Darrell J. Irvine

Also affiliated with International AIDS Vaccine Initiative, Howard Hughes Medical Institute, Ragon Institute of MGH, MIT and Harvard, Massachusetts General Hospital, Massachusetts Institute of Technology

Immunology and MicrobiologyBiochemistry, Genetics and Molecular BiologyMedicine

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 100%percentile

0Author DataRank

Indexed papers

0in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Papers

Driven by 111 papers. Top paper: “Low protease activity in B cell follicles promotes retention of intact antigens after immunization”.

Low protease activity in B cell follicles promotes retention of intact antigens after immunization

Science(2023)10.1126/science.abn8934

N/A

2.7DataRank · unranked

97 citations

Ang Cui, Laura Maiorino, Ava P. Amini, Justin R. Gregory, Maurice Bukenya +21 more

ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer

Nature Cancer(2023)10.1038/s43018-023-00591-2

N/A

1.4DataRank · unranked

42 citations

Enrico Patrucco, Cristina Mastini, Navin R. Mahadevan, Tran C. Thai, Elisa Bergaggio +26 more

Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.03.03.433558

N/A

0.778DataRank · unranked

19 citations

Sergio A. Rodriguez‐Aponte, Brittany L. Hartwell, Lisa H. Tostanoski, Andrew M. Biedermann, Laura E. Crowell +35 more

Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines

Science Advances(2025)10.1126/sciadv.adr2631

N/A

0.613DataRank · unranked

27 citations

John H. Klich, Carolyn K. Jons, Tianyang Mao, Namit Chaudhary, Ashley Utz +9 more

Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

Cell(2020)10.1016/j.cell.2019.12.027

N/A

0.612DataRank · unranked

58 citations

Diane G. Carnathan, Bartek Nogal, Jacob T. Martin, Oscar L. Rodriguez, Amit A. Upadhyay +29 more

Long-lasting germinal center responses to a priming immunization with continuous proliferation and somatic mutation

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.12.20.473537

N/A

0.555DataRank · unranked

11 citations

Henry J. Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall +31 more

Neoantigen architectures define immunogenicity and drive immune evasion of tumors with heterogenous neoantigen expression

Journal for ImmunoTherapy of Cancer(2024)10.1136/jitc-2024-010249

N/A

0.483DataRank · unranked

24 citations

Andrea Castro, Yufei Cui, Noora Harake, B.J. Kim, Jonathan Dye +6 more

Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma

Frontiers in Immunology(2022)10.3389/fimmu.2022.886683

N/A

0.416DataRank · unranked

15 citations

Coralie M. Backlund, Duncan M. Morgan, Byong H. Kang, Nishant K. Singh, Brooke D. Huisman +15 more

Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies

Cell Reports(2022)10.1016/j.celrep.2022.110436

N/A

0.387DataRank · unranked

9 citations

Edgar A. Hodge, Celia C. LaBranche, Tiffany M. Styles, Xiaoying Shen, Narayanaiah Cheedarla +10 more

Full-length single-cell BCR sequencing paired with RNA sequencing reveals convergent responses to pneumococcal vaccination

Communications Biology(2024)10.1038/s42003-024-06823-0

N/A

0.376DataRank · unranked

9 citations

Yiming J. Zhang, Jin Hwan Kim, MaryAnn Murillo, Suddham Singh, Jakob Loschko +10 more

Priming antibody responses to the fusion peptide in rhesus macaques

npj Vaccines(2024)10.1038/s41541-024-00918-9

N/A

0.312DataRank · unranked

7 citations

Payal Pratap, Kimberly M. Cirelli, Diane G. Carnathan, Chiamaka A. Enemuo, Aleksandar Antanasijevic +16 more

Visualizing lipid nanoparticle trafficking for mRNA vaccine delivery in non-human primates

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.06.21.600088

N/A

0.292DataRank · unranked

6 citations

Mariluz Araínga, Laura Maiorino, Ivan S. Pires, Beomjoon Kim, Katarzyna Kaczmarek Michaels +9 more

Two-dose “extended priming” immunization amplifies humoral immune responses by synchronizing vaccine delivery with the germinal center response

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.20.563479

N/A

0.269DataRank · unranked

5 citations

Leerang Yang, Laura Maiorino, Elana Ben‐Akiva, Kristen A. Rodrigues, Anna Romanov +7 more

Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons

ACS Central Science(2024)10.1021/acscentsci.3c01544

N/A

0.208DataRank · unranked

3 citations

Somesh Mohapatra, Mariane B. Melo, Jacob Rodriguez, Na Li, Wuhbet Abraham +8 more

Leveraging tissue-resident memory T cells for non-invasive immune monitoring via microneedle skin patches

medRxiv(2025)10.1101/2025.03.17.25324099

N/A

0.104DataRank · unranked

1 citations

Ryan R. Hosn, Wei-Che Ko, Khashayar Afshari, Ashok Kumar Dhinakaran, Namit Chaudhary +10 more

The Injury Response to DNA Damage Promotes Anti-Tumor Immunity

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.26.062216

N/A

0DataRank · unranked

2 citations

Lauren E. Milling, Jung-Kuei Chen, Wuhbet Abraham, Erika D. Handly, Darrell J. Irvine +2 more

Ivermectin converts cold tumors hot and synergies with immune checkpoint blockade for treatment of breast cancer

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.08.21.261511

N/A

0DataRank · unranked

1 citations

Zhen Han, Nitasha R. Bennett, Darrell J. Irvine, Peter P. Lee, Dobrin Draganov

Intratumoral administration of DNA-damaging chemotherapy-treated tumor cells to enhance therapeutic benefit of systemic immune checkpoint blockade in mouse cancer models.

Journal of Clinical Oncology(2020)10.1200/jco.2020.38.5_suppl.77

N/A

0DataRank · unranked

0 citations

Lauren E. Milling, Jung-Kuei Chen, Wuhbet Abraham, Darrell J. Irvine, Michael B Yaffe +1 more

Evolution of Toll-like receptor 7/8 agonist therapeutics and their delivery approaches: From antiviral formulations to vaccine adjuvants

Advanced Drug Delivery Reviews(2021)10.1016/j.addr.2021.05.013

N/A

0DataRank · unranked

186 citations

Jeremiah A. Johnson, Darrell J. Irvine, Sachin Bhagchandani

A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity

Science Immunology(2021)10.1126/sciimmunol.abf1152

N/A

0DataRank · unranked

175 citations

Yu Kato, Mariane B. Melo, Ivy Phung, Brian L. Freeman, Zhong‐Ming Li +36 more

Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2106845118

N/A

0DataRank · unranked

101 citations

Sergio A. Rodriguez‐Aponte, Brittany L. Hartwell, Lisa H. Tostanoski, Andrew M. Biedermann, Laura E. Crowell +39 more

Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

Science Advances(2021)10.1126/sciadv.abh2791

N/A

0DataRank · unranked

66 citations

Raiees Andrabi, Christopher A. Cottrell, Sara T. Richey, Ge Song, Sean Callaghan +12 more

Ivermectin converts cold tumors hot and synergizes with immune checkpoint blockade for treatment of breast cancer

npj Breast Cancer(2021)10.1038/s41523-021-00229-5

N/A

0DataRank · unranked

46 citations

Zhen Han, Aamir Rana, Nitasha R. Bennett, Darrell J. Irvine, Peter P. Lee +1 more

Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates

Biomaterials(2021)10.1016/j.biomaterials.2021.120868

N/A

0DataRank · unranked

40 citations

Brittany L. Hartwell, Sidath C. Kumarapperuma, Mariane B. Melo, Diane G. Carnathan, Benjamin Cossette +14 more

Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2

Science Advances(2021)10.1126/sciadv.abj6538

N/A

0DataRank · unranked

36 citations

Sergio A. Rodriguez‐Aponte, Neil C. Dalvie, Jeong Hyun Lee, Wuhbet Abraham, Diane G. Carnathan +17 more

A participant-derived xenograft model of HIV enables long-term evaluation of autologous immunotherapies

The Journal of Experimental Medicine(2021)10.1084/jem.20201908

N/A

0DataRank · unranked

24 citations

Christiaan H. van Dorp, Ali Danesh, Adam R. Ward, Thomas R. Dilling, Talia M. Mota +14 more

IgG-Engineered Protective Antigen for Cytosolic Delivery of Proteins into Cancer Cells

ACS Central Science(2021)10.1021/acscentsci.0c01670

N/A

0DataRank · unranked

15 citations

Nicholas L. Truex, Mariane B. Melo, Yiran Cheng, Na Li, Darrell J. Irvine +2 more

