancer Institute (WIA), National Cancer Institute, Center for Cancer Research

MedicineBiochemistry, Genetics and Molecular Biology

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

2in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 2 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

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The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Data from Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database

(2023)10.1158/1535-7163.c.6531693.v1

Top 100%

0DataRank

Top 100%0 citations

Anna Maria Calcagno, Chung‐Pu Wu, Sudhir Varma, Joanna H. Shih, Min Lin +7 more

Papers

Driven by 55 papers — median percentile 0. Top paper: “Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance”.

Tivantinib, A c-Met Inhibitor in Clinical Trials, Is Susceptible to ABCG2-Mediated Drug Resistance

Cancers(2020)10.3390/cancers12010186

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45 citations

Yuqi Yang, Qiu‐Xu Teng, Jing‐Quan Wang, Zi‐Ning Lei, Jing-Qiu Wang +5 more

Sitravatinib, a Tyrosine Kinase Inhibitor, Inhibits the Transport Function of ABCG2 and Restores Sensitivity to Chemotherapy-Resistant Cancer Cells in vitro

Frontiers in Oncology(2020)10.3389/fonc.2020.00700

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41 citations

Ning Ji, Qiu‐Xu Teng, Chao‐Yun Cai, Jing‐Quan Wang, Zhuo‐Xun Wu +5 more

Licochalcone A Selectively Resensitizes ABCG2-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Drugs

Journal of Natural Products(2020)10.1021/acs.jnatprod.9b01022

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37 citations

Sabrina Lusvarghi, Sung-Han Hsiao, Te-Chun Liu, Yanqing Li, Yang-Hui Huang +3 more

Multidrug transporters: recent insights from cryo-electron microscopy-derived atomic structures and animal models

F1000Research(2020)10.12688/f1000research.21295.1

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30 citations

Robert W. Robey, Michael M. Gottesman, Suresh V. Ambudkar, Sabrina Lusvarghi

Overexpression of ABCB1 and ABCG2 contributes to reduced efficacy of the PI3K/mTOR inhibitor samotolisib (LY3023414) in cancer cell lines

Biochemical Pharmacology(2020)10.1016/j.bcp.2020.114137

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25 citations

Cheng‐Yu Hung, Sabrina Lusvarghi, Yang-Hui Huang, Pin-Jung Tseng, Tai‐Ho Hung +3 more

Faculty Opinions recommendation of The ABC exporter IrtAB imports and reduces mycobacterial siderophores.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature(2020)10.3410/f.737622951.793578545

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0 citations

Suresh V. Ambudkar

Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter

Scientific Reports(2021)10.1038/s41598-021-03500-8

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43 citations

Andrea N. Robinson, Fatima Ali-Rahmani, Lyn M. Huff, Sabrina Lusvarghi, Shahrooz Vahedi +14 more

The third-generation EGFR inhibitor almonertinib (HS-10296) resensitizes ABCB1-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs

Biochemical Pharmacology(2021)10.1016/j.bcp.2021.114516

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40 citations

Tai‐Ho Hung, Sabrina Lusvarghi, Yi-Hsuan Chu, Sung-Han Hsiao, Yang-Hui Huang +3 more

Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles

Scientific Reports(2021)10.1038/s41598-020-79892-w

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31 citations

Nathalie Guragossian, Ingrid Fátima Zattoni, Vivian Rotuno Moure, Fabiane Gomes de Moraes Rego, Sabrina Lusvarghi +13 more

Tetrahydroquinoline/4,5‐Dihydroisoxazole Molecular Hybrids as Inhibitors of Breast Cancer Resistance Protein (BCRP/ABCG2)

ChemMedChem(2021)10.1002/cmdc.202100188

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19 citations

Thales Kronenberger, Arun Kumar Tonduru, Diogo Henrique Kita, Ingrid Fátima Zattoni, Cristian C. Bernal +6 more

A new porphyrin as selective substrate-based inhibitor of breast cancer resistance protein (BCRP/ABCG2)

