J. Silvio Gutkind

Biochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

1in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 1 indexed paper attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Data from A Randomized Multi-institutional Phase II Trial of Everolimus as Adjuvant Therapy in Patients with Locally Advanced Squamous Cell Cancer of the Head and Neck

(2023)10.1158/1078-0432.c.6532910.v1

Top 100%

0DataRank

Top 100%0 citations

D. Neil Hayes, Theodore Karrison, Olivier Harismendy, José M. Flores, Tara Moore‐Medlin +17 more

Papers

Driven by 74 papers — median percentile 0. Top paper: “HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers”.

HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers

Oncogene(2020)10.1038/s41388-020-01431-8

N/A

2.5DataRank · unranked

100 citations

Daria A. Gaykalova, Theresa Guo, Alexander V. Favorov, Elana J. Fertig, Pablo Tamayo +18 more

Interpretation of cancer mutations using a multiscale map of protein systems

Science(2021)10.1126/science.abf3067

N/A

2.1DataRank · unranked

88 citations

Marcus R. Kelly, Dana J. Ramms, Marissa L. Heintschel, Kai Tao, Beril Tutuncuoglu +27 more

The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure

Nature Immunology(2023)10.1038/s41590-023-01529-7

N/A

1.9DataRank · unranked

88 citations

Bryan S. Yung, Farhoud Faraji, Robert Saddawi‐Konefka, Zhiyong Wang, Alexander T. Wenzel +16 more

Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer

Nature Communications(2024)10.1038/s41467-024-47423-0

N/A

1.7DataRank · unranked

93 citations

Yu‐Ting Chou, Lauren Čech, Celia Fernández-Méndez, Johnny Yu, Victor Olivas +30 more

Gαs–Protein Kinase A (PKA) Pathway Signalopathies: The Emerging Genetic Landscape and Therapeutic Potential of Human Diseases Driven by Aberrant Gαs-PKA Signaling

Pharmacological Reviews(2021)10.1124/pharmrev.120.000269

N/A

1.6DataRank · unranked

74 citations

Francesco Raimondi, Nadia Arang, Friedrich W. Herberg, Susan S. Taylor, J. Silvio Gutkind +1 more

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer

Nature Communications(2022)10.1038/s41467-022-28691-0

N/A

0.745DataRank · unranked

143 citations

Tracy Tang, Gary D. Probst, Andrei W. Konradi, Chunyu Jin, Fulong Li +4 more

Tipifarnib as a Precision Therapy for HRAS -Mutant Head and Neck Squamous Cell Carcinomas

Molecular Cancer Therapeutics(2020)10.1158/1535-7163.mct-19-0958

N/A

0.713DataRank · unranked

115 citations

Zhiyong Wang, Marco Proietto, Anastasia Chillà, Juan Luis Calleja-Valera, Yusuke Goto +9 more

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

Nature Communications(2023)10.1038/s41467-023-38271-5

N/A

0.633DataRank · unranked

67 citations

Timothy J. Sears, Victoria H. Wu, Eva Pérez‐Guijarro, Hyo Kim, A. Castro +24 more

Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy

Nature Communications(2022)10.1038/s41467-022-31601-z

N/A

0.633DataRank · unranked

67 citations

Michael M. Allevato, Maria F. Camargo, Jacqueline Lesperance, Maryam A. Quraishi, Joseph Aguilera +12 more

A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors

Nature Cancer(2023)10.1038/s43018-022-00508-5

N/A

0.574DataRank · unranked

45 citations

Chloé E. Atreya, Changjun Wang, Bo Pan, Courtney A. Dreyer, Diede Brunen +20 more

Somatic 9p24.1 alterations in HPV – head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2213835119

N/A

0.571DataRank · unranked

44 citations

Ezra E.W. Cohen, William N. William, Joy J. Bianchi, Jim Abraham, Daniel Magee +7 more

Pathway-Specific Genome Editing of PI3K/mTOR Tumor Suppressor Genes Reveals that PTEN Loss Contributes to Cetuximab Resistance in Head and Neck Cancer