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.05.451222

N/A

0DataRank · unranked

12 citations

Meng Yuan, Sean Callaghan, Rami Musharrafieh, Ge Song, Murillo Silva +29 more

Disassembly of HIV envelope glycoprotein trimer immunogens is driven by antibodies elicited via immunization

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.02.16.431310

N/A

0DataRank · unranked

10 citations

Raiees Andrabi, Christopher A. Cottrell, Sara T. Richey, Ge Song, Sean Callaghan +12 more

Spatially regulated protease activity in lymph nodes renders B cell follicles a sanctuary for retention of intact antigens

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.11.15.468669

N/A

0DataRank · unranked

5 citations

Ang Cui, Ava P. Soleimany, Maurice Bukenya, Heya Lee, Christopher A. Cottrell +17 more

CARPOOL: A library-based platform to rapidly identify next generation chimeric antigen receptors

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.09.450900

N/A

0DataRank · unranked

4 citations

Khloe S. Gordon, Caleb R. Perez, Patrick V. Holec, Azucena Ramos, Angela Q. Zhang +9 more

Engineering autoreactive T and B cell responses toward active immunotherapy for inflammatory diseases

Proceedings of the National Academy of Sciences(2021)10.1073/pnas.2104743118

N/A

0DataRank · unranked

0 citations

Darrell J. Irvine, Jason Y.H. Chang

Changes at V2 apex of HIV-1 Clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.15.447100

N/A

0DataRank · unranked

0 citations

Edgar A. Hodge, Celia C. LaBranche, Tiffany Turner Styles, Xiaoying Shen, Narayanaiah Cheedarla +10 more

Long-primed germinal centres with enduring affinity maturation and clonal migration

Nature(2022)10.1038/s41586-022-05216-9

N/A

0DataRank · unranked

194 citations

Henry J. Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall +33 more

Optimization of storage conditions for lipid nanoparticle-formulated self-replicating RNA vaccines

Journal of Controlled Release(2022)10.1016/j.jconrel.2022.11.022

N/A

0DataRank · unranked

136 citations

Ryan R. Hosn, Tanaka Remba, Dong Soo Yun, Na Li, Wuhbet Abraham +7 more

An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity

Cell(2022)10.1016/j.cell.2022.01.009

N/A

0DataRank · unranked

124 citations

Valentina Poli, Ellen Shrock, Roberto Spreafico, Xin Liu, Novalia Pishesha +29 more

Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains

Nature Biomedical Engineering(2022)10.1038/s41551-022-00896-0

N/A

0DataRank · unranked

65 citations

Taeyoon Kyung, Caleb R. Perez, Patrick V. Holec, Azucena Ramos, Angela Q. Zhang +10 more

Mannose-binding lectin and complement mediate follicular localization and enhanced immunogenicity of diverse protein nanoparticle immunogens

Cell Reports(2022)10.1016/j.celrep.2021.110217

N/A

0DataRank · unranked

61 citations

Lori Won, John C. Kraft, Isaac Sappington, Aereas Aung, Shengwei Wu +7 more

Layer‐by‐layer interleukin‐12 nanoparticles drive a safe and effective response in ovarian tumors

Bioengineering & Translational Medicine(2022)10.1002/btm2.10453

N/A

0DataRank · unranked

38 citations

Sean G. Smith, Ivan S. Pires, Sonia Iyer, Ferenc Reinhardt, Mariane B. Melo +5 more

Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques

Science Translational Medicine(2022)10.1126/scitranslmed.abl9605

N/A

0DataRank · unranked

35 citations

Meng Yuan, Sean Callaghan, Rami Musharrafieh, Ge Song, Murillo Silva +33 more

Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies

Proceedings of the National Academy of Sciences(2022)10.1073/pnas.2205983119

N/A

0DataRank · unranked

32 citations

Yash Agarwal, Noor Momin, Sarah C. Cowles, Joseph R. Palmeri, Ellen Duong +8 more

Immunogenic cell stress and injury versus immunogenic cell death: implications for improving cancer treatment with immune checkpoint blockade

Molecular & Cellular Oncology(2022)10.1080/23723556.2022.2039038

N/A

0DataRank · unranked

2 citations

Tiffany R. Emmons, Lauren E. Milling, Darrell J. Irvine, Michael B Yaffe, Ganapathy Sriram

Identification of highly cross-reactive mimotopes for a public T cell response in murine melanoma