Chemico-Biological Interactions(2021)10.1016/j.cbi.2021.109718

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15 citations

Thales Kronenberger, Diogo Henrique Kita, Laís Danciguer Guanaes, Matheus Murmel Guimarães, Larissa de Oliveira Prado +14 more

Branebrutinib (BMS-986195), a Bruton’s Tyrosine Kinase Inhibitor, Resensitizes P-Glycoprotein-Overexpressing Multidrug-Resistant Cancer Cells to Chemotherapeutic Agents

Frontiers in Cell and Developmental Biology(2021)10.3389/fcell.2021.699571

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11 citations

Megumi Murakami, Yu‐Shan Wu, Ya-Chen Chi, Sung-Han Hsiao, Yang-Hui Huang +3 more

OTS964, a TOPK Inhibitor, Is Susceptible to ABCG2-Mediated Drug Resistance

Frontiers in Pharmacology(2021)10.3389/fphar.2021.620874

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14 citations

Zhuo‐Xun Wu, Jing‐Quan Wang, Qiu‐Xu Teng, Zi‐Ning Lei, Sabrina Lusvarghi +4 more

Polyoxovanadates as new P‐glycoprotein inhibitors: insights into the mechanism of inhibition

FEBS Letters(2021)10.1002/1873-3468.14265

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12 citations

Gisele Alves de Andrade, Juliana Morais Missina, Kahoana Postal, Viktor Kalbermatter Boell, Francielli S. Santana +11 more

Characterization of the Lipidome and Biophysical Properties of Membranes from High Five Insect Cells Expressing Mouse P-Glycoprotein

Biomolecules(2021)10.3390/biom11030426

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9 citations

Patrícia Teles Martins, Eva Bernardino, Biebele Abel, Suresh V. Ambudkar, Maria João Moreno

Use of photoimmunoconjugates to characterize ABCB1 in cancer cells

Nanophotonics(2021)10.1515/nanoph-2021-0252

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8 citations

Sabrina Lusvarghi, Suresh V. Ambudkar, Huang‐Chiao Huang, Barry J. Liang

Does the ATP‐bound EQ mutant reflect the pre‐ or post‐ATP hydrolysis state in the catalytic cycle of human P‐glycoprotein (ABCB1)?

FEBS Letters(2021)10.1002/1873-3468.14054

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10 citations

Stewart R. Durell, Suresh V. Ambudkar, Sabrina Lusvarghi

Characterization of the Lipidome and Biophysical Properties of Membranes from High Five Insect Cells Expressing Mouse P-Glycoprotein

Preprints.org(2021)10.20944/preprints202102.0204.v1

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8 citations

Patrícia A. T. Martins, Eva Bernardino, Biebele Abel, Suresh V. Ambudkar, Maria João Moreno

Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.18.431829

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3 citations

Andrea N. Robinson, Fatima Ali-Rahmani, Lyn M. Huff, Sabrina Lusvarghi, Shahrooz Vahedi +14 more

Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer

Journal of Nanobiotechnology(2022)10.1186/s12951-022-01626-z

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106 citations

Suresh V. Ambudkar, N. Rajendra Prasad, Priya Yadav

PBK/TOPK inhibitor OTS964 resistance is mediated by ABCB1-dependent transport function in cancer: in vitro and in vivo study

Molecular Cancer(2022)10.1186/s12943-022-01512-0

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14 citations

Qiu‐Xu Teng, Zhuo‐Xun Wu, Jing‐Quan Wang, Zi‐Ning Lei, Sabrina Lusvarghi +4 more

Residues forming the gating regions of asymmetric multidrug transporter Pdr5 also play roles in conformational switching and protein folding

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102689

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10 citations

Lea‐Marie Nentwig, Hadiar Rahman, Lutz Schmitt, Andrew Rudrow, Andrzej Harris +8 more

The multi-targeted tyrosine kinase inhibitor SKLB610 resensitizes ABCG2-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs

