🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge

Fostering Data Sharing

Search Papers Authors Institutions Grants FAIR About

TheSindex

Fostering Data Sharing

Empowering the data sharing that empowers science — an open, citation-grounded index for datasets.

Product

Search
API
Explore
Rankings

Resources

Methodology
Data Sources
Documentation
Press

Organization

About
Team
Wikidata

© 2026 theSindex. All rights reserved.

Home
Authors
Dennis W. Dickson

Dennis W. Dickson

Mayo Clinic in Florida

ORCID: 0000-0001-7189-7917

MedicineNeuroscience

Pilot corpus only

This score is computed over theSindex pilot corpus and does not cover the full scientific literature. Scores are relative to papers we have ingested — papers, authors, and institutions outside the pilot are not represented. Methodology.

Top 1%percentile

7.1Author DataRank

Indexed papers

12in pilot corpus

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Why this DataRank?

An author's DataRank is the sum of the DataRanks of all 12 indexed papers attributed to them. A prolific author with many moderate-impact papers can outrank one with a single high-impact paper.

Author scores recompute whenever paper DataRanks are refreshed, so this number lags the underlying paper scores by at most one batch run.

Read the full methodology →

Top data-sharing exemplar

The highest-impact dataset this researcher has shared, ranked by DataRank — the single contribution doing the most to lift their data-sharing standing.

Deciphering cellular transcriptional alterations in Alzheimer’s disease brains

Molecular Neurodegeneration(2020)10.1186/s13024-020-00392-6

Top 12%

1.8DataRank

Top 12%70 citations

Mariet Allen, Shaoyu Li, Zachary Quicksall, Tulsi Patel, Troy Carnwath +10 more

Papers

Driven by 251 papers — median percentile 60. Top paper: “Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation”.

Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation

Nature Medicine(2020)10.1038/s41591-020-0815-6

N/A

8.1DataRank · unranked

1076 citations

Eric B. Dammer, Duc M. Duong, Lingyan Ping, Maotian Zhou, Luming Yin +28 more

Deciphering cellular transcriptional alterations in Alzheimer’s disease brains

Molecular Neurodegeneration(2020)10.1186/s13024-020-00392-6

Top 12%

1.8DataRank

Top 12%70 citations

Mariet Allen, Shaoyu Li, Zachary Quicksall, Tulsi Patel, Troy Carnwath +10 more

Genome sequence analyses identify novel risk loci for multiple system atrophy

Neuron(2024)10.1016/j.neuron.2024.04.002

N/A

1.7DataRank · unranked

45 citations

Anindita Ray, Zalak Shah, Jinhui Ding, Paola Ruffo, Masashi Fujita +95 more

Single-cell dissection of the human motor and prefrontal cortices in ALS and FTLD

Cell(2024)10.1016/j.cell.2024.02.031

Top 13%

1.7DataRank

Top 13%95 citations

Hyeseung Lee, Maria J. Ulloa-Navas, Raleigh M. Linville, Francisco J. Garcia, Kyriakitsa Galani +22 more

Validation Study of the MDS Criteria for the Diagnosis of Multiple System Atrophy in the Mayo Clinic Brain Bank

Neurology(2023)10.1212/wnl.0000000000207905

N/A

1.5DataRank · unranked

35 citations

Shunsuke Koga, Aya Murakami, Miki Kawazoe, Minji Kim, Nicholas B. Martin +5 more

Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups

Brain(2021)10.1093/brain/awab402

N/A

1.4DataRank · unranked

66 citations

Zalak Shah, Ruth Chia, Sandra E. Black, Ziv Gan‐Or, Julia Keith +81 more

The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease

Alzheimer's & Dementia(2011)10.1016/j.jalz.2011.03.008

N/A

1.4DataRank · unranked

10055 citations

Steven T. DeKosky, Bruno Dubois, Howard H. Feldman, Nick C. Fox, Anthony Gamst +11 more

Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease

Alzheimer s & Dementia(2021)10.1002/alz.12254

Top 15%

1.4DataRank

Top 15%42 citations

Cory C. Funk, Karen N. McFarland, Eric B. Dammer, Mariet Allen, Minerva M. Carrasquillo +15 more

Effect Modifiers of TDP-43-Associated Hippocampal Atrophy Rates in Patients with Alzheimer’s Disease Neuropathological Changes

Journal of Alzheimer s Disease(2020)10.3233/jad-191040

N/A

1.2DataRank · unranked

36 citations

Alexandra Wennberg, Stephen D. Weigand, Melissa E. Murray, Matthew L. Senjem, Anthony J. Spychalla +10 more

Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy

Journal of Neuropathology & Experimental Neurology(2020)10.1093/jnen/nlaa153

N/A

1.2DataRank · unranked

71 citations

Timothy E. Richardson, Kurt Farrell, Megan A. Iida, Chan Foong, Ping Shang +52 more

Clinical and pathological characteristics of later onset multiple system atrophy

Journal of Neurology(2022)10.1007/s00415-022-11067-1

N/A

1.0DataRank · unranked

20 citations

Shunsuke Koga, Yoshihisa Otsuka, Norio Chihara, Takehiro Ueda, Kenji Sekiguchi +5 more

A molecular pathology, neurobiology, biochemical, genetic and neuroimaging study of progressive apraxia of speech

Nature Communications(2021)10.1038/s41467-021-23687-8

N/A

1.0DataRank · unranked

71 citations

Joseph R. Duffy, Heather M. Clark, Rene L. Utianski, Edythe A. Strand, Mary M. Machulda +24 more

TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A

Nature(2022)10.1038/s41586-022-04424-7

N/A

0.957DataRank · unranked

589 citations

Mercedes Prudencio, Yuka Koike, Sarat C. Vatsavayai, Garam Kım, Fred Harbinski +30 more

Clinical criteria for a limbic-predominant amnestic neurodegenerative syndrome

Brain Communications(2024)10.1093/braincomms/fcae183

N/A

0.914DataRank · unranked

36 citations

Hugo Botha, Jonathan Graff‐Radford, Aaron Switzer, Scott A. Przybelski, Heather J. Wiste +18 more

TDP-43 Pathology in Alzheimer’s Disease

Molecular Neurodegeneration(2021)10.1186/s13024-021-00503-x

N/A

0.890DataRank · unranked

377 citations

Shunsuke Koga, Justin O’Leary, Dennis W. Dickson, Guojun Bu, Na Zhao +1 more

Staging TDP-43 pathology in Alzheimer’s disease

Acta Neuropathologica(2014)10.1007/s00401-013-1211-9

N/A

0.890DataRank · unranked

377 citations

Melissa E. Murray, Jennifer L. Whitwell, Joseph E. Parisi, Leonard Petrucelli, Clifford R. Jack +3 more

TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia

Science Translational Medicine(2024)10.1126/scitranslmed.adf9735

N/A

0.889DataRank · unranked

51 citations

Virginia Estades Ayuso, Yari Carlomagno, Mei Yue, Tiffany W. Todd, Ying Hao +31 more

Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case–control study

The Lancet Neurology(2011)10.1016/s1474-4422(11)70175-2

N/A

0.876DataRank · unranked

343 citations

Michael G. Heckman, Nadine Abahuni, Grazia Annesi, Justin A. Bacon, Soraya Bardien +60 more

Neuropathology and molecular diagnosis of Synucleinopathies

Molecular Neurodegeneration(2021)10.1186/s13024-021-00501-z

N/A

0.875DataRank · unranked

341 citations

Hiroaki Sekiya, Naveen Kondru, Owen A. Ross, Dennis W. Dickson, Shunsuke Koga

Microglial lysosome dysfunction contributes to white matter pathology and TDP-43 proteinopathy in GRN-associated FTD

Cell Reports(2021)10.1016/j.celrep.2021.109581

N/A

0.673DataRank · unranked

88 citations

Wei Shao, Tiffany W. Todd, Jimei Tong, Mei Yue, Shunsuke Koga +9 more

Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy

Molecular Neurodegeneration(2024)10.1186/s13024-024-00747-3

N/A

0.665DataRank · unranked

26 citations

Timothy S. Chang, Beth A. Dombroski, Po‐Liang Cheng, Vishakha Patil, Leopoldo Valiente‐Banuet +57 more

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36

Neuron(2020)10.1016/j.neuron.2020.04.011

N/A

0.655DataRank · unranked

78 citations

Tania F. Gendron, Nisha Raj, María García-Murias, Anwesha Banerjee, Ryan H. Purcell +30 more

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

Cell(2024)10.1016/j.cell.2024.03.015

N/A

0.654DataRank · unranked

77 citations

Alice Maria Giani, Jesus Madero-Perez, Zeping Zhao, Yuansong Wan, Avi J. Samelson +24 more

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders

Cell Reports Medicine(2022)10.1016/j.xcrm.2022.100607

N/A

0.641DataRank · unranked

71 citations

Michael G. Heckman, Launia J. White, Austin M. Veire, Otto Pedraza, Alexander R. Burch +77 more

Loss of Tmem106b exacerbates FTLD pathologies and causes motor deficits in progranulin‐deficient mice

EMBO Reports(2020)10.15252/embr.202050197

N/A

0.635DataRank · unranked

68 citations

Mieu Brooks, Peizhou Jiang, Shunsuke Koga, Aamir Zuberi, Matthew Baker +11 more

The temporal onset of the core features in dementia with Lewy bodies

Alzheimer s & Dementia(2021)10.1002/alz.12411

N/A

0.617DataRank · unranked

60 citations

Jonathan Graff‐Radford, Jeremiah A. Aakre, Lincoln Wurtz, David S. Knopman, Neill R. Graff‐Radford +18 more

Clinical Deep Phenotyping of ABCA7 Mutation Carriers

Neurology Genetics(2022)10.1212/nxg.0000000000000655

Top 33%

0.603DataRank

Top 33%15 citations

Charlotte C.G. Ho, Merve Atık, Mariet Allen, Sarah Lincoln, Kimberly Malphrus +10 more

Amyloid PET detects the deposition of brain Aβ earlier than CSF fluid biomarkers

Alzheimer s & Dementia(2024)10.1002/alz.14317

N/A

0.584DataRank · unranked

19 citations

Carly Mester, Emily S. Lundt, Jeyeon Lee, Sujala Ghatamaneni, Alicia Algeciras‐Schimnich +19 more

Single-cell profiling of the human primary motor cortex in ALS and FTLD

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.07.07.451374

N/A

0.564DataRank · unranked

42 citations

Hyeseung Lee, Brent E. Fitzwalter, Shahin Mohammadi, Luc Pregent, Mahammad Gardashli +20 more

Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies

Acta Neuropathologica Communications(2020)10.1186/s40478-020-0879-z

N/A

0.564DataRank · unranked

42 citations

Dena G. Hernandez, Owen A. Ross, Célia Kun‐Rodrigues, Lee Darwent, Claire E. Shepherd +47 more

Gliovascular transcriptional perturbations in Alzheimer’s disease reveal molecular mechanisms of blood brain barrier dysfunction

Nature Communications(2024)10.1038/s41467-024-48926-6

N/A

0.557DataRank · unranked

40 citations

Xue Wang, Joseph S. Reddy, Yuhao Min, Elanur Yılmaz, Prabesh Bhattarai +36 more

Genome-wide association study and functional validation implicates JADE1 in tauopathy

Acta Neuropathologica(2021)10.1007/s00401-021-02379-z

N/A

0.553DataRank · unranked

39 citations

SoongHo Kim, Natalia Han, Megan A. Iida, Elias Gonzalez, Marcos Otero‐García +84 more

Interpretable deep learning of myelin histopathology in age-related cognitive impairment

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01425-5

N/A

0.542DataRank · unranked

36 citations

Gabriel A. Marx, Daniel Koenigsberg, Mary Sawyer, Megan A. Iida, Jamie M. Walker +59 more

Population‐specific frequencies for LRRK2 susceptibility variants in the genetic epidemiology of Parkinson's disease (GEO‐PD) consortium

Movement Disorders(2013)10.1002/mds.25600

N/A

0.538DataRank · unranked

35 citations

Alexandra I. Soto‐Ortolaza, Nadine Abahuni, Grazia Annesi, Justin A. Bacon, Soraya Bardien +65 more

Long-read targeted sequencing uncovers clinicopathological associations forC9orf72-linked diseases

Brain(2021)10.1093/brain/awab006

N/A

0.524DataRank · unranked

32 citations

Ross A. Aleff, Jazmyne L. Jackson, NiCole A. Finch, Matthew Baker, Tania F. Gendron +17 more

Genome-wide structural variant analysis identifies risk loci for non-Alzheimer’s dementias

Cell Genomics(2023)10.1016/j.xgen.2023.100316

N/A

0.524DataRank · unranked

32 citations

Ruth Chia, Jinhui Ding, Memoona Rasheed, Masashi Fujita, Vilas Menon +88 more

Clinicopathologic and genetic features of multiple system atrophy with Lewy body disease

Brain Pathology(2020)10.1111/bpa.12839

N/A

0.510DataRank · unranked

29 citations

Fuyao Li, Na Zhao, Shanu F. Roemer, Tanis J. Ferman, Anna I. Wernick +7 more

Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer’s disease related proteins

Molecular Neurodegeneration(2023)10.1186/s13024-022-00592-2

N/A

0.500DataRank · unranked

27 citations

Joseph S. Reddy, Zachary Quicksall, Minerva M. Carrasquillo, Xue Wang, Chia‐Chen Liu +22 more

Deciphering cellular transcriptional alterations in Alzheimer’s disease brains

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.04.15.041376

Top 39%

0.495DataRank

Top 39%9 citations

Mariet Allen, Shaoyu Li, Zachary Quicksall, Tulsi Patel, Troy Carnwath +10 more

Impact of cardiovascular risk factors on plasma biomarkers in prediction of Alzheimer's and cerebrovascular neuropathology

The Journal of Prevention of Alzheimer s Disease(2025)10.1016/j.tjpad.2025.100224

N/A

0.472DataRank · unranked

9 citations

Jeremy A. Syrjanen, Nikki H. Stricker, Alicia Algeciras-Schimnich, Naomi Kouri, Walter K. Kremers +14 more

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer’s disease

Genome biology(2025)10.1186/s13059-025-03564-z

Top 41%

0.467DataRank

Top 41%16 citations

Penelope Benchek, Giuseppe Tosto, Nicholas A. Kushch, Jin Sha, Katrina Bazemore +95 more

Shared brain transcriptomic signature in TDP-43 type A FTLD patients with or without GRN mutations

Brain(2021)10.1093/brain/awab437

N/A

0.464DataRank · unranked

21 citations

Ligia Mateiu, Matthew Baker, Mariely DeJesus‐Hernandez, Cristina T. Vicente, NiCole A. Finch +15 more

MAPT subhaplotypes in corticobasal degeneration: assessing associations with disease risk, severity of tau pathology, and clinical features

Acta Neuropathologica Communications(2020)10.1186/s40478-020-01097-z

N/A

0.464DataRank · unranked

21 citations

Shunsuke Koga, Ronald L. Walton, Alexandra I. Soto‐Beasley, Naomi Kouri, Michael DeTure +10 more

Influences of amyloid-β and tau on white matter neurite alterations in dementia with Lewy bodies

npj Parkinson s Disease(2024)10.1038/s41531-024-00684-4

N/A

0.458DataRank · unranked

13 citations

Robert I. Reid, Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem +24 more

Frequency of Comorbid Pathologies and Their Clinical Impact in Multiple System Atrophy

Movement Disorders(2023)10.1002/mds.29670

N/A

0.457DataRank · unranked

20 citations

Shunsuke Koga, Aya Murakami, Michael DeTure, Owen A. Ross, Ryan J. Uitti +4 more

Neuropathological changes and amyloid-related imaging abnormalities in Alzheimer's disease treated with aducanumab versus untreated: a retrospective case–control study

The Lancet Neurology(2025)10.1016/s1474-4422(25)00313-8

N/A

0.449DataRank · unranked

19 citations

Yoav Piura, Christina M. Moloney, Jessica L Chalk, Sarah Lincoln, Matthew H. Rutledge +16 more

LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry

Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad059

N/A

0.449DataRank · unranked

19 citations

David W. Fardo, Lincoln M. P. Shade, James D. Bowen, Paul K. Crane, Gail P. Jarvik +94 more

The frequency and distribution of TDP-43 pathology in argyrophilic grain disease

Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad042

N/A

0.449DataRank · unranked

19 citations

Aya Murakami, Nicholas B. Martin, Dennis W. Dickson, Shunsuke Koga

TDP-43-dependent mis-splicing of KCNQ2 triggers intrinsic neuronal hyperexcitability in ALS/FTD

Nature Neuroscience(2025)10.1038/s41593-025-02096-w

N/A

0.442DataRank · unranked

18 citations

Kelly A. Marshall, Peter Harley, Jacob R. Mann, Francesco Alessandrini, Carlos G. Vanoye +32 more

Common Variants Near ZIC1 and ZIC4 in Autopsy‐Confirmed Multiple System Atrophy

Movement Disorders(2022)10.1002/mds.29164

N/A

0.434DataRank · unranked

17 citations

Anja Tietz, Viktoria Ruf, Owen A. Ross, Shunsuke Koga, Dennis W. Dickson +67 more

A multimodal clinical diagnostic approach using MRI and 18F-FDG-PET for antemortem diagnosis of TDP-43 in cases with low–intermediate Alzheimer’s disease neuropathologic changes and primary age-related tauopathy

Journal of Neurology(2024)10.1007/s00415-024-12312-5

N/A

0.426DataRank · unranked

8 citations

Nha Trang Thu Pham, Cynthia J. Vernon, Arenn F. Carlos, Ronald C. Petersen, Dennis W. Dickson +5 more

Loss of Tmem106b leads to cerebellum Purkinje cell death and motor deficits

Brain Pathology(2021)10.1111/bpa.12945

N/A

0.425DataRank · unranked

16 citations

Alexandra M. Nicholson, Yingxue Ren, Shunsuke Koga, Hung Phuoc Nguyen, Mieu Brooks +18 more

TDP-43-associated atrophy in brains with and without frontotemporal lobar degeneration

NeuroImage Clinical(2022)10.1016/j.nicl.2022.102954

N/A

0.425DataRank · unranked

16 citations

Peter R. Martin, Nirubol Tosakulwong, Melissa E. Murray, Leonard Petrucelli, Matthew L. Senjem +11 more

Amyloid-β predominant Alzheimer’s disease neuropathologic change

Brain(2024)10.1093/brain/awae325

N/A

0.425DataRank · unranked

16 citations

Yuriko Katsumata, Xian Wu, Khine Zin Aung, David W. Fardo, Shelley L. Forrest +95 more

TDP-43 Is Associated with Subiculum and Cornu Ammonis 1 Hippocampal Subfield Atrophy in Primary Age-Related Tauopathy

Journal of Alzheimer s Disease(2024)10.3233/jad-240136

N/A

0.408DataRank · unranked

10 citations

Rodolfo G. Gatto, Nha Trang Thu Pham, Ronald C. Petersen, Mary M. Machulda, R. Ross Reichard +5 more

Histologic lesion type correlates of magnetic resonance imaging biomarkers in four-repeat tauopathies

Brain Communications(2022)10.1093/braincomms/fcac108

N/A

0.406DataRank · unranked

14 citations

Nirubol Tosakulwong, Stephen D. Weigand, Marina Buciuc, Farwa Ali, Heather M. Clark +12 more

Transcriptional mutagenesis of α-synuclein caused by DNA oxidation in Parkinson’s disease pathogenesis

Acta Neuropathologica(2023)10.1007/s00401-023-02632-7

N/A

0.385DataRank · unranked

12 citations

Minkyung Song, Levi Adams, Inhye Jeong, Goun Je, Subhrangshu Guhathakurta +12 more

Investigation of the genetic aetiology of Lewy body diseases with and without dementia

Brain Communications(2024)10.1093/braincomms/fcae190

N/A

0.385DataRank · unranked

12 citations

Raquel Real, Alejandro Martínez-Carrasco, Ruth Chia, Michael Lawton, Maryam Shoai +93 more

Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies

Molecular Neurodegeneration(2025)10.1186/s13024-025-00817-0

N/A

0.373DataRank · unranked

11 citations

Melissa C. Wren, Feilin Liu, Naomi Kouri, Anastasiia Maistrenko, Bilal Khalil +9 more

Histologic tau lesions and magnetic resonance imaging biomarkers differ across two progressive supranuclear palsy variants

Brain Communications(2024)10.1093/braincomms/fcae113

N/A

0.360DataRank · unranked

10 citations

Arenn F. Carlos, Farwa Ali, Heather M. Clark, Joseph R. Duffy, Rene L. Utianski +12 more

Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy

medRxiv(2023)10.1101/2023.12.28.23300612

N/A

0.351DataRank · unranked

8 citations

Timothy S. Chang, Beth A. Dombroski, Po‐Liang Cheng, Vishakha Patil, Leopoldo Valiente‐Banuet +56 more