Molecular Cancer Therapeutics(2020)10.1158/1535-7163.mct-19-1036

N/A

0.515DataRank · unranked

30 citations

Zhiyong Wang, Yusuke Goto, Toshinori Ando, Xingyu Wu, Xuefeng Zhang +5 more

Aberrant expression of CPSF1 promotes head and neck squamous cell carcinoma via regulating alternative splicing

PLoS ONE(2020)10.1371/journal.pone.0233380

N/A

0.483DataRank · unranked

24 citations

Mizuo Ando, Takahito Fukusumi, Shuling Ren, Chao Liu, Jesse R. Qualliotine +12 more

Catalytic site mutations confer multiple states of G protein activation

Science Signaling(2023)10.1126/scisignal.abq7842

N/A

0.470DataRank · unranked

22 citations

Ning Ma, Nadia Arang, Sarah A. Martin, Ajit Prakash, Jeffrey F. DiBerto +9 more

YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution

Nature Communications(2025)10.1038/s41467-024-55660-6

N/A

0.449DataRank · unranked

19 citations

Sydney I. Ramirez, Lauren Clubb, Kuniaki Sato, Valeria Burghi, Thomas S. Hoang +18 more

A focal adhesion kinase-YAP signaling axis drives drug tolerant persister cells and residual disease in lung cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.10.23.465573

N/A

0.442DataRank · unranked

18 citations

Celia Fernández-Méndez, Lauren Čech, Johnny Yu, Ismail M. Meraz, Victor Olivas +28 more

Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ–focal adhesion kinase signaling circuitry

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102866

N/A

0.434DataRank · unranked

17 citations

Simone Lubrano, Damiano Cosimo Rigiracciolo, Daniela Nachmanson, Scott M. Lippman, Prashant Mali +3 more

Gα12 signaling regulates transcriptional and phenotypic responses that promote glioblastoma tumor invasion

Scientific Reports(2023)10.1038/s41598-023-49164-4

N/A

0.330DataRank · unranked

8 citations

Shunichiro Miki, Briana C. Prager, Jianhui Ma, Anthony Y. Jeong, Jacqueline Lara +8 more

The landscape of cancer rewired GPCR signaling axes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.03.13.532291

N/A

0.292DataRank · unranked

6 citations

Marin Matic, Pierluigi DiChiaro, Natalia De Oliveira Rosa, Francesco Carli, Lauren Clubb +10 more

Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation

npj Systems Biology and Applications(2024)10.1038/s41540-024-00400-1

N/A

0.241DataRank · unranked

4 citations

Kodye L. Abbott, Nadia Arang, Kathryn Lande, Navneet Kaur, Melinda Tong +4 more

YAP-Driven Malignant Reprogramming of Epithelial Stem Cells at Single Cell Resolution

Research Square(2023)10.21203/rs.3.rs-3426301/v1

N/A

0.241DataRank · unranked

4 citations

Farhoud Faraji, Sydney I. Ramirez, Lauren Clubb, Kuniaki Sato, Paola Anguiano Quiroz +15 more

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science(2025)10.1002/advs.202506552

N/A

0.241DataRank · unranked

4 citations

Bryan S. Yung, Michael M. Allevato, Ming Cheng, Maria F. Camargo, Robert Saddawi‐Konefka +13 more

A Network Landscape of HPVOPC Reveals Methylation Alterations as Significant Drivers of Gene Expression via an Immune-Mediated GPCR Signal

Cancers(2023)10.3390/cancers15174379

N/A

0.208DataRank · unranked

3 citations

Takuya Nakagawa, Sara Brin Rosenthal, Sayed Sadat, Carmen Ballesteros‐Merino, Guorong Xu +10 more

Linoleoyl-lysophosphatidylcholine suppresses immune-related adverse events due to immune checkpoint blockade

medRxiv(2024)10.1101/2024.08.07.24310974

N/A

0.208DataRank · unranked

3 citations

Priyanka Saminathan, Mir Henglin, Mingyue Liu, Namratha Nadig, Camille Fang +28 more

Unraveling Resistance Mechanisms to Gαq Pathway Inhibition in Uveal Melanoma: Insights from Signaling-Activation Library Screening

Cancers(2025)10.3390/cancers18010074

N/A

0.104DataRank · unranked

1 citations

Rodolfo Daniel Cervantes‐Villagrana, Nadia Arang, Elena Sofia Cardenas-Alcoser, Kuniaki Sato, Gabriela Cuesta-Margolles +4 more