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.28.482028

N/A

0DataRank · unranked

1 citations

Coralie M. Backlund, Duncan M. Morgan, Byong H. Kang, Nishant K. Singh, Brooke D. Huisman +15 more

Human STING is a proton channel

Science(2023)10.1126/science.adf8974

N/A

0DataRank · unranked

205 citations

Rebecca J. Carlson, Ivan S. Pires, Matteo Gentili, Ellie Feng, Quentin Hellier +5 more

Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

Cell(2023)10.1016/j.cell.2023.06.002

N/A

0DataRank · unranked

204 citations

Alexander Hostetler, Duncan M. Morgan, Laura Maiorino, Ina Sulkaj, Charles A. Whittaker +12 more

Targeted modulation of immune cells and tissues using engineered biomaterials

Nature Reviews Bioengineering(2023)10.1038/s44222-022-00016-2

N/A

0DataRank · unranked

155 citations

Kaiyuan Ni, Darrell J. Irvine, Parisa Yousefpour

Universal redirection of CAR T cells against solid tumours via membrane-inserted ligands for the CAR

Nature Biomedical Engineering(2023)10.1038/s41551-023-01048-8

N/A

0DataRank · unranked

84 citations

Alexander Hostetler, Laura E. Chen, Vainavi Mukkamala, Wuhbet Abraham, Lucia T. Padilla +9 more

ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells

Cancer Cell(2023)10.1016/j.ccell.2023.11.004

N/A

0DataRank · unranked

51 citations

Wei‐Tien Tai, Andrea Aroldi, Carmen Mecca, Elisa Landoni, Manuel Nüesch +16 more

Biomaterials-Mediated Engineering of the Immune System

Annual Review of Immunology(2023)10.1146/annurev-immunol-101721-040259

N/A

0DataRank · unranked

44 citations

Sasan Jalili‐Firoozinezhad, B.J. Kim, Darrell J. Irvine, Coralie M. Backlund

A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates

Nature Communications(2023)10.1038/s41467-023-42923-x

N/A

0DataRank · unranked

24 citations

Kristen A. Rodrigues, Ester Marina-Zárate, Laura Maiorino, Bapi Pahar, Wen-Hsin Lee +31 more

Optimization of an alum-anchored clinical HIV vaccine candidate

npj Vaccines(2023)10.1038/s41541-023-00711-0

N/A

0DataRank · unranked

14 citations

Christopher A. Cottrell, Jon M. Steichen, Bettina Gröschel, Wuhbet Abraham, Heikyung Suh +8 more

Noninvasive In Vivo Imaging of T-Cells during Cancer Immunotherapy Using Rare-Earth Nanoparticles

ACS Nano(2023)10.1021/acsnano.3c03882

N/A

0DataRank · unranked

14 citations

Jifa Qi, Ching‐Wei Lin, Zhong‐Ming Li, Eric L. Dane, Archana Mahadevan Iyer +4 more

Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells

ACS Central Science(2023)10.1021/acscentsci.3c00625

N/A

0DataRank · unranked

13 citations

Aurélie Rondon, Simon L. Rössler, Cameron C. Hanna, Yehlin Cho, Binyou Wang +5 more

Anti–PD-1 and Extended Half-life IL2 Synergize for Treatment of Murine Glioblastoma Independent of Host MHC Class I Expression

Cancer Immunology Research(2023)10.1158/2326-6066.cir-22-0570

N/A

0DataRank · unranked

7 citations

Katayoun Ayasoufi, Delaney M. Wolf, Carley A. Owens, Courtney S. Malo, Benjamin Himes +14 more

Controlled lipid self-assembly for scalable manufacturing of next-generation immune stimulating complexes

Chemical Engineering Journal(2023)10.1016/j.cej.2023.142664

N/A

0DataRank · unranked

13 citations

Kaiyuan Ni, Mariane B. Melo, Na Li, Elana Ben‐Akiva, Laura Maiorino +8 more

Progress in vaccine development for infectious diseases—a Keystone Symposia report

Annals of the New York Academy of Sciences(2023)10.1111/nyas.14975

N/A

0DataRank · unranked

7 citations

Barney S. Graham, Richard A. Koup, Robert A. Seder, Katalin Karikó, Norbert Pardi +34 more

Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration

Nature(2023)10.1038/s41586-023-05741-1

N/A

0DataRank · unranked

18 citations

Henry J. Sutton, Christopher A. Cottrell, Ivy Phung, Gabriel Ozorowski, Leigh M. Sewall +33 more