APOE2 Exacerbates TDP‐43 Related Toxicity in the Absence of Alzheimer Pathology

Annals of Neurology(2022)10.1002/ana.26580

N/A

0.345DataRank · unranked

9 citations

Shunsuke Koga, Zonghua Li, Justin O’Leary, Fuyao Li, Kai Chen +23 more

Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups

Acta Neuropathologica(2024)10.1007/s00401-024-02778-y

N/A

0.330DataRank · unranked

8 citations

Dolly Reyes‐Dumeyer, Angel Piriz, Patricia Recio, Diones Rivera Mejía, Martin Medrano +20 more

A limbic-predominant amnestic neurodegenerative syndrome associated with TDP-43 pathology

medRxiv(2023)10.1101/2023.11.19.23298314

N/A

0.318DataRank · unranked

4 citations

Hugo Botha, Jonathan Graff‐Radford, Aaron Switzer, Scott A. Przybelski, Heather J. Wiste +18 more

Genome‐wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease

Alzheimer s & Dementia(2025)10.1002/alz.70198

N/A

0.312DataRank · unranked

7 citations

Michael G. Heckman, Fabienne C. Fiesel, Shunsuke Koga, Alexandra I. Soto‐Beasley, Jens O. Watzlawik +14 more

Association of mitochondrial genomic background with risk of Multiple System Atrophy

Parkinsonism & Related Disorders(2020)10.1016/j.parkreldis.2020.10.040

N/A

0.312DataRank · unranked

7 citations

Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto‐Beasley, Ronald L. Walton, Shunsuke Koga +5 more

Uncovering the distinct macro-scale anatomy of dysexecutive and behavioural degenerative diseases

Brain(2023)10.1093/brain/awad356

N/A

0.292DataRank · unranked

6 citations

Leland R Barnard, Hugo Botha, Jonathan Graff‐Radford, Vijay K. Ramanan, Jeyeon Lee +13 more

Association of cardiovascular disease management drugs with Lewy body dementia: a case–control study

Brain Communications(2023)10.1093/braincomms/fcad346

N/A

0.292DataRank · unranked

6 citations

Brian Moroz, Sara Sáez-Atiénzar, Ruth Chia, Elizabeth K. Cahoon, Clifton L. Dalgard +93 more

Phase 1, Dose Escalation, Nonrandomized, Open-Label, Clinical Trial Evaluating the Safety and Preliminary Efficacy of Allogenic Adipose-Derived Mesenchymal Stem Cells for Recurrent Glioblastoma: A Clinical Trial Protocol

Neurosurgery Open(2023)10.1227/neuprac.0000000000000062

N/A

0.269DataRank · unranked

5 citations

Rawan Al‐kharboosh, Erin Twohy, Aleeshba Basil, Ewa Szymkiewicz, Abba C. Zubair +12 more

Diffuse argyrophilic grain disease with TDP-43 proteinopathy and neuronal intermediate filament inclusion disease: FTLD with mixed tau, TDP-43 and FUS pathologies

Acta Neuropathologica Communications(2023)10.1186/s40478-023-01611-z

N/A

0.269DataRank · unranked

5 citations

Aya Murakami, Alexandra I. Soto‐Beasley, Ronald L. Walton, Matthew Baker, Monica Castanedes‐Casey +4 more

Investigating the feasibility of 18F‐flortaucipir PET imaging in the antemortem diagnosis of primary age‐related tauopathy (PART): An observational imaging‐pathological study

Alzheimer s & Dementia(2024)10.1002/alz.14301

N/A

0.266DataRank · unranked

3 citations

Ryota Satoh, Nha Trang Thu Pham, Aivi T. Nguyen, Clifford R. Jack, Ronald C. Petersen +6 more

Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells

Movement Disorders(2025)10.1002/mds.30150

N/A

0.241DataRank · unranked

4 citations

Timothy S. Chang, Beth A. Dombroski, Po‐Liang Cheng, Yaqin Si, Albert Tucci +62 more

Genome-wide association study of neuropathological features in Lewy body disease

Brain(2025)10.1093/brain/awaf105

Top 61%

0.241DataRank

Top 61%4 citations

Shunsuke Koga, Alexandra I. Soto‐Beasley, Daisuke Ono, Mikolaj A. Wieczorek, Patrick W. Johnson +29 more

Association between antemortem plasma and structural MRI biomarkers and postmortem tau pathology in the Mayo Clinic Study of Aging

Alzheimer s Research & Therapy(2025)10.1186/s13195-025-01852-1

N/A

0.241DataRank · unranked

4 citations

Christina M. Moloney, Scott A. Przybelski, Alicia Algeciras‐Schimnich, Terry M. Therneau, Angela J. Fought +13 more

Upper motor neuron‐predominant motor neuron disease presenting as atypical parkinsonism: A clinicopathological study

Brain Pathology(2024)10.1111/bpa.13286

N/A

0.208DataRank · unranked

3 citations

Shunsuke Koga, Shinsuke Fujioka, Adrianna White, Kevin F. Bieniek, Hiroaki Sekiya +9 more

PPM1M, an LRRK2-counteracting, phosphoRab12-preferring phosphatase with a potential link to Parkinson’s disease

Cell Reports(2025)10.1016/j.celrep.2025.116031

N/A

0.208DataRank · unranked

3 citations

Neringa Pratuseviciute, Yu‐En Lin, Ayan Adhikari, Wondwossen M Yeshaw, Chloe Flitton +19 more

Correction: Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy

Molecular Neurodegeneration(2024)10.1186/s13024-024-00763-3

N/A

0.189DataRank · unranked

2 citations

Timothy S. Chang, Beth A. Dombroski, Po‐Liang Cheng, Vishakha Patil, Leopoldo Valiente‐Banuet +57 more

Novel differentially expressed genes and multiple biological pathways for Alzheimer's disease identified in brain tissue from African American donors

Alzheimer s & Dementia(2025)10.1002/alz.70629

Top 67%

0.172DataRank

Top 67%2 citations

Adam Labadorf, Nicholas K. O’Neill, Dennis W. Dickson, Brittany N. Dugger, Margaret E. Flanagan +21 more

MU-BRAIN: MUltiethnic Brain Rna-seq for Alzheimer INitiative

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.02.20.581250

Top 70%

0.165DataRank

Top 70%2 citations

Basilio Cieza, Dolly Reyes‐Dumeyer, Annie Lee, Yiyi Ma, Elanur Yılmaz +22 more

PPM1M, a LRRK2-counteracting, phosphoRab12-preferring phosphatase with potential link to Parkinson’s disease

10.1101/2025.03.19.644182

N/A

0.165DataRank · unranked

2 citations

Neringa Pratuseviciute, Yu‐En Lin, Ayan Adhikari, Wondwossen M Yeshaw, Chloe Flitton +18 more

Multi-omics Characterization of Epigenetic and Genetic Risk of Alzheimer Disease in Autopsied Brains from two Ethnic Groups

medRxiv(2024)10.1101/2024.02.12.24302533

Top 70%

0.165DataRank

Top 70%2 citations

Dolly Reyes‐Dumeyer, Angel Piriz, Patricia Recio, Diones Rivera Mejía, Martin Medrano +20 more

Endolysosomal dysfunction impairs proteostasis and induces neurodegeneration in vivo

iScience(2025)10.1016/j.isci.2025.113460

N/A

0.165DataRank · unranked

2 citations

Ellen A. Albagli, Karen Jansen‐West, Lillian M. Daughrity, Jimei Tong, Anxhela Hysi +17 more

Methylome analysis of FTLD patients with TDP-43 pathology identifies epigenetic signatures specific to pathological subtypes

Molecular Neurodegeneration(2025)10.1186/s13024-025-00869-2

N/A

0.104DataRank · unranked

1 citations

Tejasvi Niranjan, Elise Coopman, Júlia Faura, Sara Alidadiani, Claudia Schrauwen +44 more

Genetic factors and comorbid pathologies interact to drive regional mitophagy alterations in Lewy body dementia

Acta Neuropathologica(2025)10.1007/s00401-025-02964-6

N/A

0.104DataRank · unranked

1 citations

Tyrique Richardson, Michael G. Heckman, Fabienne C. Fiesel, Launia J. White, Shunsuke Koga +4 more

Association between visual hallucinations and α‐synuclein oligomers in patients with dementia with Lewy bodies

Alzheimer s & Dementia(2025)10.1002/alz.70904

N/A

0.104DataRank · unranked

1 citations

Lukas Franke, Daisuke Ono, Michael DeTure, Owen A. Ross, Gregory S. Day +6 more

Erratum to Letters to the Editor regarding: The Second NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol 2021;80(3):210–9

Journal of Neuropathology & Experimental Neurology(2022)10.1093/jnen/nlac003

N/A

0.104DataRank · unranked

1 citations

Jennifer Hammers, Bennet L Omalu, Kevin F. Bieniek, John F. Crary, Dennis W. Dickson +5 more

Evidence of cerebellar TDP-43 loss of function in FTLD-TDP

Acta Neuropathologica Communications(2022)10.1186/s40478-022-01408-6

N/A

0DataRank · unranked

27 citations

Tania F. Gendron, Yuka Koike, Mei Yue, Yuping Song, Jennifer M. Kachergus +14 more

Neuropathologic scales of cerebrovascular disease associated with diffusion changes on MRI

Acta Neuropathologica(2022)10.1007/s00401-022-02465-w

N/A

0DataRank · unranked

26 citations

Naomi Kouri, Sydney A. Labuzan, Scott A. Przybelski, Timothy G. Lesnick, Sheelakumari Raghavan +11 more

The many faces of globular glial tauopathy: A clinical and imaging study

European Journal of Neurology(2022)10.1111/ene.15603

N/A

0DataRank · unranked

25 citations

Shunsuke Koga, Nha Trang Thu Pham, Joseph R. Duffy, David S. Knopman, Farwa Ali +11 more

Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins

Science Translational Medicine(2022)10.1126/scitranslmed.abq3215

N/A

0DataRank · unranked

23 citations

Quinlan T. Mewborne, Amandeep Girdhar, Udit Sheth, Alyssa N. Coyne, Ritika Punathil +23 more

Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy

Journal of Neuropathology & Experimental Neurology(2022)10.1093/jnen/nlac066

N/A

0DataRank · unranked

21 citations

Megan A. Iida, Jonathan D. Cherry, Alicia Casella, Thor D. Stein, Kevin F. Bieniek +56 more

Association of plasma biomarkers of amyloid and neurodegeneration with cerebrovascular disease and Alzheimer's disease