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.14.436660

N/A

0.104DataRank · unranked

1 citations

Victoria H. Wu, Eva Pérez‐Guijarro, Hyo Kim, Andrea Castro, James V. Talwar +20 more

Data from Snail Up-regulates Proinflammatory Mediators and Inhibits Differentiation in Oral Keratinocytes

(2023)10.1158/0008-5472.c.6518092

N/A

0DataRank · unranked

0 citations

Vyomesh Patel, Naomi C. Roue, Sandra Fok, Lilian Soon, Gary M. Halliday +2 more

Data from Snail Up-regulates Proinflammatory Mediators and Inhibits Differentiation in Oral Keratinocytes

(2023)10.1158/0008-5472.c.6518092.v1

N/A

0DataRank · unranked

0 citations

Vyomesh Patel, Naomi C. Roue, Sandra Fok, Lilian Soon, Gary M. Halliday +2 more

Data from A Randomized Multi-institutional Phase II Trial of Everolimus as Adjuvant Therapy in Patients with Locally Advanced Squamous Cell Cancer of the Head and Neck

(2023)10.1158/1078-0432.c.6532910.v1

Top 100%

0DataRank

Top 100%0 citations

D. Neil Hayes, Theodore Karrison, Olivier Harismendy, José M. Flores, Tara Moore‐Medlin +17 more

Data from Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ-Driven Uveal Melanoma

(2023)10.1158/1078-0432.c.6529851

N/A

0DataRank · unranked

0 citations

Monica Acosta, Robert Saddawi‐Konefka, Ayush Kishore, Simone Lubrano, Frederico Gomes +13 more

Structural and dynamic changes in P-Rex1 upon activation by PIP 3 and inhibition by IP 4

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.09.15.557836

N/A

0DataRank · unranked

0 citations

Sendi Rafael Adame-Garcia, Sheng Li, Chun-Liang Chen, Michael A. Cianfrocco, J. Silvio Gutkind +3 more

Reviewer #1 (Public Review): Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

(2023)10.7554/elife.92822.1.sa2

N/A

0DataRank · unranked

0 citations

Rafael Adame-Garcia, Sheng Li, Chun-Liang Chen, Michael A. Cianfrocco, J. Silvio Gutkind +3 more

Reviewer #2 (Public Review): Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

(2023)10.7554/elife.92822.1.sa1

N/A

0DataRank · unranked

0 citations

Sendi Rafael Adame-Garcia, Sheng Li, Chun-Liang Chen, Michael A. Cianfrocco, J. Silvio Gutkind +3 more

Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

(2023)10.7554/elife.92822.1

N/A

0DataRank · unranked

0 citations

Sendi Rafael Adame-Garcia, Sheng Li, Chun-Liang Chen, Michael A. Cianfrocco, J. Silvio Gutkind +3 more

Let it be: Preserving tumor-draining lymph nodes in the era of immuno-oncology

Cancer Cell(2024)10.1016/j.ccell.2024.05.015

N/A

0DataRank · unranked

36 citations

Shiruyeh Schokrpur, J. Silvio Gutkind, Robert Saddawi‐Konefka

The landscape of cancer-rewired GPCR signaling axes

Cell Genomics(2024)10.1016/j.xgen.2024.100557

N/A

0DataRank · unranked

24 citations

Marin Matic, Luisa Bisceglia, Pierluigi Di Chiaro, Natalia De Oliveira Rosa, Francesco Carli +11 more

The XCL1–XCR1 axis supports intestinal tissue residency and antitumor immunity

The Journal of Experimental Medicine(2024)10.1084/jem.20240776

N/A

0DataRank · unranked

15 citations

K Mempel, Alexander Monell, Miguel Reina‐Campos, Nicole E. Scharping, Maximilian Heeg +7 more

Tumor-Targeted Cell-Penetrating Peptides Reveal That Monomethyl Auristatin E Temporally Modulates the Tumor Immune Microenvironment

Molecules(2024)10.3390/molecules29235618

N/A

0DataRank · unranked

8 citations

Ming Cheng, Alina Ali, Jacqueline Lesperance, Dina V. Hingorani, Mike M. Allevato +7 more