Focusing antibody responses to the fusion peptide in rhesus macaques

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.06.26.545779

N/A

0DataRank · unranked

0 citations

Payal Pratap, Kimberly M. Cirelli, Diane G. Carnathan, Chiamaka A. Enemuo, Aleksandar Antanasijevic +19 more

Cancer tissue of origin constrains the growth and metabolism of metastases

Nature Metabolism(2024)10.1038/s42255-024-01105-9

N/A

0DataRank · unranked

34 citations

Yetiş Gültekin, Peter Winter, Sidney Y. Vermeulen, Konstantine Tchourine, Keene L. Abbott +22 more

Two-dose priming immunization amplifies humoral immunity by synchronizing vaccine delivery with the germinal center response

Science Immunology(2024)10.1126/sciimmunol.adl3755

N/A

0DataRank · unranked

26 citations

Leerang Yang, Jonathan Lam, Laura Maiorino, Elana Ben‐Akiva, Kristen A. Rodrigues +8 more

Carbohydrate-Lectin Interactions Reprogram Dendritic Cells to Promote Type 1 Anti-Tumor Immunity

ACS Nano(2024)10.1021/acsnano.4c07360

N/A

0DataRank · unranked

20 citations

Adele Gabba, Robert Hincapie, Sachin Bhagchandani, Ankit Basak, Mohammad Murshid Alam +7 more

Surfactant-Mediated Assembly of Precision-Size Liposomes

Chemistry of Materials(2024)10.1021/acs.chemmater.4c01127

N/A

0DataRank · unranked

15 citations

Jack R. Suggs, Isabella S. Carlo, Dong Soo Yun, Paula T. Hammond, Darrell J. Irvine +1 more

Vaccination with nanoparticles displaying gH/gL from Epstein-Barr virus elicits limited cross-protection against rhesus lymphocryptovirus

Cell Reports Medicine(2024)10.1016/j.xcrm.2024.101587

N/A

0DataRank · unranked

12 citations

Karina Schmidt, Leah J. Homad, Gargi Kher, Guoyue Xu, Kristen A. Rodrigues +9 more

Charge‐Stabilized Nanodiscs as a New Class of Lipid Nanoparticles

Advanced Materials(2024)10.1002/adma.202408307

N/A

0DataRank · unranked

9 citations

Alexander Hostetler, Gil Covarrubias, Isabella S. Carlo, Jack R. Suggs, B.J. Kim +5 more

Modulation of antigen delivery and lymph node activation in non-human primates by saponin adjuvant SMNP

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.28.608716

N/A

0DataRank · unranked

4 citations

Yiming J. Zhang, Laura Maiorino, Mariane B. Melo, Mariluz A. Arainga Ramirez, Sidath C. Kumarapperuma +18 more

“Target-and-release” nanoparticles for effective immunotherapy of metastatic ovarian cancer

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.07.05.602135

N/A

0DataRank · unranked

3 citations

Gil Covarrubias, Victoria F. Gomerdinger, Coralie M. Backlund, Apoorv Shanker, Ezra Gordon +7 more

Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.11.27.625755

N/A

0DataRank · unranked

3 citations

Christopher A. Cottrell, James C. Quinn, Diane G. Carnathan, Daniel Bader, Andy S. Tran +21 more

Directed evolution-based discovery of ligands for in vivo restimulation of CAR-T cells

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.04.16.589780

N/A

0DataRank · unranked

2 citations

Alexandra Neeser, Ranjani Ramasubramanian, Anna Romanov, Ryan Tannir, Naveen K. Mehta +23 more

Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.08.19.608655

N/A

0DataRank · unranked

2 citations

Yiming J. Zhang, Aereas Aung, Duncan M. Morgan, Laura Maiorino, Parisa Yousefpour +10 more

Glycan-costumed virus-like particles promote type 1 anti-tumor immunity

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.18.575711

N/A

0DataRank · unranked

1 citations

Adele Gabba, Robert Hincapie, Sachin Bhagchandani, A.K. Basak, Mohammad Murshid Alam +6 more

Data from: Vaccine targeting to mucosal lymphoid tissues promotes humoral immunity in the gastrointestinal tract