Neurobiology of Aging(2022)10.1016/j.neurobiolaging.2022.07.006

N/A

0DataRank · unranked

17 citations

Michelle M. Mielke, Ekaterina I. Hofrenning, Naomi Kouri, Timothy G. Lesnick, Christina M. Moloney +13 more

Galactosylceramidase deficiency and pathological abnormalities in cerebral white matter of Krabbe disease

Neurobiology of Disease(2022)10.1016/j.nbd.2022.105862

N/A

0DataRank · unranked

17 citations

Shunsuke Koga, Hui Peng, Arulmani Manavalan, Jessica Daiker, Monica Castanedes‐Casey +6 more

APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid

Science Translational Medicine(2020)10.1126/scitranslmed.aay1809

N/A

0DataRank · unranked

163 citations

Olivia N. Attrebi, Yingxue Ren, Wenhui Qiao, Berkiye Sonustun, Yuka A. Martens +19 more

Novel monoclonal antibodies targeting the RRM2 domain of human TDP-43 protein

Neuroscience Letters(2020)10.1016/j.neulet.2020.135353

N/A

0DataRank · unranked

5 citations

Zachary A. Sorrentino, Cara J. Riffe, Grace M. Lloyd, Sydney A. Labuzan, Dennis W. Dickson +4 more

Association of amyloid angiopathy with microbleeds in logopenic progressive aphasia: an imaging‐pathology study

European Journal of Neurology(2020)10.1111/ene.14594

N/A

0DataRank · unranked

7 citations

Joseph R. Duffy, Mary M. Machulda, Anthony J. Spychalla, J Günter, Clifford R. Jack +6 more

Plasma PolyQ-ATXN3 Levels Associate With Cerebellar Degeneration and Behavioral Abnormalities in a New AAV-Based SCA3 Mouse Model

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2022.863089

N/A

0DataRank · unranked

13 citations

Tiffany W. Todd, Lillian M. Daughrity, Mei Yue, Jimei Tong, Yari Carlomagno +11 more

Neuroimmune proteins can differentiate between tauopathies

Journal of Neuroinflammation(2022)10.1186/s12974-022-02640-6

N/A

0DataRank · unranked

13 citations

Zach H. Baucom, Kaleb G. Eppich, Daniel Kirsch, Erin Dixon, Yorghos Tripodis +8 more

Elevated granulocyte colony stimulating factor (CSF) causes cerebellar deficits and anxiety in a model of CSF‐1 receptor related leukodystrophy

Glia(2022)10.1002/glia.24310

N/A

0DataRank · unranked

8 citations

Violeta Chiţu, Jaafar Tindi, Nesha S. Burghardt, Gabriel G. L. Shlager, Harmony C. Ketchum +6 more

Lewy Body Disease is a Contributor to Logopenic Progressive Aphasia Phenotype

Annals of Neurology(2020)10.1002/ana.25979

N/A

0DataRank · unranked

36 citations

Jennifer L. Whitwell, Koji Kasanuki, Jonathan Graff‐Radford, Mary M. Machulda, Joseph R. Duffy +17 more

TDP‐43 pathology effect on volume and flortaucipir uptake in Alzheimer's disease

Alzheimer s & Dementia(2022)10.1002/alz.12878

N/A

0DataRank · unranked

13 citations

Nirubol Tosakulwong, Stephen D. Weigand, Matthew L. Senjem, Christopher G. Schwarz, David S. Knopman +10 more

Asymmetrical Primary Lateral Sclerosis Presenting as Corticobasal Syndrome

Journal of Neuropathology & Experimental Neurology(2022)10.1093/jnen/nlab104

N/A

0DataRank · unranked

6 citations

Shunsuke Koga, Dennis W. Dickson, Aya Murakami

Tau-PET and multimodal imaging in clinically atypical multiple system atrophy masquerading as progressive supranuclear palsy

Parkinsonism & Related Disorders(2022)10.1016/j.parkreldis.2022.06.008

N/A

0DataRank · unranked

6 citations

Hiroaki Sekiya, Shunsuke Koga, Nha Trang Thu Pham, Farwa Ali, Hugo Botha +9 more

HDAC6 Interacts With Poly (GA) and Modulates its Accumulation in c9FTD/ALS

Frontiers in Cell and Developmental Biology(2022)10.3389/fcell.2021.809942

N/A

0DataRank · unranked

6 citations

Yari Carlomagno, Tiffany W. Todd, Caroline Y. Jones, Mercedes Prudencio, Lillian M. Daughrity +16 more

Amyloid fibrils in frontotemporal lobar degeneration with TDP-43 inclusions are composed of TMEM106B, rather than TDP-43

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.01.31.478523

N/A

0DataRank · unranked

1 citations

Qin Cao, M.R. Sawaya, Romany Abskharon, P. Ge, Michael DeTure +6 more

Divergent impacts of C9orf72 repeat expansion on neurons and glia in ALS and FTD

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.11.17.516859

N/A

0DataRank · unranked

1 citations

Manoj K. Jaiswal, Jo-fan Chien, Alexey Kozlenkov, Ping Zhou, Mahammad Gardashli +7 more

Granulocyte Colony Stimulating Factor causes cerebellar deficits and anxiety in a mouse model of CSF-1 receptor-related leukoencephalopathy

bioRxiv (Cold Spring Harbor Laboratory)(2022)10.1101/2022.02.21.481325

N/A

0DataRank · unranked

0 citations

Violeta Chiţu, Jaafar Tindi, Nesha S. Burghardt, Gabriel G. L. Shlager, Harmony C. Ketchum +6 more

Neuroimmune proteins can differentiate between tauopathies

Research Square(2022)10.21203/rs.3.rs-2092813/v1

N/A

0DataRank · unranked

0 citations

Zach H. Baucom, Kaleb G. Eppich, Daniel Kirsch, Erin Dixon, Yorghos Tripodis +8 more

TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A

PLoS Biology(2023)10.1371/journal.pbio.3002028

N/A

0DataRank · unranked

75 citations

Sarah Pickles, Virginia Estades Ayuso, Karen Jansen‐West, Yue Qi, Ziyi Li +9 more

Divergent single cell transcriptome and epigenome alterations in ALS and FTD patients with C9orf72 mutation

Nature Communications(2023)10.1038/s41467-023-41033-y

N/A

0DataRank · unranked

69 citations

Manoj K. Jaiswal, Jo-fan Chien, Alexey Kozlenkov, Jinyoung Jung, Ping Zhou +8 more

TDP-43-regulated cryptic RNAs accumulate in Alzheimer’s disease brains

Molecular Neurodegeneration(2023)10.1186/s13024-023-00646-z

N/A

0DataRank · unranked

62 citations

Sarah Pickles, Tiffany W. Todd, Mei Yue, Karen Jansen‐West, Yuping Song +12 more

Associations of Sex, Race, and Apolipoprotein E Alleles With Multiple Domains of Cognition Among Older Adults

JAMA Neurology(2023)10.1001/jamaneurol.2023.2169

N/A

0DataRank · unranked

57 citations

Alex G. Contreras, Jaclyn M. Eissman, Shubhabrata Mukherjee, Michael L. Lee, Seo‐Eun Choi +88 more

Clinicoradiologic and Neuropathologic Evaluation of Corticobasal Syndrome

Neurology(2023)10.1212/wnl.0000000000207397

N/A

0DataRank · unranked

42 citations

Nha Trang Thu Pham, Hugo Botha, Shunsuke Koga, Naomi Kouri, Farwa Ali +13 more

Plasma biomarkers for prediction of Alzheimer’s disease neuropathologic change

Acta Neuropathologica(2023)10.1007/s00401-023-02594-w

N/A

0DataRank · unranked

40 citations

Jonathan Graff‐Radford, Jeremy A. Syrjanen, Nikki H. Stricker, Alicia Algeciras‐Schimnich, Naomi Kouri +11 more

Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease

Journal of Biological Chemistry(2020)10.1074/jbc.ra120.013638

N/A

0DataRank · unranked

36 citations

Paul M. Seidler, M.R. Sawaya, Duilio Cascio, Tianxiao Yang, Stephan Philipp +11 more

Cerebrovascular pathology and misdiagnosis of multiple system atrophy: An autopsy study

Parkinsonism & Related Disorders(2020)10.1016/j.parkreldis.2020.05.018

N/A

0DataRank · unranked

11 citations

Shanu F. Roemer, Philip W. Tipton, Phillip A. Low, Keith A. Josephs, Dennis W. Dickson +1 more

β-Amyloid Load on PET Along the Continuum of Dementia With Lewy Bodies

Neurology(2023)10.1212/wnl.0000000000207393

N/A

0DataRank · unranked

29 citations

Scott A. Przybelski, Timothy G. Lesnick, Christopher G. Schwarz, Matthew L. Senjem, Jeffrey L. Gunter +23 more

Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases

Journal of Neuropathology & Experimental Neurology(2020)10.1093/jnen/nlaa007

N/A

0DataRank · unranked

12 citations

Zachary A. Sorrentino, Cara J. Riffe, Stefan Prokop, Dennis W. Dickson, Anthony T Yachnis +2 more

Lysosomal polygenic risk is associated with the severity of neuropathology in Lewy body disease

Brain(2023)10.1093/brain/awad183

N/A

0DataRank · unranked

29 citations

Manuela Tan, Shunsuke Koga, Hanneke Geut, Annemieke J.M. Rozemüller, Rebecca R. Valentino +11 more

Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions

Cell Reports(2023)10.1016/j.celrep.2023.112822

N/A

0DataRank · unranked

28 citations

Yanwei Wu, Wei Shao, Tania F. Gendron, Sophie J. F. van der Spek, Grigorii Sultanakhmetov +20 more

Association between transactive response DNA-binding protein of 43 kDa type and cognitive resilience to Alzheimer’s disease: a case-control study

Neurobiology of Aging(2020)10.1016/j.neurobiolaging.2020.04.001

N/A

0DataRank · unranked

22 citations

Jennifer L. Whitwell, Nirubol Tosakulwong, Stephen D. Weigand, Melissa E. Murray, Bradley F. Boeve +6 more

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

Cell Reports(2020)10.1016/j.celrep.2020.107616

N/A

0DataRank · unranked

48 citations

Zachary T. McEachin, Jeannie Chew, Alexander R. Burch, Karen Jansen‐West, Jimei Tong +18 more

Retrospective Evaluation of Neuropathologic Proxies of the Minimal Atrophy Subtype Compared With Corticolimbic Alzheimer Disease Subtypes