Biomedicine & Pharmacotherapy(2022)10.1016/j.biopha.2022.112922

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10 citations

Megumi Murakami, Yu‐Shan Wu, Chun‐Ling Lin, Yanqing Li, Yang-Hui Huang +3 more

ABCB1 limits the cytotoxic activity of TAK-243, an inhibitor of the ubiquitin-activating enzyme UBA1

Frontiers in Bioscience-Landmark(2022)10.31083/j.fbl2701005

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9 citations

Yuqi Yang, Zi‐Ning Lei, Silpa Narayanan, Jing‐Quan Wang, Qiu‐Xu Teng +5 more

Interaction of A3 adenosine receptor ligands with the human multidrug transporter ABCG2

European Journal of Medicinal Chemistry(2022)10.1016/j.ejmech.2022.114103

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8 citations

Megumi Murakami, Dilip K. Tosh, Jinha Yu, Sabrina Lusvarghi, Ryan G. Campbell +4 more

Hydroxygenkwanin Improves the Efficacy of Cytotoxic Drugs in ABCG2-Overexpressing Multidrug-Resistant Cancer Cells

International Journal of Molecular Sciences(2022)10.3390/ijms232112763

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2 citations

Megumi Murakami, Yang-Hui Huang, Tai‐Ho Hung, Shun-Ping Wang, Yu‐Shan Wu +3 more

Natural medicinal compounds target signal transduction pathways to overcome ABC drug efflux transporter-mediated multidrug resistance in cancer

Drug Resistance Updates(2023)10.1016/j.drup.2023.101004

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77 citations

Priya Yadav, Andaleeb Sajid, Suresh V. Ambudkar, N. Rajendra Prasad, Pradhapsingh Bharathiraja

Furmonertinib, a Third-Generation EGFR Tyrosine Kinase Inhibitor, Overcomes Multidrug Resistance through Inhibiting ABCB1 and ABCG2 in Cancer Cells

International Journal of Molecular Sciences(2023)10.3390/ijms241813972

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17 citations

Yen-Ching Li, Megumi Murakami, Sung-Han Hsiao, Yun-Chieh Lee, Yang-Hui Huang +5 more

Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105594

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13 citations

Laurent Duvivier, Marie Fourrez, Paula Salazar, Lindsay Sprimont, Di Xia +4 more

Interaction of a Homologous Series of Amphiphiles with P-glycoprotein in a Membrane Environment—Contributions of Polar and Non-Polar Interactions

Pharmaceutics(2023)10.3390/pharmaceutics15010174

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11 citations

Hugo A. L. Filipe, Susana P. Cunha, Cristiana V. Ramos, Patrícia A. T. Martins, Biebele Abel +3 more

ABCB1 and ABCG2 Overexpression Mediates Resistance to the Phosphatidylinositol 3-Kinase Inhibitor HS-173 in Cancer Cell Lines

Cells(2023)10.3390/cells12071056

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11 citations

Cheng‐Yu Hung, Ya‐Ju Hsieh, Megumi Murakami, Yang-Hui Huang, Tsung-Yao Su +5 more

Design, Synthesis and Biological Evaluation of Quinazolinamine Derivatives as Breast Cancer Resistance Protein and P-Glycoprotein Inhibitors with Improved Metabolic Stability

Biomolecules(2023)10.3390/biom13020253

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9 citations

Qiu‐Xu Teng, Megumi Murakami, Suresh V. Ambudkar, Zhe‐Sheng Chen, Vijaya L. Korlipara +1 more

Epidermal Growth Factor Receptor Inhibitor Mobocertinib Resensitizes Multidrug-Resistant Cancer Cells by Attenuating the Human ATP-Binding Cassette Subfamily B Member 1 and Subfamily G Member 2

ACS Pharmacology & Translational Science(2023)10.1021/acsptsci.3c00217

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7 citations

Sung-Han Hsiao, Megumi Murakami, Yang-Hui Huang, Yu‐Tzu Chang, Tai‐Ho Hung +4 more