Open MIND(2024)10.5061/dryad.00000009x

N/A

0DataRank · unranked

0 citations

Suh, Heikyung, Parastoo Amlashi, Sergio A. Rodriguez‐Aponte, John Christopher Love, Darrell J. Irvine +4 more

Visualizing lipid nanoparticle trafficking for mRNA vaccine delivery in non-human primates

Molecular Therapy(2025)10.1016/j.ymthe.2025.01.008

N/A

0DataRank · unranked

44 citations

Mariluz Araínga, Laura Maiorino, Ivan S. Pires, Beomjoon Kim, Katarzyna Kaczmarek Michaels +9 more

Vaccination with an mRNA-encoded membrane-bound HIV envelope trimer induces neutralizing antibodies in animal models

Science Translational Medicine(2025)10.1126/scitranslmed.adw0721

N/A

0DataRank · unranked

28 citations

Christopher A. Cottrell, Ester Marina-Zárate, Alessia Liguori, Elise Landais, Jonathan L. Torres +40 more

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

Advanced Functional Materials(2025)10.1002/adfm.202503965

N/A

0DataRank · unranked

18 citations

Ezra Gordon, Heikyung Suh, Darrell J. Irvine, Paula T. Hammond, Ivan S. Pires

Diverse priming outcomes under conditions of very rare precursor B cells

Immunity(2025)10.1016/j.immuni.2025.03.003

N/A

0DataRank · unranked

14 citations

Ester Marina-Zárate, Kristen A. Rodrigues, Jon M. Steichen, Monolina Shil, Kaiyuan Ni +40 more

Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV

Cell(2025)10.1016/j.cell.2025.08.024

N/A

0DataRank · unranked

12 citations

Leah Froehle, Alexandra N Pipkin, Heeva Baharlou, Alice H. Linder, Palak Shah +24 more

The saponin monophosphoryl lipid A nanoparticle adjuvant induces dose-dependent HIV vaccine responses in nonhuman primates

Journal of Clinical Investigation(2025)10.1172/jci185292

N/A

0DataRank · unranked

11 citations

Ester Marina-Zárate, Laura Maiorino, Amber Myers, Katarzyna Kaczmarek Michaels, Ivan S. Pires +23 more

Scale-up and cGMP manufacturing of next-generation vaccine adjuvant saponin/MPLA nanoParticles (SMNP)

Journal of Pharmaceutical Sciences(2025)10.1016/j.xphs.2025.103913

N/A

0DataRank · unranked

10 citations

Ivan S. Pires, Mariane B. Melo, Dong Soo Yun, Andreas Wagner, Magdolna Budai +6 more

Highly functional and prolonged germinal center T follicular helper cell responses are associated with enhanced neutralizing antibody development

Immunity(2025)10.1016/j.immuni.2025.10.008

N/A

0DataRank · unranked

10 citations

Henry J. Sutton, Paul Lopez, Tasha K. Altheide, Michael Bick, Iszac Burton +13 more

HIV broadly neutralizing antibody precursors to the Apex epitope induced in nonhuman primates

Science Immunology(2025)10.1126/sciimmunol.adt6660

N/A

0DataRank · unranked

9 citations

Henry J. Sutton, Payal Pratap, Jon M. Steichen, Diane G. Carnathan, James C. Quinn +38 more

Simultaneous induction of multiple classes of broadly neutralizing antibody precursors by combination germline-targeting immunization in nonhuman primates

Science Immunology(2025)10.1126/sciimmunol.adu8878

N/A

0DataRank · unranked

5 citations

M. Krystal, Jon M. Steichen, Torben Schiffner, Tasha K. Altheide, Alessia Liguori +15 more

Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis

npj Vaccines(2025)10.1038/s41541-025-01218-6

N/A

0DataRank · unranked

3 citations

Elena Gustchina, Javier Guenaga, Victor Ayala, Wen-Hsin Lee, Gabriel Ozorowski +15 more

Directed evolution-based discovery of ligands for in vivo restimulation of chimeric antigen receptor T cells

Nature Biomedical Engineering(2025)10.1038/s41551-025-01470-0

N/A

0DataRank · unranked

3 citations

Alexandra Neeser, Ranjani Ramasubramanian, Anna Romanov, Ryan Tannir, Naveen K. Mehta +23 more

Surface Avidity of Anionic Polypeptide Coatings on Layer‐by‐Layer Nanoparticles Target Cancer‐Associated Amino Acid Transporters