Neurology(2023)10.1212/wnl.0000000000207685

N/A

0DataRank · unranked

11 citations

Sydney A. Labuzan, Zhongwei Peng, Billie J. Matchett, Naomi Kouri, Kelly M. Hinkle +10 more

CRISPR interference to evaluate modifiers of C9ORF72-mediated toxicity in FTD

Frontiers in Cell and Developmental Biology(2023)10.3389/fcell.2023.1251551

N/A

0DataRank · unranked

3 citations

Desiree Zanetti Alepuz, Yuka Koike, Mei Yue, Jimei Tong, Pinghu Liu +17 more

Clinicopathological associations of hemispheric dominance in primary progressive apraxia of speech

European Journal of Neurology(2023)10.1111/ene.15764

N/A

0DataRank · unranked

10 citations

Joseph R. Duffy, Heather A. Clark, Rene L. Utianski, Mary M. Machulda, Hugo Botha +8 more

Longitudinal characterization of patients with progressive apraxia of speech without clearly predominant phonetic or prosodic speech features

Brain and Language(2023)10.1016/j.bandl.2023.105314

N/A

0DataRank · unranked

9 citations

Gabriela Meade, Joseph R. Duffy, Heather M. Clark, Hugo Botha, Mary M. Machulda +4 more

Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old

Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad105

N/A

0DataRank · unranked

8 citations

Hiroaki Sekiya, Shunsuke Koga, Rodolfo G. Gatto, Monica Castanedes Casey, Nha Trang Thu Pham +11 more

Comparison of Clinical, Genetic, and Pathologic Features of Limbic and Diffuse Transactive Response DNA-Binding Protein 43 Pathology in Alzheimer’s Disease Neuropathologic Spectrum

Journal of Alzheimer s Disease(2023)10.3233/jad-221094

N/A

0DataRank · unranked

7 citations

Mary M. Machulda, Matthew H. Rutledge, Aivi T. Nguyen, R. Ross Reichard, Matthew Baker +5 more

Investigating the Pathogenic Interplay of Alpha-Synuclein, Tau, and Amyloid Beta in Lewy Body Dementia: Insights from Viral-Mediated Overexpression in Transgenic Mouse Models

Biomedicines(2023)10.3390/biomedicines11102863

N/A

0DataRank · unranked

4 citations

Suelen L. Boschen, Aishe Kurti, Monica Castanedes Casey, Virginia Phillips, John Denis Fryer +6 more

Progressive supranuclear palsy can mimic idiopathic normal pressure hydrocephalus: A case series

Journal of Neuropathology & Experimental Neurology(2023)10.1093/jnen/nlad090

N/A

0DataRank · unranked

3 citations

Shunsuke Koga, Dennis W. Dickson, Miki Kawazoe

Cancer in pathologically confirmed multiple system atrophy

Clinical Autonomic Research(2023)10.1007/s10286-023-00946-w

N/A

0DataRank · unranked

1 citations

Shunsuke Koga, Philip W. Tipton, Hiroaki Sekiya, Owen A. Ross, Ryan J. Uitti +3 more

Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer’s disease: the Alzheimer’s Disease Genetics Consortium

medRxiv(2023)10.1101/2023.07.06.23292311

N/A

0DataRank · unranked

11 citations

Penelope Benchek, Giuseppe Tosto, Nicholas A. Kushch, Jin Sha, Katrina Bazemore +95 more

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.11.09.565552

N/A

0DataRank · unranked

11 citations

Jack Humphrey, Timothy S. Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa +42 more

ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics

bioRxiv (Cold Spring Harbor Laboratory)(2023)10.1101/2023.12.12.571327

N/A

0DataRank · unranked

7 citations

Cory A. Weller, Syed Nisar Hussain Shah, Nicholas L. Johnson, Ying Hao, Jessica Roberts +15 more

Genome-wide association study identifies APOE and ZMIZ1 variants as mitophagy modifiers in Lewy body disease

medRxiv(2023)10.1101/2023.10.16.23297100

N/A

0DataRank · unranked

5 citations

Michael G. Heckman, Fabienne C. Fiesel, Shunsuke Koga, Alexandra I. Soto‐Beasley, Jens O. Watzlawik +14 more

Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: Implications for Alzheimer disease pathogenesis

Research Square(2023)10.21203/rs.3.rs-3464352/v1

N/A

0DataRank · unranked

0 citations

Sagar J. Parikh, Samer O. Abdul‐Hay, Tomoko Sahara, Dongcheul Kang, Dennis W. Dickson +5 more

Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD

Science Translational Medicine(2024)10.1126/scitranslmed.adg7162

N/A

0DataRank · unranked

166 citations

Yue Qi, Anna‐Leigh Brown, Oscar G. Wilkins, Colleen Bereda, Cédric Belair +46 more

Elevated methylation levels, reduced expression levels, and frequent contractions in a clinical cohort of C9orf72 expansion carriers

Molecular Neurodegeneration(2020)10.1186/s13024-020-0359-8

N/A

0DataRank · unranked

53 citations

NiCole A. Finch, Matthew Baker, Jennifer M. Kachergus, Mariely DeJesus‐Hernandez, K.L. Pereira +11 more

Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis

The Lancet Neurology(2024)10.1016/s1474-4422(23)00414-3

N/A

0DataRank · unranked

63 citations

Renaud La Joie, Keir Yong, Federica Agosta, Isabel Elaine Allen, Liana G. Apostolova +82 more

Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease

Acta Neuropathologica(2024)10.1007/s00401-024-02721-1

N/A

0DataRank · unranked

52 citations

Tamil Iniyan Gunasekaran, Michaël E. Belloy, Dolly Reyes‐Dumeyer, Dörthe Jülich, Hüseyin Tayran +25 more

Clinical and pathologic features of cognitive-predominant corticobasal degeneration

Neurology(2020)10.1212/wnl.0000000000009734

N/A

0DataRank · unranked

37 citations

Octavio A. Santos, Otto Pedraza, Irene Litvan, Melissa E. Murray, Ranjan Duara +6 more

Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies

Brain Communications(2020)10.1093/braincomms/fcaa010

N/A

0DataRank · unranked

49 citations

Suman De, Haiyang Jiang, Matteo Rovere, Ming Jin, Ludovica Zaccagnini +12 more

Genetic, transcriptomic, histological, and biochemical analysis of progressive supranuclear palsy implicates glial activation and novel risk genes

Nature Communications(2024)10.1038/s41467-024-52025-x

N/A

0DataRank · unranked

41 citations

Jack Humphrey, Timothy S. Chang, Yi Zhao, Yuk Yee Leung, Pavel P. Kuksa +55 more

Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation

Acta Neuropathologica Communications(2020)10.1186/s40478-020-01079-1

N/A

0DataRank · unranked

55 citations

Yari Carlomagno, Jonathon Sens, Silvia S. Kang, Tanner Jensen, Aishe Kurti +16 more

Sensitive ELISA-based detection method for the mitophagy marker p-S65-Ub in human cells, autopsy brain, and blood samples

Autophagy(2020)10.1080/15548627.2020.1834712

N/A

0DataRank · unranked

66 citations

Xu Hou, Dominika Fričová, Chloe Ramnarine, Sandeep Kumar Barodia, Tania F. Gendron +12 more

HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases

Molecular Neurodegeneration(2024)10.1186/s13024-024-00718-8

N/A

0DataRank · unranked

29 citations

Lillian M. Daughrity, Ellen A. Albagli, Paula Castellanos Otero, Mei Yue, Karen Jansen‐West +20 more

Flortaucipir PET uncovers relationships between tau and amyloid-β in primary age–related tauopathy and Alzheimer’s disease

Science Translational Medicine(2024)10.1126/scitranslmed.ado8076

N/A

0DataRank · unranked

26 citations

Nirubol Tosakulwong, Stephen D. Weigand, Jonathan Graff-Radford, Christopher G. Schwarz, Matthew L. Senjem +11 more

Astrocyte-derived clusterin suppresses amyloid formation in vivo

Molecular Neurodegeneration(2020)10.1186/s13024-020-00416-1

N/A

0DataRank · unranked

68 citations

Jonathon Sens, Silvia S. Kang, Kelsey E. Baker, Taylor J. Berry, Aishe Kurti +8 more

Role of GBA variants in Lewy body disease neuropathology

Acta Neuropathologica(2024)10.1007/s00401-024-02699-w

N/A

0DataRank · unranked

23 citations

Shunsuke Koga, Alexandra Beasley, Launia J. White, Teresa Griesacker, Melissa E. Murray +25 more

Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis

Alzheimer s Research & Therapy(2024)10.1186/s13195-024-01443-6

N/A

0DataRank · unranked

23 citations

Sagar J. Parikh, Samer O. Abdul‐Hay, Tomoko Sahara, Dongcheul Kang, Dennis W. Dickson +5 more

Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration

JAMA Network Open(2024)10.1001/jamanetworkopen.2024.4266

N/A

0DataRank · unranked

21 citations

Annie L Clark, Jack C. Taylor, Hilary W. Heuer, Mark Sanderson‐Cimino, Amy B. Wise +72 more

Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy

Acta Neuropathologica Communications(2020)10.1186/s40478-020-01026-0

N/A

0DataRank · unranked

70 citations

Teresa L. Stackhouse, Leah J. Weston, Patrick C. Kerstein, Valerie R. Osterberg, Clàudia López +6 more

The UFMylation pathway is impaired in Alzheimer’s disease

Molecular Neurodegeneration(2024)10.1186/s13024-024-00784-y

N/A

0DataRank · unranked

17 citations

Michael G. Heckman, Emily C. Craver, Chia‐Chen Liu, Bailey Rawlinson, Xue Wang +8 more

Cathepsin D regulates cerebral Aβ42/40 ratios via differential degradation of Aβ42 and Aβ40

Alzheimer s Research & Therapy(2020)10.1186/s13195-020-00649-8

N/A

0DataRank · unranked

76 citations

Samer O. Abdul‐Hay, Tomoko Sahara, Dongcheul Kang, Monica K. Brizuela, Paul Säftig +4 more

MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study

The Lancet Neurology(2024)10.1016/s1474-4422(24)00083-8

N/A

0DataRank · unranked

23 citations

William J. Scotton, Shanu F. Roemer, Tammaryn Lashley, Michael G. Heckman, Maryam Shoai +95 more

Biomarker‐Based Approach to α‐Synucleinopathies: Lessons from Neuropathology

Movement Disorders(2024)10.1002/mds.30028

N/A

0DataRank · unranked

17 citations

Lea T. Grinberg, Glenda M. Halliday, Irina Alafuzoff, Brittany N. Dugger, Shigeo Murayama +39 more