Residues from Homologous Transmembrane Helices 4 and 10 Are Critical for P-Glycoprotein (ABCB1)-Mediated Drug Transport

Cancers(2023)10.3390/cancers15133459

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8 citations

Mark J. Ware, Andaleeb Sajid, Sabrina Lusvarghi, Stewart R. Durell, Suresh V. Ambudkar +1 more

Second-site suppressor mutations reveal connection between the drug-binding pocket and nucleotide-binding domain 1 of human P-glycoprotein (ABCB1)

Drug Resistance Updates(2023)10.1016/j.drup.2023.101009

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8 citations

Andaleeb Sajid, Sabrina Lusvarghi, Stewart R. Durell, Biebele Abel, Shahrooz Vahedi +3 more

Imperatorin Restores Chemosensitivity of Multidrug-Resistant Cancer Cells by Antagonizing ABCG2-Mediated Drug Transport

Pharmaceuticals(2023)10.3390/ph16111595

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3 citations

Megumi Murakami, Yen-Ching Li, Yang-Hui Huang, Yu‐Tzu Chang, Tai‐Ho Hung +3 more

The Multidrug Resistance Transporter P-glycoprotein Confers Resistance to Ferroptosis Inducers

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.02.23.529736

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2 citations

Lyn M. Huff, José M. González Dalmasy, Paula Salazar, Rachel M. Carter, Ryan T. Gensler +5 more

Data from Apatinib (YN968D1) Reverses Multidrug Resistance by Inhibiting the Efflux Function of Multiple ATP-Binding Cassette Transporters

(2023)10.1158/0008-5472.c.6500690

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0 citations

Yong-ju Liang, Hongbing Huang, Hongyun Zhao, Chung‐Pu Wu, Fang Wang +10 more

Data from Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

(2023)10.1158/0008-5472.c.6497069

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0 citations

Amit K. Tiwari, Chung‐Pu Wu, Xiao‐Dong Su, Si‐Rong Wang, Donggeng Liu +10 more

Data from The Skin Cancer Chemotherapeutic Agent Ingenol-3-Angelate (PEP005) Is a Substrate for the Epidermal Multidrug Transporter (ABCB1) and Targets Tumor Vasculature

(2023)10.1158/0008-5472.c.6500367

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Suneet Shukla, Andrew Lee, Susan H. Garfield, David J. Maloney, Suresh V. Ambudkar +2 more

Data from Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database

(2023)10.1158/1535-7163.c.6531693.v1

Top 100%

0DataRank

Top 100%0 citations

Anna Maria Calcagno, Chung‐Pu Wu, Sudhir Varma, Joanna H. Shih, Min Lin +7 more

Data from Evaluation of current methods used to analyze the expression profiles of ATP-binding cassette transporters yields an improved drug-discovery database

(2023)10.1158/1535-7163.c.6531693

Top 100%

0DataRank

Top 100%0 citations

Anna Maria Calcagno, Chung‐Pu Wu, Sudhir Varma, Joanna H. Shih, Min Lin +7 more

Photodynamic priming modulates cellular ATP levels to overcome P‐glycoprotein‐mediated drug efflux in chemoresistant triple‐negative breast cancer

Photochemistry and Photobiology(2024)10.1111/php.13970

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9 citations

Barry J. Liang, Andaleeb Sajid, Suresh V. Ambudkar, Huang‐Chiao Huang, Idrisa Rahman

Magnolol derivatives as specific and noncytotoxic inhibitors of breast cancer resistance protein (BCRP/ABCG2)

Bioorganic Chemistry(2024)10.1016/j.bioorg.2024.107283

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7 citations

Diogo Henrique Kita, Gustavo Scheiffer, Kelly Karoline dos Santos, Júlia de Paula Dutra, Matteo Augusto Pastore +10 more

Epertinib counteracts multidrug resistance in cancer cells by antagonizing the drug efflux function of ABCB1 and ABCG2