Oncogenic HRAS Induces Metformin Resistance in Head and Neck Cancer by Promoting Glycolytic Metabolism

Cancer Prevention Research(2024)10.1158/1940-6207.capr-24-0124

N/A

0DataRank · unranked

3 citations

Sendi Rafael Adame-Garcia, Keiichi Koshizuka, Pham Thuy Tien Vo, Thomas S. Hoang, Kuniaki Sato +7 more

Reviewer #2 (Public Review): Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

(2024)10.7554/elife.92822.2.sa1

N/A

0DataRank · unranked

0 citations

Sendi Rafael Adame-Garcia, Sheng Li, Chun-Liang Chen, Michael A. Cianfrocco, J. Silvio Gutkind +3 more

Author response: Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

(2024)10.7554/elife.92822.3.sa4

N/A

0DataRank · unranked

0 citations

Sendi Rafael Adame-Garcia, Sheng Li, Chun-Liang Chen, Michael A. Cianfrocco, J. Silvio Gutkind +3 more

FAK inhibition combined with the RAF-MEK clamp avutometinib overcomes resistance to targeted and immune therapies in BRAF V600E melanoma

Cancer Cell(2025)10.1016/j.ccell.2025.02.001

N/A

0DataRank · unranked

38 citations

Rodolfo Daniel Cervantes‐Villagrana, Farhoud Faraji, Sydney I. Ramirez, Kuniaki Sato, Sendi Rafael Adame-Garcia +15 more

Targeting YAP/TAZ-TEAD signaling as a therapeutic approach in head and neck squamous cell carcinoma

Cancer Letters(2025)10.1016/j.canlet.2025.217467

N/A

0DataRank · unranked

23 citations

Farhoud Faraji, Rodolfo Daniel Cervantes‐Villagrana, Xingyu Wu, Keiichi Koshizuka, Tomohiko Ishikawa +7 more

Genome-Wide CRISPR Screening Reveals That mTOR Inhibition Initiates Ferritinophagy and Ferroptosis in Head and Neck Cancer

Cancer Research(2025)10.1158/0008-5472.can-24-3785

N/A

0DataRank · unranked

8 citations

Xingyu Wu, Kuniaki Sato, Pham Thuy Tien Vo, Gosia M. Murawska, Tomohiko Ishikawa +7 more

Multistate oral carcinogenesis—A prospective cohort study and a parallel case-control study in Taiwan

Oral Oncology(2025)10.1016/j.oraloncology.2025.107210

N/A

0DataRank · unranked

5 citations

Kelly J. Yu, Tseng‐Cheng Chen, Ming-shui Tsai, Chung-Jan Kang, Chih‐Yen Chien +21 more

Chemokine-chemokine receptor networks in conventional type I dendritic cells: an opportunity to prime and boost anticancer immunity

Journal of Pharmacology and Experimental Therapeutics(2025)10.1016/j.jpet.2025.103725

N/A

0DataRank · unranked

1 citations

Charlotte Shinn, Shiruyeh Schokrpur, Juliana Idoyaga, Tracy M. Handel, J. Silvio Gutkind +1 more

Inhibition of anti-apoptotic BCL2 overcomes adaptive resistance to co-targeting of the protein kinase FAK and MEK in GNAQ-driven uveal melanoma

Journal of Biological Chemistry(2025)10.1016/j.jbc.2025.110712

N/A

0DataRank · unranked

1 citations

Rodolfo Daniel Cervantes‐Villagrana, Nadia Arang, Adam Officer, Sendi Rafael Adame-Garcia, Gabriela Cuesta-Margolles +3 more

Activating the CXCR3/CXCL10 pathway overrides tumor immune suppression by enhancing immune trafficking and effector cell priming in head and neck squamous cell carcinoma

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.04.24.650529

N/A

0DataRank · unranked

7 citations

Robert Saddawi‐Konefka, Catherina L. Salanga, Shiruyeh Schokrpur, J. Silvio Gutkind, Tracy M. Handel +1 more

871 Immune architecture by design: chemokines as tools to sculpt the immune composition of solid tumors

Regular and Young Investigator Award Abstracts(2025)10.1136/jitc-2025-sitc2025.0871

