Irina F. Sevrioukova

Pharmacology, Toxicology and PharmaceuticsMedicineChemistryComputer Science

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 17 papers. Top paper: “Interaction of cytochrome P450 3A4 with cannabinoids and the drug darifenacin”.

Interaction of cytochrome P450 3A4 with cannabinoids and the drug darifenacin

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110709

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0.175DataRank · unranked

2 citations

Irina F. Sevrioukova

Rational Design of CYP3A4 Inhibitors: A One-Atom Linker Elongation in Ritonavir-Like Compounds Leads to a Marked Improvement in the Binding Strength

International Journal of Molecular Sciences(2021)10.3390/ijms22020852

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0DataRank · unranked

21 citations

Irina F. Sevrioukova, Eric R. Samuels

Structural Dynamics of Cytochrome P450 3A4 in the Presence of Substrates and Cytochrome P450 Reductase

Biochemistry(2021)10.1021/acs.biochem.1c00178

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0DataRank · unranked

15 citations

Irina F. Sevrioukova, Christopher J. Thibodeaux, Karine Auclair, Julie Ducharme

Structural Basis for the Diminished Ligand Binding and Catalytic Ability of Human Fetal-Specific CYP3A7

International Journal of Molecular Sciences(2021)10.3390/ijms22115831

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0DataRank · unranked

12 citations

Irina F. Sevrioukova

Structural dynamics of cytochrome P450 3A4 in the presence of substrates and cytochrome P450 reductase

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.09.434557

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0DataRank · unranked

0 citations

Irina F. Sevrioukova, Christopher J. Thibodeaux, Karine Auclair, Julie Ducharme

Interaction of CYP3A4 with Rationally Designed Ritonavir Analogues: Impact of Steric Constraints Imposed on the Heme-Ligating Group and the End-Pyridine Attachment

International Journal of Molecular Sciences(2022)10.3390/ijms23137291

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0DataRank · unranked

7 citations

Irina F. Sevrioukova, Eric R. Samuels

Crystal Structure of CYP3A4 Complexed with Fluorol Identifies the Substrate Access Channel as a High-Affinity Ligand Binding Site

International Journal of Molecular Sciences(2022)10.3390/ijms232012591

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0DataRank · unranked

10 citations

Irina F. Sevrioukova

Ir(III)-Based Agents for Monitoring the Cytochrome P450 3A4 Active Site Occupancy

Inorganic Chemistry(2022)10.1021/acs.inorgchem.2c02587

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0DataRank · unranked

5 citations

Sean J. Steinke, Aliza Majeed, Claudia Turró, Thomas A. Kocarek, Irina F. Sevrioukova +2 more

Interaction of CYP3A4 with caffeine: First insights into multiple substrate binding

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105117

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0DataRank · unranked

20 citations

Irina F. Sevrioukova

Dynamic Ir(III) Photosensors for the Major Human Drug-Metabolizing Enzyme Cytochrome P450 3A4

Inorganic Chemistry(2023)10.1021/acs.inorgchem.3c00059

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0DataRank · unranked

7 citations

Justin J. Ahrens, Marilyn N. Dunbar, Habon Warmahaye, Aliza Majeed, Claudia Turró +4 more

Investigating a new C2-symmetric testosterone dimer and its dihydrotestosterone analog: Synthesis, antiproliferative activity on prostate cancer cell lines and interaction with CYP3A4

European Journal of Medicinal Chemistry(2023)10.1016/j.ejmech.2023.115222

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0DataRank · unranked

3 citations

Laurie Fortin, Julie Girouard, Carlos Reyes‐Moreno, Irina F. Sevrioukova, Gervais Bérubé +1 more

Mixed Ru(II)–Ir(III) Complexes as Photoactive Inhibitors of the Major Human Drug Metabolizing Enzyme CYP3A4

Inorganic Chemistry(2024)10.1021/acs.inorgchem.4c02633

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0DataRank · unranked

6 citations

Madeline Denison, Santana P. Garcia, Sayak Gupta, Thomas A. Kocarek, Irina F. Sevrioukova +3 more

Interaction of CYP3A4 with the inhibitor cobicistat: Structural and mechanistic insights and comparison with ritonavir

Archives of Biochemistry and Biophysics(2024)10.1016/j.abb.2024.110071

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0DataRank · unranked

5 citations

Irina F. Sevrioukova

Synthesis and anticancer properties of a hybrid molecule with the testosterone and estradiol head-groups

Steroids(2024)10.1016/j.steroids.2024.109469

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0DataRank · unranked

3 citations

Fayanne Nolin, Chahrazed Bouzriba, Sébastien Fortin, Irina F. Sevrioukova, Gervais Bérubé +1 more

Evaluation of Larger Side‐Group Functionalities and the Side/End‐Group Interplay in Ritonavir‐Like Inhibitors of CYP3A4

Chemical Biology & Drug Design(2025)10.1111/cbdd.70043

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0DataRank · unranked

1 citations

Irina F. Sevrioukova, Eric R. Samuels

An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4

Bioorganic & Medicinal Chemistry(2020)10.1016/j.bmc.2020.115349

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0DataRank · unranked

18 citations

Irina F. Sevrioukova, Eric R. Samuels

Interaction of cytochrome P450 3A4 with the hydrophilic ligand tetraethylene glycol

Biochemical and Biophysical Research Communications(2025)10.1016/j.bbrc.2025.153040

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0DataRank · unranked

0 citations

Irina F. Sevrioukova