Angewandte Chemie International Edition(2025)10.1002/anie.202519203

N/A

0DataRank · unranked

2 citations

Margaret M. Billingsley, Ezra Gordon, Andrew J. Pickering, Eva Cai, Gonzalo J. Esparza +6 more

Vaccination of nonhuman primates elicits a broadly neutralizing antibody lineage targeting a quaternary epitope on the HIV-1 Env trimer

Immunity(2025)10.1016/j.immuni.2025.04.010

N/A

0DataRank · unranked

4 citations

Shridhar Bale, Javier Guenaga, Gabriel Ozorowski, Mónika Ádori, Xiaohe Lin +25 more

Augmented humoral responses to HIV Env trimers delivered as transmembrane immunogens by self-replicating RNA

Molecular Therapy(2025)10.1016/j.ymthe.2025.07.036

N/A

0DataRank · unranked

2 citations

Amrit Raj Ghosh, Himanshi Chawla, Rachel Yeung, Justin M. Gregory, Keyi Si +12 more

Priming VRC01-precursor B cells with non-envelope immunogens disfavors boosting with HIV-1 envelope

npj Vaccines(2025)10.1038/s41541-025-01235-5

N/A

0DataRank · unranked

1 citations

Yu-Hsin Wan, Samuel C. Scharffenberger, Crystal B. Chhan, A. Davis, Leah J. Homad +10 more

Vaccination with mRNA-encoded membrane-bound HIV Envelope trimer induces neutralizing antibodies in animal models

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.01.24.634423

N/A

0DataRank · unranked

5 citations

Christopher A. Cottrell, Ester Marina-Zárate, Alessia Liguori, Elise Landais, Jonathan L. Torres +40 more

Engineering gene expression dynamics via self-amplifying RNA with drug-responsive non-structural proteins

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.08.658495

N/A

0DataRank · unranked

5 citations

Justin R. Gregory, Keyi Si, Jan Lonzarić, Yingzhong Li, Junmin Wang +14 more

Consistent Induction of Broadly Neutralizing HIV Antibodies by a Novel Two-Step Mechanism Informs Immunogen Design

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.10.06.680687

N/A

0DataRank · unranked

3 citations

Harry B. Gristick, Hui Li, Edem Gavor, Andrew J. Connell, Edward F. Kreider +52 more

Surface avidity of anionic polypeptide coatings target nanoparticles to cancer-associated amino acid transporters

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.07.28.667320

N/A

0DataRank · unranked

1 citations

Margaret M. Billingsley, Ezra Gordon, Andrew Pickering, Eva Cai, Gonzalo J. Esparza +5 more

A modular protocol for virosome display of subunit vaccine antigens

STAR Protocols(2025)10.1016/j.xpro.2025.103610

N/A

0DataRank · unranked

0 citations

Lindsey Adams, Ashraf S. Yousif, Maya Sangesland, Larance Ronsard, Vintus Okonkwo +5 more

ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells

UNC Libraries(2025)10.17615/thhw-qy46

N/A

0DataRank · unranked

0 citations

Manuel Nüesch, Elisa Landoni, Tongqing Li, Luca Molinaro, Andrea Aroldi +16 more

Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques

npj Vaccines(2025)10.1038/s41541-025-01252-4

N/A

0DataRank · unranked

0 citations

Christopher A. Cottrell, James C. Quinn, Diane G. Carnathan, Daniel Bader, Andy S. Tran +21 more

Rapid elicitation of a new class of neutralizing N332-glycan independent V3-glycan antibodies against HIV-1 in nonhuman primates

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.04.674340

N/A

0DataRank · unranked

0 citations

Jianqiu Du, Zi Jie Lin, Margaret Kerwin, Marta Tarquis-Medina, Eduardo Urbano +19 more

Multifaceted Effects of Antigen Valency on B Cell Response Composition and Differentiation In Vivo

Immunity(2020)10.1016/j.immuni.2020.08.001

N/A

0DataRank · unranked

284 citations

Robert Abbott, Brian L. Freeman, Sonya Haupt, Bettina Gröschel, Murillo Silva +5 more

Surface Avidity of Anionic Polypeptide Coatings on Layer‐by‐Layer Nanoparticles Target Cancer‐Associated Amino Acid Transporters

Angewandte Chemie(2025)10.1002/ange.202519203

N/A

0DataRank · unranked

0 citations

Margaret M. Billingsley, Ezra Gordon, Andrew J. Pickering, Eva Cai, Gonzalo J. Esparza +6 more