Biomedicine & Pharmacotherapy(2024)10.1016/j.biopha.2024.117542

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6 citations

Yen-Ching Li, Megumi Murakami, Yu‐Shan Wu, Yang-Hui Huang, Tai‐Ho Hung +3 more

Vodobatinib overcomes cancer multidrug resistance by attenuating the drug efflux function of ABCB1 and ABCG2

European Journal of Pharmacology(2024)10.1016/j.ejphar.2024.177231

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3 citations

Bing-Huan Lin, Megumi Murakami, Yu‐Shan Wu, Tai‐Ho Hung, Suresh V. Ambudkar +2 more

Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood–brain barrier

Fluids and Barriers of the CNS(2024)10.1186/s12987-024-00529-5

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8 citations

William J.E. Frye, Robert W. Robey, Andrew Warner, Donna Butcher, Jennifer Matta +6 more

Mutational analysis reveals the importance of residues of the access tunnel inhibitor site to human P‐glycoprotein (ABCB1)‐mediated transport

Protein Science(2024)10.1002/pro.5155

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6 citations

Megumi Murakami, Nandhini Ranganathan, Stewart R. Durell, Suresh V. Ambudkar, Paula Salazar

The colony-stimulating factor-1 receptor inhibitor edicotinib counteracts multidrug resistance in cancer cells by inhibiting ABCG2-mediated drug efflux

Biomedicine & Pharmacotherapy(2024)10.1016/j.biopha.2024.117554

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2 citations

Yun-Chieh Lee, Megumi Murakami, Yang-Hui Huang, Tai‐Ho Hung, Yu‐Shan Wu +3 more

ABCG2 Mediates Resistance to the Dual EGFR and PI3K Inhibitor MTX-211 in Cancer Cells

International Journal of Molecular Sciences(2024)10.3390/ijms25105160

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1 citations

Cheng‐Yu Hung, Megumi Murakami, Yu‐Shan Wu, Yi-Hsuan Chu, Yang-Hui Huang +3 more

Nanoengineered photosensitizers for photodynamic priming to overcome P‐glycoprotein‐mediated multidrug resistance

Photochemistry and Photobiology(2025)10.1111/php.70049

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1 citations

Anju Meda, Kaitlyn A. Moore, Payal Srivastava, Anika Dasgupta, Andaleeb Sajid +3 more

Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors

Bioorganic Chemistry(2025)10.1016/j.bioorg.2025.108941

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1 citations

Ugochi A. Adiele, Griffin Coate, Morgan E. Diolaiti, Huadong Chen, Junhao Lu +11 more

Conversion of Human Multidrug Transporter P-glycoprotein (ABCB1) from Drug Efflux to Uptake Pump: Evidence for a Switch Region Modulating the Direction of Substrate Transport

Journal of Molecular Biology(2025)10.1016/j.jmb.2025.168979

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1 citations

Nandhini Ranganathan, Rajan Guha, Megumi Murakami, Shafaq Ahmed, Stewart R. Durell +2 more

The fourth-generation EGFR tyrosine kinase inhibitor BLU-945 resensitizes ABCG2-overexpressing multidrug-resistant non-small cell lung cancer cells to cytotoxic anticancer drugs

European Journal of Pharmaceutical Sciences(2025)10.1016/j.ejps.2025.107337

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0 citations

Bing-Huan Lin, Megumi Murakami, Yu‐Shan Wu, Tai‐Ho Hung, Suresh V. Ambudkar +2 more

Tetrahydroquinoline/4,5-dihydroisoxazoline derivatives counteract multidrug resistance in cancer cells by inhibiting P-glycoprotein (ABCB1)-mediated transport

Biochimica et Biophysica Acta (BBA) - General Subjects(2025)10.1016/j.bbagen.2025.130894

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0 citations

Diogo Henrique Kita, Azam Rashidian, Luis C. Vesga, Bruna Estelita Ruginsk, Arnold R. Romero Bohórquez +11 more

Suresh V. Ambudkar

Indexed papers

Top data-sharing exemplar

Papers