Clinicoradiological and neuropathological evaluation of primary progressive aphasia

Journal of Neurology Neurosurgery & Psychiatry(2024)10.1136/jnnp-2023-332862

N/A

0DataRank · unranked

15 citations

Nick Corriveau‐Lecavalier, Camilo Bermudez Noguera, Leland R Barnard, Nha Trang Thu Pham, Hugo Botha +20 more

Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia

The American Journal of Human Genetics(2024)10.1016/j.ajhg.2024.05.017

N/A

0DataRank · unranked

14 citations

Demis A. Kia, Raffaele Ferrari, Ganna Leonenko, Beatrice Costa, Valentina Saba +95 more

MAPT haplotype-associated transcriptomic changes in progressive supranuclear palsy

Acta Neuropathologica Communications(2024)10.1186/s40478-024-01839-3

N/A

0DataRank · unranked

14 citations

Jack Humphrey, Ricardo A. Vialle, Bergan Babrowicz, Shrishtee Kandoi, Towfique Raj +5 more

Impact of APOE on amyloid and tau accumulation in argyrophilic grain disease and Alzheimer’s disease

Acta Neuropathologica Communications(2024)10.1186/s40478-024-01731-0

N/A

0DataRank · unranked

13 citations

Sydney V. Doss, Michael G. Heckman, Emily C. Craver, Zonghua Li, Tadafumi C. Ikezu +17 more

Primary Progressive Aphasia Lacking Core Features of Nonfluent and Semantic Variants

Neurology(2024)10.1212/wnl.0000000000209924

N/A

0DataRank · unranked

11 citations

Joseph R. Duffy, Heather M. Clark, Mary M. Machulda, Jonathan Graff‐Radford, Nha Trang Thu Pham +5 more

Alterations of PINK1-PRKN signaling in mice during normal aging

Autophagy Reports(2024)10.1080/27694127.2024.2434379

N/A

0DataRank · unranked

10 citations

Jens O. Watzlawik, Xu Hou, Tyrique Richardson, Nicholas W. Kurchaba, Tingxiang Yan +15 more

Distinct transcriptional alterations distinguish Lewy body disease from Alzheimer’s disease

Brain(2024)10.1093/brain/awae202

N/A

0DataRank · unranked

9 citations

Benjamin E. Rabichow, Aleksandra Wojtas, Michael DeTure, Pamela J. McLean, Dennis W. Dickson +4 more

Abundant transcriptomic alterations in the human cerebellum of patients with a C9orf72 repeat expansion

Acta Neuropathologica(2024)10.1007/s00401-024-02720-2

N/A

0DataRank · unranked

8 citations

Mariely DeJesus‐Hernandez, Shulan Tian, Sofia Pereira das Neves, Richard Crook, NiCole A. Finch +15 more

ProtPipe: A Multifunctional Data Analysis Pipeline for Proteomics and Peptidomics

Genomics Proteomics & Bioinformatics(2024)10.1093/gpbjnl/qzae083

N/A

0DataRank · unranked

8 citations

Cory A. Weller, Syed Islamuddin Shah, Nicholas L. Johnson, Ying Hao, Paige Jarreau +19 more

Relationships between regional burden of tau pathology and age at death and disease duration in PSP

Parkinsonism & Related Disorders(2024)10.1016/j.parkreldis.2024.107109

N/A

0DataRank · unranked

7 citations

Nirubol Tosakulwong, Stephen D. Weigand, Farwa Ali, Heather M. Clark, Julie A. G. Stierwalt +6 more

Generation and characterization of monoclonal antibodies against pathologically phosphorylated TDP-43

PLoS ONE(2024)10.1371/journal.pone.0298080

N/A

0DataRank · unranked

6 citations

Tiffany W. Todd, Wei Shao, Caroline J. Jones, Kexin Huang, Lillian M. Daughrity +9 more

Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W

Cells(2024)10.3390/cells13181540

N/A

0DataRank · unranked

6 citations

Liam T. Cocker, Matt Coban, Caleb A. Weber, Jenny M. Bredenberg, Paige K Boneski +12 more

Loss of TMEM106B leads to myelination deficits: implications for frontotemporal dementia treatment strategies

Brain(2020)10.1093/brain/awaa141

N/A

0DataRank · unranked

79 citations

Alexandra M. Nicholson, Yingxue Ren, Mieu Brooks, Peizhou Jiang, Aamir Zuberi +17 more

Primary Progressive Apraxia of Speech Caused by TDP-43

Neurology Genetics(2024)10.1212/nxg.0000000000200134

N/A

0DataRank · unranked

2 citations

Jennifer L. Whitwell, Dennis W. Dickson, Joseph R. Duffy, Heather M. Clark, J. Eric Ahlskog +4 more

Utilizing quantitative susceptibility mapping to differentiate primary lateral sclerosis from progressive supranuclear palsy: A case report

Neuropathology(2024)10.1111/neup.13015

N/A

0DataRank · unranked

1 citations

Ryota Satoh, Farwa Ali, Dennis W. Dickson, Jennifer L. Whitwell, Keith A. Josephs +1 more

TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.01.22.575730

N/A

0DataRank · unranked

25 citations

Anastasiia Lovchykova, Tetsuya Akiyama, Chang Liu, Caiwei Guo, Vidhya Maheswari Jawahar +7 more

Association of Structural Forms of 17q21.31 with the Risk of Progressive Supranuclear Palsy and MAPT Sub-haplotypes

medRxiv(2024)10.1101/2024.02.26.24303379

N/A

0DataRank · unranked

0 citations

Timothy S. Chang, Beth A. Dombroski, Po‐Liang Cheng, Yaqin Si, Albert Tucci +59 more

Determinants of confrontation naming deficits on the Boston Naming Test associated with transactive response DNA-binding protein 43 pathology

Journal of the International Neuropsychological Society(2024)10.1017/s1355617724000146

N/A

0DataRank · unranked

0 citations

Austin W. Goodrich, Stephen D. Weigand, Nha Trang Thu Pham, Arenn F. Carlos, Marina Buciuc +11 more

Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies

bioRxiv (Cold Spring Harbor Laboratory)(2024)10.1101/2024.03.25.585597

N/A

0DataRank · unranked

0 citations

Melissa C. Wren, Feilin Liu, Naomi Kouri, Anastasiia Maistrenko, Bilal Khalil +7 more

Chromogranin A Deficiency Attenuates Tauopathy by Altering Epinephrine–Alpha-Adrenergic Receptor Signaling

Research Square(2024)10.21203/rs.3.rs-4797912/v1

N/A

0DataRank · unranked

0 citations

Suborno Jati, Daniel Muñoz-Mayorga, Shandy Shahabi, Kechun Tang, Yuren Tao +5 more

Prominent loss of striatal dopamine transporter binding in frontotemporal lobar degeneration with the MAPT N279K mutation present as early as at prodromal stage without parkinsonism

Parkinsonism & Related Disorders(2024)10.1016/j.parkreldis.2024.107144

N/A

0DataRank · unranked

0 citations

Cynthia Vernon, Scott A. Przybelski, Hoon‐Ki Min, Julie A. Fields, Bradford C. Dickerson +6 more

APOE genotype determines cell-type-specific pathological landscape of Alzheimer’s disease

Neuron(2025)10.1016/j.neuron.2025.02.017

N/A

0DataRank · unranked

29 citations

Yuka A. Martens, Yingxue Ren, Yunjung Jin, Hiroaki Sekiya, Sydney V. Doss +25 more

TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

Nature Neuroscience(2025)10.1038/s41593-025-02049-3

N/A

0DataRank · unranked

29 citations

Anastasiia Lovchykova, Tetsuya Akiyama, Stephanie L. Rayner, Vidhya Bharathi, Chang Liu +8 more

TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in amyotrophic lateral sclerosis and frontotemporal dementia

Journal of Clinical Investigation(2025)10.1172/jci182088

N/A

0DataRank · unranked

24 citations

Ya Cui, Sebastian Michels, Michael R. Colwin, Cameron Stockford, Wenbin Ye +19 more

Comprehensive cross-sectional and longitudinal comparisons of plasma glial fibrillary acidic protein and neurofilament light across FTD spectrum disorders

Molecular Neurodegeneration(2025)10.1186/s13024-025-00821-4

N/A

0DataRank · unranked

19 citations

Linn Öijerstedt, Michael G. Heckman, Launia J. White, Hilary W. Heuer, Argentina Lario Lago +37 more

Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations

Acta Neuropathologica Communications(2020)10.1186/s40478-020-01037-x

N/A

0DataRank · unranked

105 citations

Erica Modeste, Eric B. Dammer, Paola Merino, Georgia Taylor, Duc M. Duong +7 more

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study

The Lancet Neurology(2020)10.1016/s1474-4422(20)30394-x

N/A

0DataRank · unranked

120 citations

Shunsuke Koga, Rebecca R. Valentino, Regina Hertfelder Reynolds, Raffaele Ferrari, Manuela Tan +51 more

Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

Journal of Clinical Investigation(2020)10.1172/jci139741

N/A

0DataRank · unranked

258 citations

Jack Humphrey, Sarah Pickles, Anna‐Leigh Brown, Sarah E. Hill, Jennifer M. Kachergus +47 more

Chromogranin A deficiency attenuates tauopathy by altering epinephrine–alpha-adrenergic receptor signaling in PS19 mice

Nature Communications(2025)10.1038/s41467-025-59682-6

N/A

0DataRank · unranked

13 citations

Daniel Muñoz-Mayorga, Shandy Shahabi, Kechun Tang, Yuren Tao, Dennis W. Dickson +5 more

Relation of Alzheimer's disease-related TDP-43 proteinopathy to metrics from diffusion tensor imaging (DTI) and neurite orientation dispersion and density imaging (NODDI)

Neurobiology of Aging(2025)10.1016/j.neurobiolaging.2025.03.001

N/A

0DataRank · unranked

11 citations

Nha Trang Thu Pham, Robert I. Reid, Bradley F. Boeve, David S. Knopman, Ronald C. Petersen +7 more

Rod-shaped microglia interact with neuronal dendrites to attenuate cortical excitability during TDP-43-related neurodegeneration

Immunity(2025)10.1016/j.immuni.2025.08.016

N/A

0DataRank · unranked

11 citations

Yue Liang, Alessandra S. Miller, Praveen N. Pallegar, Anthony D. Umpierre, Na Wang +14 more

Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS

Cell(2025)10.1016/j.cell.2025.07.045

N/A

0DataRank · unranked

9 citations

Mingee Chung, Sabrina A. Stratton, Chang Hee Han, Woo Jae Kim, Udit Sheth +28 more