Engineered immunogen binding to alum adjuvant enhances humoral immunity

Nature Medicine(2020)10.1038/s41591-020-0753-3

N/A

0DataRank · unranked

268 citations

Yu Kato, Wuhbet Abraham, Jason Y.H. Chang, Daniel W. Kulp, Nicki Watson +17 more

Controlling timing and location in vaccines

Advanced Drug Delivery Reviews(2020)10.1016/j.addr.2020.06.019

N/A

0DataRank · unranked

262 citations

Aereas Aung, Murillo Silva, Darrell J. Irvine

Shaping humoral immunity to vaccines through antigen-displaying nanoparticles

Current Opinion in Immunology(2020)10.1016/j.coi.2020.01.007

N/A

0DataRank · unranked

137 citations

Benjamin J. Read, Darrell J. Irvine

Regulatory T cells engineered with TCR signaling–responsive IL-2 nanogels suppress alloimmunity in sites of antigen encounter

Science Translational Medicine(2020)10.1126/scitranslmed.aaw4744

N/A

0DataRank · unranked

99 citations

Ina Sulkaj, Mariane B. Melo, Na Li, Hazim Allos, Juliano Alhaddad +20 more

Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

Science Immunology(2020)10.1126/sciimmunol.abc2728

N/A

0DataRank · unranked

86 citations

Ashwin Somasundaram, Jessica Moskovitz, Andrea L. Szymczak-Workman, Chang Liu, Anthony R. Cillo +12 more

Cytoskeletal tension actively sustains the migratory T‐cell synaptic contact

The EMBO Journal(2020)10.15252/embj.2019102783

N/A

0DataRank · unranked

78 citations

Michael Mak, Yeh‐Chuin Poh, Mira Tohmé, Nicki Watson, Mariane B. Melo +5 more

ABC triblock bottlebrush copolymer-based injectable hydrogels: design, synthesis, and application to expanding the therapeutic index of cancer immunochemotherapy

Chemical Science(2020)10.1039/d0sc02611e

N/A

0DataRank · unranked

74 citations

Lauren E. Milling, Qixian Chen, Wenxu Zhang, Sachin Bhagchandani, Hung V.‐T. Nguyen +3 more

Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations

npj Vaccines(2020)10.1038/s41541-020-00223-1

N/A

0DataRank · unranked

71 citations

Christopher A. Cottrell, Aleksandar Antanasijevic, Diane G. Carnathan, Benjamin Cossette, Chiamaka A. Enemuo +19 more

Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines

Nature Biomedical Engineering(2020)10.1038/s41551-020-0563-4

N/A

0DataRank · unranked

66 citations

Roma Pradhan, Ava P. Soleimany, Kelly D. Moynihan, Adrienne M. Rothschilds, Noor Momin +6 more

In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation

Molecular Therapy(2020)10.1016/j.ymthe.2020.11.010

N/A

0DataRank · unranked

36 citations

Joyca De Temmerman, Tasuku Kitada, Jacob Becraft, Ron Weiss, Darrell J. Irvine +5 more

Role of nanoscale antigen organization on B-cell activation probed using DNA origami

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.16.951475

N/A

0DataRank · unranked

30 citations

Tyson J. Moyer, Matthew B. Stone, Tyson R. Shepherd, William R. Schief, Darrell J. Irvine +2 more

Targeting HIV Env immunogens to B cell follicles in non-human primates through immune complex or protein nanoparticle formulations

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.02.19.956482

N/A

0DataRank · unranked

8 citations

Christopher A. Cottrell, Aleksandar Antanasijevic, Diane G. Carnathan, Benjamin Cossette, Chiamaka A. Enemuo +17 more

Author Correction: A Engineered immunogen binding to alum adjuvant enhances humoral immunity

Nature Medicine(2020)10.1038/s41591-020-0861-0

N/A

0DataRank · unranked

6 citations

Yu Kato, Wuhbet Abraham, Jason Y.H. Chang, Daniel W. Kulp, Nicki Watson +17 more

Controlling wireframe DNA origami nuclease degradation with minor groove binders

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.05.24.110783

N/A

0DataRank · unranked

4 citations

Hellen Huang, Benjamin J. Read, Eric Ginsburg, William R. Schief, Nicholas P. Farrell +3 more