N/A

0DataRank · unranked

0 citations

Robert Saddawi‐Konefka, Shiruyeh Schokrpur, Catherina L. Salanga, J. Silvio Gutkind, Tracy M. Handel +1 more

G protein-regulated endocytic trafficking of adenylyl cyclase type 9

eLife(2020)10.7554/elife.58039

N/A

0DataRank · unranked

61 citations

Roshanak Irannejad, Tanya A. Baldwin, Aparna Sundaram, J. Silvio Gutkind, Asuka Inoue +3 more

Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK–YAP signaling axis

Oncogene(2020)10.1038/s41388-020-1272-x

N/A

0DataRank · unranked

42 citations

Toshinori Ando, Hiroki Izumi, Xiaodong Feng, Nadia Arang, Mara Gilardi +4 more

Anti-angiogenic effects of VEGF stimulation on endothelium deficient in phosphoinositide recycling

Nature Communications(2020)10.1038/s41467-020-14956-z

N/A

0DataRank · unranked

29 citations

Olivia Farrelly, Constantinos M. Mikelis, Mayumi F. Miller, Zhiyong Wang, Van N. Pham +10 more

Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors

Biomaterials(2020)10.1016/j.biomaterials.2020.120032

N/A

0DataRank · unranked

23 citations

Jessica L. Crisp, Matthew K. Doan, Maria F. Camargo, Maryam A. Quraishi, Joseph Aguilera +10 more

Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

Nature Communications(2021)10.1038/s41467-021-22619-w

N/A

0DataRank · unranked

86 citations

Yusuke Goto, Michael M. Allevato, Victoria H. Wu, Robert Saddawi‐Konefka, Mara Gilardi +10 more

Synthetic Lethal Screens Reveal Cotargeting FAK and MEK as a Multimodal Precision Therapy for GNAQ -Driven Uveal Melanoma

Clinical Cancer Research(2021)10.1158/1078-0432.ccr-20-3363

N/A

0DataRank · unranked

77 citations

Monica Acosta, Robert Saddawi‐Konefka, Ayush Kishore, Simone Lubrano, Frederico Gomes +13 more

EGFR Regulates the Hippo pathway by promoting the tyrosine phosphorylation of MOB1

Communications Biology(2021)10.1038/s42003-021-02744-4

N/A

0DataRank · unranked

63 citations

Nadia Arang, Zhiyong Wang, Daniela Elena Costea, Xiaodong Feng, Yusuke Goto +5 more

Cancer-associated fibroblast secretion of PDGFC promotes gastrointestinal stromal tumor growth and metastasis

Oncogene(2021)10.1038/s41388-021-01685-w

N/A

0DataRank · unranked

55 citations

Chih-Min Tang, Sudeep Banerjee, Mayra Yebra, Sangkyu Noh, Adam M. Burgoyne +17 more

Microneedle-mediated intratumoral delivery of anti-CTLA-4 promotes cDC1-dependent eradication of oral squamous cell carcinoma with limited irAEs

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.07.471658

N/A

0DataRank · unranked

3 citations

Robert Saddawi‐Konefka, Victoria H. Wu, Miguel Angel Lopez‐Ramirez, Zhiyong Wang, Fernando Soto +11 more

Pan-cancer analysis of patient tumor single-cell transcriptomes identifies promising selective and safe CAR targets in head and neck cancer

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.09.29.462485

N/A

0DataRank · unranked

1 citations

Sanju Sinha, J. Silvio Gutkind, Ezra E.W. Cohen, Alejandro A. Schäffer, Eytan Ruppin +1 more

Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC

Nature Communications(2022)10.1038/s41467-022-31941-w

N/A

0DataRank · unranked

176 citations

Aoife O’Farrell, Farhoud Faraji, Lauren Clubb, Michael M. Allevato, Shawn M. Jensen +17 more

Microneedle-mediated Intratumoral Delivery of Anti-CTLA-4 Promotes cDC1-dependent Eradication of Oral Squamous Cell Carcinoma with Limited irAEs

Molecular Cancer Therapeutics(2022)10.1158/1535-7163.mct-21-0234

N/A

0DataRank · unranked

46 citations

Robert Saddawi‐Konefka, Victoria H. Wu, Miguel Angel Lopez‐Ramirez, Zhiyong Wang, Fernando Soto +11 more

Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer

Cells(2022)10.3390/cells11081370

N/A

0DataRank · unranked

39 citations

Sydney I. Ramirez, Paola Y. Anguiano Quiroz, Amaya N. Mendez-Molina, J. Silvio Gutkind, Farhoud Faraji

Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1

Journal of Biological Chemistry(2022)10.1016/j.jbc.2022.102209

N/A

0DataRank · unranked

7 citations

Chun-Liang Chen, Sandeep K. Ravala, Jennifer N. Cash, Larisa Avramova, Mariya V. Zhalnina +4 more

Lymphatic-Preserving Treatment Sequencing with Immune Checkpoint Inhibition Unleashes cDC1-Dependent Antitumor Immunity in HNSCC

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.01.478744

N/A

0DataRank · unranked

9 citations

Aoife O’Farrell, Farhoud Faraji, Lauren Clubb, Michael M. Allevato, Nana-Ama A.S. Anang +16 more

A reversible SRC-relayed COX2-inflammatory program drives therapeutic resistance in BRAF V600E colorectal tumors

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.10.20.512885

N/A

0DataRank · unranked

0 citations

Chloé E. Atreya, Changjun Wang, Bo Pan, Courtney A. Dreyer, Diede Brunen +20 more

High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma

Cell Reports Medicine(2023)10.1016/j.xcrm.2023.101244

N/A

0DataRank · unranked

25 citations

Simone Lubrano, Michele Ceribelli, Damiano Cosimo Rigiracciolo, Robert Saddawi‐Konefka, Farhoud Faraji +18 more

Mutated HRAS Activates YAP1–AXL Signaling to Drive Metastasis of Head and Neck Cancer

Cancer Research(2023)10.1158/0008-5472.can-22-2586

N/A

0DataRank · unranked

24 citations

Manu Prasad, Mai Badarni, Talal Ben Lulu, Vijayasteltar Belsamma Liju, Sooraj Mathukkada +20 more

Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105293

N/A

0DataRank · unranked

15 citations

Justine S. Paradis, Adam Officer, Sendi Rafael Adame-Garcia, Xingyu Wu, Edda S. F. Matthees +11 more

Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma

Journal of Biological Chemistry(2023)10.1016/j.jbc.2023.105418

N/A

0DataRank · unranked

7 citations

Alison Kurimchak, Isabella V. Trachtenberg, Timothy J. Purwin, Jelan I. Haj, Anna Han +10 more

Pan-Cancer Analysis of Patient Tumor Single-Cell Transcriptomes Identifies Promising Selective and Safe Chimeric Antigen Receptor Targets in Head and Neck Cancer

Cancers(2023)10.3390/cancers15194885

N/A

0DataRank · unranked

6 citations

Sanju Sinha, Tiangen Chang, J. Silvio Gutkind, Ezra E.W. Cohen, Alejandro A. Schäffer +2 more

Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

eLife(2023)10.7554/elife.92822

N/A

0DataRank · unranked

2 citations

Sendi Rafael Adame-Garcia, Sheng Li, Chun-Liang Chen, Michael A. Cianfrocco, J. Silvio Gutkind +3 more

Data from A Retroinhibition Approach Reveals a Tumor Cell–Autonomous Response to Rapamycin in Head and Neck Cancer

(2023)10.1158/0008-5472.c.6497783

N/A

0DataRank · unranked

0 citations

Vyomesh Patel, Kantima Leelahavanichkul, Robert T. Abraham, J. Silvio Gutkind, Panomwat Amornphimoltham

Data from A Retroinhibition Approach Reveals a Tumor Cell–Autonomous Response to Rapamycin in Head and Neck Cancer

(2023)10.1158/0008-5472.c.6497783.v1

N/A

0DataRank · unranked

0 citations

Vyomesh Patel, Kantima Leelahavanichkul, Robert T. Abraham, J. Silvio Gutkind, Panomwat Amornphimoltham

Data from 4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer

(2023)10.1158/0008-5472.c.6511397.v1

N/A

0DataRank · unranked

0 citations

Xiaodong Feng, Alfredo Molinolo, Daniel Martı́n, Lynn Vitale‐Cross, Nijiro Nohata +15 more

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