Impact of APOE on cerebrovascular lipid profile in Alzheimer’s disease

Acta Neuropathologica(2025)10.1007/s00401-025-02949-5

N/A

0DataRank · unranked

6 citations

Hu Wang, Michael G. Heckman, Yingxue Ren, Launia J. White, Wenyan Lü +12 more

TDP‐43 Cryptic RNAs in Perry Syndrome: Differences across Brain Regions and TDP‐43 Proteinopathies

Movement Disorders(2025)10.1002/mds.30104

N/A

0DataRank · unranked

11 citations

Jesús González Bejarano, Anand Narayan, Lillian M. Daughrity, Candela Maroto Cidfuentes, Madison M. Reeves +18 more

Development and validation of a sensitive sandwich ELISA against human PINK1

Autophagy(2025)10.1080/15548627.2025.2457915

N/A

0DataRank · unranked

8 citations

Jens O. Watzlawik, Bernardo A. Bustillos, Gabriella Fiorino, Tingxiang Yan, Szymon L. Lewicki +7 more

Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains

Cell(2020)10.1016/j.cell.2020.01.027

N/A

0DataRank · unranked

425 citations

Christina E. Lee, Yari Carlomagno, Mukesh Kumar, Duc M. Duong, Hendrik Wesseling +11 more

Substantia Nigra Iron Deposition in Lewy Body Disease: A Magnetic Resonance Imaging and Neuropathology Study

Movement Disorders(2025)10.1002/mds.30265

N/A

0DataRank · unranked

8 citations

Scott A. Przybelski, Timothy G. Lesnick, Melissa E. Murray, Aivi T. Nguyen, Ross R. Reichard +24 more

Sex differences for regional pathology in people with a high likelihood of Lewy body dementia phenotype based on underlying pathology

Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring(2025)10.1002/dad2.70083

N/A

0DataRank · unranked

6 citations

David G. Coughlin, Shunsuke Koga, Owen A. Ross, Irene Litvan, Dennis W. Dickson +1 more

Analysis of the splicing landscape of the frontal cortex in FTLD-TDP reveals subtype specific patterns and cryptic splicing

Acta Neuropathologica(2025)10.1007/s00401-025-02901-7

N/A

0DataRank · unranked

6 citations

Bavo Heeman, Cyril Pottier, Matthew Baker, Mariely DeJesus‐Hernandez, Fahri Küçükali +23 more

Impact of hippocampal α‐synuclein oligomers on cognitive trajectory in patients with dementia with Lewy bodies

Alzheimer s & Dementia(2025)10.1002/alz.70374

N/A

0DataRank · unranked

6 citations

Lukas Franke, Daisuke Ono, Michael DeTure, Owen A. Ross, Melissa E. Murray +4 more

LATE-NC Stage 3: a diagnostic rubric to differentiate severe LATE-NC from FTLD-TDP

Acta Neuropathologica(2025)10.1007/s00401-025-02876-5

N/A

0DataRank · unranked

5 citations

Yuriko Katsumata, Dennis W. Dickson, Nikhil B Ghayal, Khine Zin Aung, Xian Wu +13 more

Brain transcriptomics highlight abundant gene expression and splicing alterations in non-neuronal cells in aFTLD-U

Acta Neuropathologica(2025)10.1007/s00401-025-02919-x

N/A

0DataRank · unranked

4 citations

Júlia Faura, Sarah Wynants, Nemo Peeters, Marleen Van den Broeck, Linus De Witte +40 more

White matter hyperintensities and TDP‐43 pathology in Alzheimer's disease

Alzheimer s & Dementia(2025)10.1002/alz.14516

N/A

0DataRank · unranked

4 citations

Stephen D. Weigand, Nha Trang Thu Pham, Ronald C. Petersen, Clifford R. Jack, Dennis W. Dickson +3 more

Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers

Alzheimer s & Dementia(2025)10.1002/alz.70734

N/A

0DataRank · unranked

4 citations

Lea T. Grinberg, Jared T. Ahrendsen, Thomas G. Beach, Kevin F. Bieniek, Rudolph J. Castellani +41 more

Uncovering Image‐Driven Subtypes with Distinct Pathology and Clinical Course in Autopsy‐Confirmed Four Repeat Tauopathies

Annals of Neurology(2025)10.1002/ana.27286

N/A

0DataRank · unranked

3 citations

Hiroaki Sekiya, Farwa Ali, Heather M. Clark, Rene L. Utianski, Joseph R. Duffy +5 more

White matter hyperintensities in the deep cerebral venous territory differ between subcortical and cortical 4-repeat tauopathies

Parkinsonism & Related Disorders(2025)10.1016/j.parkreldis.2025.108170

N/A

0DataRank · unranked

1 citations

Ryota Satoh, Farwa Ali, Heather M. Clark, Julie A. G. Stierwalt, Yehkyoung C. Stephens +6 more

Neuronal ABCA7 deficiency aggravates mitochondrial dysfunction and neurodegeneration in Alzheimer's disease

Alzheimer s & Dementia(2025)10.1002/alz.70112

N/A

0DataRank · unranked

5 citations

Yining Pan, Skylar C Starling, Devon H. Haskell, Astrid Quintero, Keiji Kawatani +18 more

Machine Learning Models of Voxel‐Level [18F] Fluorodeoxyglucose Positron Emission Tomography Data Excel at Predicting Progressive Supranuclear Palsy Pathology

Annals of Neurology(2025)10.1002/ana.27265

N/A

0DataRank · unranked

2 citations

Ryota Satoh, Nha Trang Thu Pham, Neha Atulkumar Singh, Farwa Ali, Dennis W. Dickson +4 more

Pick's disease presenting as progressive apraxia of speech: Atypical clinical and neuroimaging features in three autopsy-confirmed cases

Clinical Neurology and Neurosurgery(2025)10.1016/j.clineuro.2025.109018

N/A

0DataRank · unranked

1 citations

Jonathan Graff-Radford, Rene L. Utianski, Joseph R. Duffy, Heather M. Clark, Mary M. Machulda +5 more

The Neurofibrillary Tangle Maturity Scale: A Novel Framework for Tangle Pathology Evaluation in Alzheimer’s Disease

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.06.02.657435

N/A

0DataRank · unranked

2 citations

Matthew H. Rutledge, Sydney A. Labuzan, Zhongwei Peng, Jessica F. Tranovich, Ashley Wood +9 more

Integrative multiomic analysis links TDP-43-driven splicing defects to cascading proteomic disruption of ALS/FTD pathways

bioRxiv (Cold Spring Harbor Laboratory)(2025)10.1101/2025.09.29.679403

N/A

0DataRank · unranked

2 citations

Zhengde Liu, Keyana Blake, Yue Qi, Sasha Rollinson, Sahba Seddighi +13 more

Classification of Tauopathies from Human Brain Homogenates through Salt-Modulated Tau Amplification

medRxiv(2025)10.1101/2025.08.05.25331458

N/A

0DataRank · unranked

1 citations

Michael A. Metrick, Pu Xu, Shunsuke Koga, Bernardino Ghetti, Dennis W. Dickson +3 more

Frontotemporal Lobar degeneration with TDP-43 presenting as progressive supranuclear palsy syndrome

Acta Neuropathologica Communications(2025)10.1186/s40478-025-02058-0

N/A

0DataRank · unranked

0 citations

Shunsuke Koga, Hiroaki Sekiya, Masataka Nakamura, Yusuke Yakushiji, Dennis W. Dickson +1 more

Diagnostic utility of tectal plate measures in clinical variants of progressive supranuclear palsy

Journal of Neurology(2025)10.1007/s00415-025-13256-0

N/A

0DataRank · unranked

0 citations

Morgan Blakey, Ryota Satoh, Farwa Ali, Nha Trang Thu Pham, Abigail Amrami +5 more

Relationships between neuronal loss, age of death, disease duration and MRI brain volumes in progressive supranuclear palsy

Parkinsonism & Related Disorders(2025)10.1016/j.parkreldis.2025.107980

N/A

0DataRank · unranked

0 citations

Shanu F. Roemer, Nirubol Tosakulwong, Stephen D. Weigand, Farwa Ali, Heather M. Clark +6 more

Describing the diversity of MAPT transcripts in the parietal cortex of Pick’s disease patients

npj Dementia(2025)10.1038/s44400-025-00027-x

N/A

0DataRank · unranked

0 citations

Maximilian G. Stuber, Marios Gavrielatos, Alexandra I. Soto‐Beasley, Michael G. Heckman, Melissa E. Murray +7 more

Quantitative Susceptibility Mapping and Iron Deposition in Autopsy‐Confirmed Progressive Supranuclear Palsy

Movement Disorders Clinical Practice(2025)10.1002/mdc3.70357

N/A

0DataRank · unranked

0 citations

Hiroaki Sekiya, Farwa Ali, Dennis W. Dickson, Jennifer L. Whitwell, Keith A. Josephs +1 more

Clinicopathological and Neuroimaging Correlates of Disease Duration in Primary Progressive Apraxia of Speech

European Journal of Neurology(2025)10.1111/ene.70366

N/A

0DataRank · unranked

0 citations

Heather M. Clark, Joseph R. Duffy, Mary M. Machulda, Anna Lavrova, Jerusha Bhaskaran +5 more

Sphingolipid and ceramide associations with tau pathology vary across diverse ethnoracial groups in postmortem brain tissue

medRxiv(2025)10.1101/2025.11.04.25339489

N/A

0DataRank · unranked

0 citations

Richa Batra, Kevin Huynh, Collette Blach, Alexandra Kueider‐Paisley, Joseph S. Reddy +16 more

Clinical and Pathological Features of CSF1R-Related Disorder Associated With the p.R777Q Pathogenic Variant

Journal of Movement Disorders(2025)10.14802/jmd.25247

N/A

0DataRank · unranked

0 citations

Delaney Liskey, Audrey Strongosky, Stuart J. McCarter, Paula Sandroni, Dennis W. Dickson +2 more

123 I-FP-CIT SPECT in Autopsy-Proven Lewy Body Disease

Neurology Open Access(2025)10.1212/wn9.0000000000000048

N/A

0DataRank · unranked

0 citations

Scott A. Przybelski, Cynthia J. Vernon, Hoon‐Ki Min, Leah K. Forsberg, Julie A. Fields +21 more

The AD tau core spontaneously self-assembles and recruits full-length tau to filaments

Cell Reports(2021)10.1016/j.celrep.2021.108843

N/A

0DataRank · unranked

59 citations

Sireesha Manne, Michael DeTure, Mercedes Prudencio, Yong‐Jie Zhang, Rana Hanna Al‐Shaikh +12 more

Deep Learning-Based Image Classification in Differentiating Tufted Astrocytes, Astrocytic Plaques, and Neuritic Plaques

Journal of Neuropathology & Experimental Neurology(2021)10.1093/jnen/nlab005

N/A

0DataRank · unranked

56 citations

Nikhil B Ghayal, Dennis W. Dickson, Shunsuke Koga

Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids

Acta Neuropathologica(2021)10.1007/s00401-021-02361-9

N/A

0DataRank · unranked

58 citations

Wenyan Lü, Yingxue Ren, Yuan Fu, Yuka A. Martens, Francis Shue +18 more

Deep learning‐based model for diagnosing Alzheimer's disease and tauopathies

Neuropathology and Applied Neurobiology(2021)10.1111/nan.12759

N/A

0DataRank · unranked

83 citations

Akihiro Ikeda, Dennis W. Dickson, Shunsuke Koga

Tau isoforms are differentially expressed across the hippocampus in chronic traumatic encephalopathy and Alzheimer’s disease

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01189-4

N/A

0DataRank · unranked

84 citations

Camille D. Esnault, Zachary Baucom, Yorghos Tripodis, Bertrand R. Huber, Victor E. Alvarez +4 more

Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study

Acta Neuropathologica Communications(2021)10.1186/s40478-021-01233-3

N/A

0DataRank · unranked

90 citations

Kurt Farrell, Jamie M. Walker, Timothy E. Richardson, Gabriel A. Marx, Clare Bryce +20 more

Latent trait modeling of tau neuropathology in progressive supranuclear palsy

Acta Neuropathologica(2021)10.1007/s00401-021-02289-0

N/A

0DataRank · unranked

21 citations

Melissa E. Murray, Joseph S. Reddy, Daniel Serie, Alexandra I. Soto‐Beasley, Mariet Allen +14 more

Relationship Between18F-Flortaucipir Uptake and Histologic Lesion Types in 4-Repeat Tauopathies

Journal of Nuclear Medicine(2021)10.2967/jnumed.121.262685

N/A

0DataRank · unranked

21 citations

Nirubol Tosakulwong, Stephen D. Weigand, Marina Buciuc, Val J. Lowe, Dennis W. Dickson +2 more

Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS

Science Translational Medicine(2021)10.1126/scitranslmed.abe1923

N/A

0DataRank · unranked

148 citations

Victoria Baskerville, Benjamin L. Zaepfel, Dennis W. Dickson, Frank Rigo, Frank Bennett +3 more

Enrichment of Phosphorylated Tau (Thr181) and Functionally Interacting Molecules in Chronic Traumatic Encephalopathy Brain-derived Extracellular Vesicles

Aging and Disease(2021)10.14336/ad.2020.1007

N/A

0DataRank · unranked

13 citations

Weiwei Lin, Kayo Takamatsu-Yukawa, Jianqiao Hu, Seiko Ikezu, Michael DeTure +4 more

Cellular and pathological heterogeneity of primary tauopathies

Molecular Neurodegeneration(2021)10.1186/s13024-021-00476-x

N/A

0DataRank · unranked

233 citations

Shanu F. Roemer, Leonard Petrucelli, Dennis W. Dickson, Dah‐eun Chloe Chung

Nanoparticles With Affinity for α-Synuclein Sequester α-Synuclein to Form Toxic Aggregates in Neurons With Endolysosomal Impairment

Frontiers in Molecular Neuroscience(2021)10.3389/fnmol.2021.738535

N/A

0DataRank · unranked

10 citations

Ming Gan, Shu‐Hui Yen, Dennis W. Dickson, Peizhou Jiang

Authors’ Response

Journal of Neuropathology & Experimental Neurology(2021)10.1093/jnen/nlab066.001

N/A

0DataRank · unranked

8 citations

John F. Crary, Dennis W. Dickson, Thor D. Stein, Jesse Mez, Michael E Alosco +2 more

Capgras syndrome in dementia with Lewy bodies: a possible association of severe cortical Lewy body pathology

Neurologia i Neurochirurgia Polska(2021)10.5603/pjnns.a2021.0086

N/A

0DataRank · unranked

7 citations

Dennis W. Dickson, Zbigniew K. Wszołek, Shunsuke Koga

Modulating innate immune activation states impacts the efficacy of specific Aβ immunotherapy

Molecular Neurodegeneration(2021)10.1186/s13024-021-00453-4

N/A

0DataRank · unranked

6 citations

Cory C. Funk, Xue Wang, Paramita Chakrabarty, Karen N. McFarland, Baxter Bramblett +14 more

The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins

UNC Libraries(2020)10.17615/6qag-q019

N/A

0DataRank · unranked

0 citations

Adeela Kamal, Dennis W. Dickson, Francis Burrows, N. Stanley Nahman, Natalia Klosak +11 more

TDP-43 represses cryptic exon inclusion in FTD/ALS gene UNC13A

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.04.02.438213

N/A

0DataRank · unranked

20 citations

Mercedes Prudencio, Yuka Koike, Sarat C. Vatsavayai, Garam Kım, Fred Harbinski +22 more

Re: The Second NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol 2021;80(3):210–9

Journal of Neuropathology & Experimental Neurology(2021)10.1093/jnen/nlab066

N/A

0DataRank · unranked

14 citations

Jennifer Hammers, Bennet L Omalu, Kevin F. Bieniek, John F. Crary, Dennis W. Dickson +5 more

Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study

bioRxiv (Cold Spring Harbor Laboratory)(2021)10.1101/2021.06.08.447553

N/A

0DataRank · unranked

7 citations

Kurt Farrell, Jamie M. Walker, Timothy E. Richardson, Gabe Marx, Clare Bryce +20 more

Deletion of the Ubiquitin Ligase CHIP Leads to the Accumulation, But Not the Aggregation, of Both Endogenous Phospho- and Caspase-3-Cleaved Tau Species

UNC Libraries(2021)10.17615/vm3k-rq43

N/A

0DataRank · unranked

0 citations

Mei Yue, Christopher B. Eckman, Judith Dunmore, Chris W. Lee, Dennis W. Dickson +11 more

Associations of Mitochondrial Genomic Variation with Corticobasal Degeneration, Progressive Supranuclear Palsy, and Neuropathological Tau Measures

bioRxiv (Cold Spring Harbor Laboratory)(2020)10.1101/2020.07.10.196097

N/A

0DataRank · unranked

0 citations

Nikoleta Tamvaka, Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto‐Beasley, Ronald L. Walton +6 more

Structure-based discovery of small molecules that disaggregate Alzheimer’s disease tissue derived tau fibrils in vitro

Nature Communications(2022)10.1038/s41467-022-32951-4

N/A

0DataRank · unranked

187 citations

Kevin A. Murray, David R. Boyer, P. Ge, M.R. Sawaya, Carolyn J. Hu +9 more

Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43

Nature(2022)10.1038/s41586-022-04670-9

N/A

0DataRank · unranked

180 citations

Qin Cao, M.R. Sawaya, Romany Abskharon, P. Ge, Michael DeTure +6 more

LATE-NC staging in routine neuropathologic diagnosis: an update

Acta Neuropathologica(2022)10.1007/s00401-022-02524-2

N/A

0DataRank · unranked

178 citations

Edward B. Lee, Matthew D. Cykowski, Irina Alafuzoff, Konstantinos Arfanakis, Johannes Attems +45 more

APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer’s disease with Lewy body pathology

Acta Neuropathologica(2022)10.1007/s00401-022-02421-8

N/A

0DataRank · unranked

72 citations

Fuyao Li, Berkiye Sonoustoun, Naveen Kondru, Yuka A. Martens, Wenhui Qiao +14 more

Apoptotic Neuron-Derived Histone Amyloid Fibrils Induce α-Synuclein Aggregation

Molecular Neurobiology(2020)10.1007/s12035-020-02167-y

N/A

0DataRank · unranked

3 citations

Ming Gan, Dennis W. Dickson, Peizhou Jiang

ASLPrep: a platform for processing of arterial spin labeled MRI and quantification of regional brain perfusion

Nature Methods(2022)10.1038/s41592-022-01458-7

N/A

0DataRank · unranked

49 citations

Maxwell A. Bertolero, Sudipto Dolui, Matthew Cieslak, Kristin Murtha, Erica B. Baller +94 more

Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy

Molecular Neurodegeneration(2022)10.1186/s13024-022-00585-1

N/A

0DataRank · unranked

48 citations

Deepak Chhangani, Melissa C. Wren, Courtney L. Smith, Jannifer H. Lee, Xingli Li +23 more

Longitudinal atrophy in prodromal dementia with Lewy bodies points to cholinergic degeneration

Brain Communications(2022)10.1093/braincomms/fcac013

N/A

0DataRank · unranked

37 citations

Zuzana Nedelská, Qin Chen, Matthew L. Senjem, Christopher G. Schwarz, Jeffrey L. Gunter +19 more

GRN Mutations Are Associated with Lewy Body Dementia

Movement Disorders(2022)10.1002/mds.29144

N/A

0DataRank · unranked

24 citations

Shunsuke Koga, Zalak Shah, Ruth Chia, Rosa Rademakers, Clifton L. Dalgard +6 more

LRP10 variants in progressive supranuclear palsy

Neurobiology of Aging(2020)10.1016/j.neurobiolaging.2020.04.016

N/A

0DataRank · unranked

9 citations

Shamiram Melhem, Laura Donker Kaat, Wang Zheng Chiu, Demy J.S. Kuipers, Guido J. Breedveld +13 more

Prion-like α-synuclein pathology in the brain of infants with Krabbe disease

Brain(2022)10.1093/brain/awac002

N/A

0DataRank · unranked

28 citations

Simona S. Ghanem, David J. Koss, Ilham Y. Abdi, Elizabeth Gibbons, Rita Guerreiro +71 more

Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

Scientific Reports(2022)10.1038/s41598-022-09825-2

N/A

0DataRank · unranked

28 citations

John C. Earls, Andrew T. Magis, Sergey A. Kornilov, Jennifer C. Lovejoy, Cory C. Funk +94 more

Diffusion tractography of superior cerebellar peduncle and dentatorubrothalamic tracts in two autopsy confirmed progressive supranuclear palsy variants: Richardson syndrome and the speech-language variant

NeuroImage Clinical(2022)10.1016/j.nicl.2022.103030

N/A

0DataRank · unranked

27 citations

Peter R. Martin, Farwa Ali, Heather M. Clark, Joseph R. Duffy, Rene L. Utianski +6 more